support the site ⋅ become a member ⋅ unscramble the egg
(tag_directory)
free120  nbme24  nbme23  nbme22  nbme21  nbme20  nbme19  nbme18  nbme17  nbme16  nbme15  nbme13 

NBME 24

Block/Question (62.4 difficulty score)
A researcher hypothesizes that exposure to more than 50 μg/L ...
Case-control study

Block/Question (18.3 difficulty score)
A 43-year-old woman with a 2-year history of labile ...
Unopposed α-adrenergic tone

Block/Question (35.6 difficulty score)
A 52-year-old woman comes to the physician because of severe ...
Intercostal

Block/Question (28.4 difficulty score)
A 28-year-old man with AIDS has fever, headache, and ...
Lungs

Block/Question (36.4 difficulty score)
The 35-year-old woman indicated by the arrow has a family ...
X-linked recessive

Block/Question (34.9 difficulty score)
A 57-year-old woman requires intubation in the intensive care ...
Acute lung injury

Block/Question (26.7 difficulty score)
A 65-year-old woman comes to the physician because of blood ...
Cigarette smoking

Block/Question (43.1 difficulty score)
A 24-year-old woman at 28 weeks' gestation is brought to the ...
Tremor

Block/Question (16.2 difficulty score)
The graph shows expiratory pressure-volume curves that ...
Diffuse pulmonary fibrosis

Block/Question (35.6 difficulty score)
A 75-year-old man is brought unconscious to the emergency ...
Atherosclerosis

Block/Question (42.9 difficulty score)
A 55-year-old man with type 1 diabetes mellitus comes to the ...
Persistent activation of voltage-gated Na+ channels in the nociceptor

Block/Question (11.9 difficulty score)
A 26-year-old man comes to the physician for a follow-up ...
Increased number of LDL receptors on hepatocytes

Block/Question (48.4 difficulty score)
A 4-year-old boy is brought to the emergency department by ...
Proliferative glomerulonephritis

Block/Question (18.3 difficulty score)
A thin 66-year-old man is brought to the emergency department ...
Urine osmolality > plasma osmolality

Block/Question (39.5 difficulty score)
Results of a 5-year screening program for HIV infection in a ...
5%

Block/Question (28.1 difficulty score)
A 32-year-old man is brought to the emergency department ...
Flexion at the distal interphalangeal joint

Block/Question (19.2 difficulty score)
A 3-year-old boy is brought to the emergency department ...
Annular pancreas

Block/Question (22.7 difficulty score)
A 34-year-old woman with a long history of rheumatoid ...
Tuberculous osteomyelitis

Block/Question (10.4 difficulty score)
A 35-year-old man comes to the physician because of a 1-week ...
Cluster headache

Block/Question (42.9 difficulty score)
Immediately after a spontaneous vaginal delivery, a full-term ...
Fusion of the sclerotomes

Block/Question (25.5 difficulty score)
A 35-year-old woman comes to the physician because of a ...
Foramen cecum

Block/Question (24.9 difficulty score)
A 50-year-old man undergoes surgical transection of the ...
Adductor brevis

Block/Question (22.9 difficulty score)
A 50-year-old man comes to the physician because of diarrhea ...
Generalized malabsorption

Block/Question (19.9 difficulty score)
A 6-year-old girl is brought to the office by her mother ...
Pediculus humanus capitis

Block/Question (26.3 difficulty score)
A 7-year-old boy has metabolic acidosis and persistent ...
Area labeled ‘B’ (Proximal convoluted tubule)

Block/Question (19.3 difficulty score)
An 80-year-old woman with poorly controlled type 2 diabetes ...
Hematocrit: decreased;
Serum parathyroid hormone: increased;
Serum calcitriol: decreased


Block/Question (34.5 difficulty score)
A 10-year-old girl with a lifelong history of intermittent ...
Palpable right ventricular lift

Block/Question (41.8 difficulty score)
A 32-year-old woman comes to the physician because of a 7-day ...
Eosinophils

Block/Question (15.6 difficulty score)
An 80-year-old woman comes to the physician because of a ...
Determination of erythrocyte sedimentation rate

Block/Question (36.9 difficulty score)
A 55-year-old man is brought to the emergency department ...
Pulmonary capillary wedge pressure: increased;
Cardiac output: decreased;
Systemic vascular resistance: increased


Block/Question (42.6 difficulty score)
An experimental study is conducted to examine the function of ...
Post-translational modification

Block/Question (42.5 difficulty score)
A 24-year-old man receives an injection of histamine in the ...
Increased lymph flow

Block/Question (13.5 difficulty score)
A 3-month-old girl is brought to the emergency department by ...
Human papillomavirus

Block/Question (16.8 difficulty score)
A 62-year-old man comes to the physician for a follow-up ...
Sotalol

Block/Question (31.8 difficulty score)
A 1616-g (3-lb 9-oz) male newborn is delivered to a ...
Bronchopulmonary dysplasia

Block/Question (14.2 difficulty score)
A 4-year-old girl is brought to the physician because of a ...
Villous atrophy

Block/Question (24.4 difficulty score)
A 25-year-old woman at 16 weeks' gestation comes to the ...
Increased hepatic production of T4-binding globulin

Block/Question (14.3 difficulty score)
A 37-year-old woman comes to the physician because of nausea ...
Borderline

Block/Question (19.7 difficulty score)
A 40-year-old man with AIDS develops severe diarrhea that is ...
Somatostatin

Block/Question (36.4 difficulty score)
A 26-year-old man and his 25-year-old wife come to the ...
One in four will have 25% β-globin function and may require occasional transfusions

Block/Question (12.2 difficulty score)
A 32-year-old woman who is 20 weeks' pregnant has had ...
Misoprostol

Block/Question (23.3 difficulty score)
A 68-year-old woman with acute myelogenous leukemia begins ...
Granulocyte-macrophage colony-stimulating factor

Block/Question (14.0 difficulty score)
After completing 6 courses of chemotherapy for cancer of the ...
Doxorubicin

Block/Question (14.2 difficulty score)
A 24-year-old man is brought to the office because of fever ...
Alteration in DNA gyrase

Block/Question (30.9 difficulty score)
A 71-year-old man is brought to the emergency department ...
Area labeled ‘D’ (Posterior inferior cerebellar artery)

Block/Question (15.9 difficulty score)
A 10-year-old girl is scheduled to undergo fixation of a ...
Succinylcholine

Block/Question (19.8 difficulty score)
A 35-year-old man comes to the physician 1 week after he had ...
Increased serum angiotensin II concentration

Block/Question (22.2 difficulty score)
A 70-year-old man is brought to the emergency department ...
Stroke volume: decreased;
Left ventricular end-diastolic volume: increased;
Cardiac output: decreased


Block/Question (20.7 difficulty score)
A 58-year-old man is brought to the emergency department 1 ...
Ruptured spleen

Block/Question (47.8 difficulty score)
An 11-year-old boy is brought to the emergency department by ...
Intracellular and extracellular dehydration

Block/Question (41.8 difficulty score)
A 73-year-old woman has had easy fatigability for 2 years. ...
Failure of conversion of N5-methyltetrahydrofolate to tetrahydrofolate

Block/Question (28.5 difficulty score)
A 45-year-old man comes to the physician because of ...
Oxygen saturation

Block/Question (26.3 difficulty score)
A 13-year-old boy is brought to the physician by his mother ...
This will typically resolve within the next 12 to 18 months.

Block/Question (38.9 difficulty score)
A 57-year-old man has had hoarseness and difficulty ...
Area labeled ‘F’

Block/Question (37.0 difficulty score)
A 55-year-old man is diagnosed with coronary artery disease. ...
Decreased adherence

Block/Question (26.2 difficulty score)
A 50-year-old woman is admitted to the hospital for ...
Factitious disorder

Block/Question (26.1 difficulty score)
A 75-year-old man with a 10-year history of progressive renal ...
Hydrostatic pressure in Bowman space

Block/Question (17.5 difficulty score)
A 17-year-old girl is brought to the hospital by ambulance 45 ...
Beneficence

Block/Question (47.7 difficulty score)
In which of the following stages of the cell cycle are ...
G2

Block/Question (25.2 difficulty score)
A 29-year-old man is brought to the emergency department ...
Lateral pterygoid

Block/Question (26.6 difficulty score)
A public health consultant is contacted by a health ...
Regular exercise

Block/Question (40.5 difficulty score)
An 80-year-old man is admitted to the hospital because of a ...
20

Block/Question (40.7 difficulty score)
An 80-year-old woman, gravida 4, para 4, comes to the office ...
Damage to the rectovaginal septum

Block/Question (14.2 difficulty score)
A 25-year-old man comes to the emergency department because ...
Heroin

Block/Question (29.2 difficulty score)
An investigator is studying a new drug for the treatment of ...
Free radical formation

Block/Question (24.1 difficulty score)
A 28-year-old man with chronic hepatitis C comes to the ...
HIV

Block/Question (20.8 difficulty score)
A 68-year-old man comes to the physician because he is ...
Normal aging

Block/Question (32.3 difficulty score)
A 68-year-old man has loss of pain and temperature sensations ...
Right dorsolateral medulla

Block/Question (25.8 difficulty score)
A 70-year-old man comes to the physician because of a 1-year ...
Alveolar-arterial Po 2 difference

Block/Question (36.1 difficulty score)
A 52-year-old man is admitted to the hospital for treatment ...
Granulation tissue

Block/Question (24.6 difficulty score)
A 50-year-old woman with HIV infection comes to the physician ...
Zidovudine

Block/Question (26.1 difficulty score)
A 3-month-old boy is brought to the physician because of ...
Peroxisomes

Block/Question (23.9 difficulty score)
A 9-year-old boy who was adopted from an African country 2 ...
E

Block/Question (15.9 difficulty score)
A 59-year-old man has repeated episodes of gouty arthritis ...
Probenecid

Block/Question (39.9 difficulty score)
A 35-year-old African American man comes to the physician for ...
Palms

Block/Question (49.5 difficulty score)
A 35-year-old man is brought to the emergency department ...
Catecholamine-mediated intracellular shifts of K+

Block/Question (24.7 difficulty score)
A 47-year-old man comes to the physician because of recurrent ...
Monosodium urate

Block/Question (16.2 difficulty score)
A 3-year-old boy with AIDS develops giant cell pneumonia 3 ...
Negative-stranded RNA

Block/Question (41.0 difficulty score)
A 65-year-old woman with well-controlled type 2 diabetes ...
Atherosclerosis

Block/Question (29.0 difficulty score)
A 35-year-old man with small cell carcinoma of the lung has ...
ACTH

Block/Question (14.0 difficulty score)
A patient with cancer who is being treated with high-dose ...
Granulocyte colony-stimulating factor

Block/Question (26.9 difficulty score)
A 35-year-old woman undergoes a left oophorectomy because of ...
Ureter

Block/Question (18.6 difficulty score)
A 58-year-old man comes to the physician because of a 3-day ...
Escherichia coli

Block/Question (36.2 difficulty score)
A 40-year-old man who goes horseback riding 3 to 4 times ...
Myositis ossificans

Block/Question (38.0 difficulty score)
A 55-year-old woman comes to the physician because of a ...
Lower motoneurons

Block/Question (24.4 difficulty score)
A 27-year-old woman comes to the physician for a follow-up ...
Transforming growth factor-β

Block/Question (30.8 difficulty score)
In a culture of motile spore-forming bacteria, which of the ...
Irradiation with x-rays

Block/Question (22.0 difficulty score)
A 65-year-old man comes to the physician because of ...
Paroxetine

Block/Question (15.6 difficulty score)
A 3-year-old boy has short stature and extremities and a ...
Endochondral ossification

Block/Question (35.6 difficulty score)
A 4-year-old boy has a 1-cm round midline mass just inferior ...
Tongue

Block/Question (11.8 difficulty score)
A 56-year-old man who is admitted to the hospital for ...
Determine whether the patient has decision-making capacity

Block/Question (42.1 difficulty score)
A 3-week-old female newborn is brought to the physician for a ...
The patient has another mutation that was not included in the previous analysis

Block/Question (22.9 difficulty score)
A 35-year-old woman has difficulty urinating 2 days post ...
Parasympathomimetic stimulation

Block/Question (23.5 difficulty score)
A 35-year-old man with quadriplegia develops a urinary tract ...
Area labeled ‘B’ (Proximal convoluted tubule)

Block/Question (34.3 difficulty score)
A 2-year-old boy is brought to the physician because of ...
Peptide transporter (TAP)

Block/Question (18.7 difficulty score)
In a study of drug action on neoplastic cells in culture, ...
Vincristine

Block/Question (16.7 difficulty score)
A 73-year-old man has an incurable malignant neoplasm of the ...
Both legal and ethical

Block/Question (67.8 difficulty score)
The breakdown of dipeptides and tripeptides to free amino ...
Intestinal mucosa

Block/Question (38.0 difficulty score)
A 17-year-old girl comes to the physician because she has ...
Increased serum testosterone concentration

Block/Question (26.7 difficulty score)
An obese 57-year-old man comes to the physician for a routine ...
Normal ciliated columnar epithelium replaced by normal squamous epithelium

Block/Question (17.0 difficulty score)
A 3-year-old girl has a history of recurrent infections. In ...
NADPH oxidase

Block/Question (46.1 difficulty score)
A 28-year-old man has a blood pressure cuff placed around his ...
Adenosine

Block/Question (28.9 difficulty score)
A 37-year-old woman with HIV infection is brought to the ...
Nucleoside reverse transcriptase inhibitor

Block/Question (29.3 difficulty score)
A 27-year-old man comes to the physician because he and his ...
Injections of gonadotropins

Block/Question (22.9 difficulty score)
A 37-year-old man is admitted to the hospital because of ...
Autoimmune adrenalitis

Block/Question (22.2 difficulty score)
A 43-year-old woman comes to the physician because of a ...
Alkaline phosphatase

Block/Question (23.6 difficulty score)
A 21-year-old woman with asthma comes to the physician ...
Phase 3

Block/Question (40.0 difficulty score)
A 37-year-old man who is a farmworker comes to the emergency ...
Synaptobrevin

Block/Question (27.1 difficulty score)
A 43-year-old woman comes to the physician because of a ...
Metastatic carcinoma

Block/Question (17.8 difficulty score)
Serum cholesterol concentrations are measured as part of a ...
16%

Block/Question (30.6 difficulty score)
The pedigrees of patients with schizophrenia most closely ...
Diabetes mellitus, type 1

Block/Question (31.5 difficulty score)
A 35-year-old woman with asthma comes to the emergency ...
Thiabendazole

Block/Question (39.3 difficulty score)
An 83-year-old woman is brought to the physician by her ...
Discussion of the diagnosis with the patient privately

Block/Question (37.5 difficulty score)
A cohort study is done to evaluate the association between ...
0.05 < p < 1.0

Block/Question (30.1 difficulty score)
A 17-year-old girl has significant blood loss after being ...
δ-Aminolevulinate

Block/Question (41.3 difficulty score)
An 18-year-old woman is brought to the physician because of ...
Respiratory acidosis

Block/Question (20.5 difficulty score)
HOX genes play a role in embryogenesis through which of the ...
Regulation of transcription

Block/Question (20.1 difficulty score)
A 55-year-old man with alcoholism is brought to the emergency ...
Competitive inhibitor

Block/Question (38.7 difficulty score)
A 23-year-old primigravid woman at 22 weeks' gestation is ...
Ask the patient if she would allow the examination if her husband is present at all times

Block/Question (29.2 difficulty score)
A 33-year-old woman comes to the physician because of a ...
Defect in a cell membrane anchor protein

Block/Question (18.6 difficulty score)
A 7-year-old girl is brought to the emergency department (ED) ...
Factitious disorder imposed on another

Block/Question (22.1 difficulty score)
A 32-year-old woman recently diagnosed with AIDS is at ...
Epstein-Barr virus-induced brain lymphoma

Block/Question (39.6 difficulty score)
A 32-year-old woman comes to the physician because of pain ...
Buccinator

Block/Question (44.7 difficulty score)
A 3-month-old boy is brought to the emergency department ...
Gluconeogenesis

Block/Question (55.9 difficulty score)
An investigator is studying a new virus isolated from a ...
Coronavirus

Block/Question (21.5 difficulty score)
A 54-year-old man with a myocardial infarction becomes ...
Decrease in intracellular ATP concentrations

Block/Question (10.8 difficulty score)
A 27-year-old man who works from home as a software engineer ...
Avoidant

Block/Question (41.0 difficulty score)
A 22-year-old man is brought to the emergency department 30 ...
Area labeled ‘E’ (Cerebellum, posterior lobe)

Block/Question (22.4 difficulty score)
Drug X is given to a 25-year-old normal subject. This drug ...
Partial agonist at β-adrenergic receptors

Block/Question (16.1 difficulty score)
A 38-year-old woman comes to the physician because of ...
Intraductal papilloma

Block/Question (46.2 difficulty score)
A 65-year-old man is brought to the emergency department 30 ...
Systemic vascular resistance: increased;
Pulmonary vascular resistance: decreased;
Pulmonary capillary wedge pressure: increased


Block/Question (24.1 difficulty score)
A 15-year-old girl is brought to the physician because of a ...
CD8+ T lymphocytes

Block/Question (35.4 difficulty score)
A 12-year-old boy is brought to the physician by his mother ...
Nocturnal luteinizing hormone pulses

Block/Question (60.1 difficulty score)
An otherwise healthy 35-year-old man sustains a fracture of ...
Decreased blood volume

Block/Question (36.1 difficulty score)
A 4-year-old girl has a history of multiple bone fractures ...
Scar formation

Block/Question (21.5 difficulty score)
A 1-month-old male newborn is brought to the physician for a ...
Tyrosine

Block/Question (34.6 difficulty score)
A man accidentally touches the surface of a hot stove; 20 ...
Interendothelial gaps in venules

Block/Question (26.8 difficulty score)
A 55-year-old man comes to the physician because of a 2-week ...
Serum free thyroxine (FT4): increased;
Serum free triiodothyronine (FT3): increased;
Thyroidal iodine uptake: decreased


Block/Question (31.6 difficulty score)
A 34-year-old woman is brought to the emergency department 45 ...
Lunate

Block/Question (19.9 difficulty score)
A 2-year-old boy is brought to the emergency department ...
Polysaccharide protein conjugate vaccine

Block/Question (15.3 difficulty score)
A 30-year-old man develops tingling around the lips and mouth ...
Sodium

Block/Question (44.8 difficulty score)
Which of the following terms best describes the fibrous ...
Lamins

Block/Question (31.8 difficulty score)
A 35-year-old woman with a long-standing history of asthma ...
Infiltration of lymphocytes and monocytes

Block/Question (33.5 difficulty score)
A 62-year-old man comes to the physician for a follow-up ...
Serum gastrin

Block/Question (22.7 difficulty score)
A 59-year-old woman has a 10-year history of progressive ...
Neural crest cells

Block/Question (38.4 difficulty score)
A 15-year-old girl with cystic fibrosis has a mutation in the ...
Endoplasmic reticulum

Block/Question (20.0 difficulty score)
A 22-year-old woman comes to the physician for a follow-up ...
Intrauterine device

Block/Question (15.0 difficulty score)
A 62-year-old man comes to the physician because of a 2-month ...
Phantom limb pain

Block/Question (33.9 difficulty score)
A 20-year-old woman with asthma comes to the physician ...
Ask the roommate not to smoke in the apartment

Block/Question (21.9 difficulty score)
A group of physicians submits a report to a medical journal ...
Case series

Block/Question (15.3 difficulty score)
A 30-year-old woman comes to the physician for follow-up ...
Glycine and succinyl CoA

Block/Question (17.5 difficulty score)
A full-term male newborn has lethargy, poor feeding, and ...
Enzymatic reaction labeled ‘C’

Block/Question (47.9 difficulty score)
A 23-year-old woman is brought to the emergency department ...
Renal tubular acidosis

Block/Question (37.3 difficulty score)
A 63-year-old woman develops flank pain, tachycardia, and ...
ABO incompatibility

Block/Question (49.5 difficulty score)
A 45-year-old man comes to the physician because of a 3-day ...
Muscle biopsy

Block/Question (50.6 difficulty score)
A 68-year-old woman comes to the physician because of a ...
Inferior mesenteric and superior mesenteric

Block/Question (38.3 difficulty score)
A 3-year-old girl is brought to the physician for a ...
Spontaneous regression

Block/Question (53.4 difficulty score)
A 1-week-old newborn is brought to the physician because of ...
Organic acid metabolism disorder

Block/Question (44.2 difficulty score)
A 10-year-old boy who was adopted from the Democratic ...
Black fly

Block/Question (39.6 difficulty score)
A 60-year-old woman is receiving cisplatin therapy for ...
Hyporeflexia

Block/Question (32.0 difficulty score)
A 53-year-old woman comes to the physician because of a ...
Fixed cardiac output in spite of increased demand

Block/Question (26.4 difficulty score)
A 25-year-old woman takes an overdose of barbiturates and is ...
Extubate the patient and discontinue mechanical ventilation; make no attempt to do cardiopulmonary resuscitation in case of cardiac or respiratory failure

Block/Question (27.6 difficulty score)
A 90-year-old man has a 1-week history of constipation and ...
Incarcerated inguinal hernia

Block/Question (7.0 difficulty score)
A new screening test for colon cancer is done in 86 patients ...
118/124 = 95%

Block/Question (17.6 difficulty score)
A 15-month-old boy is brought to the physician by his mother ...
Migration

Block/Question (32.0 difficulty score)
A 24-year-old woman who has diffuse toxic goiter (Graves ...
Phosphate: increased;
Parathyroid hormone: decreased;
25-hydroxyvitamin D: normal


Block/Question (42.7 difficulty score)
A 63-year-old woman undergoes operative repair of a leaking ...
Decreased movement through the arachnoid villi

Block/Question (49.8 difficulty score)
A 64-year-old man undergoes surgical repair of an abdominal ...
Artery of the ductus deferens

Block/Question (31.1 difficulty score)
A 38-year-old woman, gravida 4, para 4, comes to the ...
Internal anal sphincter

Block/Question (16.0 difficulty score)
Forty of 100 attendees at a company Christmas party develop ...
Vibrio parahaemolyticus

Block/Question (26.6 difficulty score)
An otherwise healthy 45-year-old man comes to the office ...
Aphthous ulcers

Block/Question (26.8 difficulty score)
A 45-year-old man is brought to the emergency department 2 ...
Renal calculi in the left ureter

Block/Question (24.7 difficulty score)
At 2:00 am, after sleeping for 5 hours, a 32-year-old man ...
Phenylethanolamine N-methyltransferase

Block/Question (24.3 difficulty score)
A 13-year-old girl who has a 6-year history of type 1 ...
Discuss further the impact of the patient's illness on the family

Block/Question (11.5 difficulty score)
A 26-year-old man is brought to the emergency department 40 ...
Pericardial tamponade

Block/Question (54.7 difficulty score)
A 10-year-old girl is brought to the physician by her mother ...
Ovarian Sertoli-Leydig cells

Block/Question (46.6 difficulty score)
A 19-year-old man has had weakness of the muscles of his neck ...
Polyneuropathy

Block/Question (22.5 difficulty score)
A clinical study is designed to evaluate the association of ...
10%

Block/Question (27.5 difficulty score)
A 56-year-old man has a 3-year history of progressive memory ...
Presenilin

Block/Question (50.0 difficulty score)
An investigator is studying an outbreak of Escherichia coli ...
Only cookies are independently associated with E. coli cases

Block/Question (38.8 difficulty score)
In a study of antibiotic resistance, a strain of Escherichia ...
Conjugation

Block/Question (11.9 difficulty score)
A 45-year-old man with hypercholesterolemia (LDL 260 mg/dL) ...
Increased synthesis of LDL receptors

Block/Question (30.6 difficulty score)
A 12-year-old boy is brought to the physician by his mother ...
Inhalant abuse

Block/Question (41.7 difficulty score)
A 55-year-old woman comes to the physician for a routine ...
Neuroendocrine cell

Block/Question (58.8 difficulty score)
An investigator is conducting a study of a novel protein in ...
Basal keratinocyte:suprabasal keratinocyte

Block/Question (19.2 difficulty score)
A 68-year-old woman comes to the emergency department 2 hours ...
Alendronate

Block/Question (25.8 difficulty score)
A male newborn is delivered in the hospital at 40 weeks' ...
Ingestion of undercooked meat

Block/Question (45.0 difficulty score)
A 33-year-old woman at 34 weeks' gestation has a grade 2/6 ...
Stroke volume

Block/Question (32.4 difficulty score)
A 30-year-old woman comes to the physician because of a ...
Decreased afferent arteriolar resistance

Block/Question (42.1 difficulty score)
A 25-year-old woman is brought to the emergency department by ...
Pulmonary capillary leakage

Block/Question (53.3 difficulty score)
A 30-year-old man who is a migrant farm worker comes to the ...
Formation of hypnozoites

Block/Question (34.0 difficulty score)
A 40-year-old man who recently immigrated to the USA from ...
Adenine

Block/Question (40.4 difficulty score)
A 72-year-old woman with coronary artery disease comes to the ...
Neointima formation in the right coronary stent

Block/Question (28.9 difficulty score)
A 71-year-old woman with non-Hodgkin lymphoma is diagnosed ...
Leucovorin

Block/Question (20.2 difficulty score)
A 40-year-old woman with a 25-year history of type 1 diabetes ...
Secreted by the proximal tubule

Block/Question (25.8 difficulty score)
A 22-year-old woman comes to the physician because of nausea ...
Pineal gland

Block/Question (18.0 difficulty score)
A 40-year-old man comes to the physician because of a 6-month ...
HNPCC syndrome

Block/Question (40.4 difficulty score)
A 55-year-old woman is brought to the physician by her ...
Posterior cerebral

Block/Question (48.6 difficulty score)
A 27-year-old man sustains a spinal cord transection at C-8 ...
Penile stimulation

Block/Question (19.7 difficulty score)
A 47-year-old man comes to the physician because of abdominal ...
Superior rectal vein

NBME 23

Block/Question (44.5 difficulty score)
An asymptomatic 30-year-old woman comes to the physician for ...
Anovulation

Block/Question (18.0 difficulty score)
A 56-year-old woman comes to the physician for a health ...
Microbial oncoprotein that interferes with tumor suppressor proteins

Block/Question (34.8 difficulty score)
A 52-year-old man comes to the physician because of severe ...
Triglyceride

Block/Question (29.0 difficulty score)
A male newborn has a myelomeningocele that involves the ...
Closure of the caudal neuropore

Block/Question (17.9 difficulty score)
A study is conducted to examine the effectiveness of a newly ...
Phase 2

Block/Question (16.4 difficulty score)
A 32-year-old woman comes to the emergency department after ...
Borderline

Block/Question (33.5 difficulty score)
Which of the following is present in integral plasma ...
Transmembrane region

Block/Question (23.6 difficulty score)
A 30-year-old man with HIV infection comes to the office for ...
It increases plasma concentrations of other PIs also metabolized by cytochrome P450

Block/Question (11.5 difficulty score)
A 45-year-old man is brought to the physician by his parents ...
Schizotypal

Block/Question (47.6 difficulty score)
A 13-year-old girl is brought to the office because of a ...
Staphylococcus aureus

Block/Question (33.1 difficulty score)
A 55-year-old man who has a 10-year history of type 2 ...
Impotence

Block/Question (24.4 difficulty score)
A 48-year-old man who is a farmer in a remote area of India ...
Blockade of postsynaptic inhibition of spinal motor reflexes

Block/Question (35.8 difficulty score)
A researcher is asked to prospectively investigate the ...
Prevalence: above the standard; Incidence: above the standard

Block/Question (16.0 difficulty score)
A 65-year-old woman develops deep venous thrombosis of the ...
Heparin-induced thrombocytopenia

Block/Question (17.3 difficulty score)
A 26-year-old man who is a Peace Corps volunteer comes to the ...
0.9% Saline

Block/Question (55.7 difficulty score)
Physical analysis of the isolated genomic DNA from a mutant ...
Methylase

Block/Question (40.9 difficulty score)
A 54-year-old woman comes to the physician because of a ...
Supraspinatus

Block/Question (26.4 difficulty score)
A 15-year-old boy has nasal polyps and develops bronchospasms ...
Enzyme B

Block/Question (35.0 difficulty score)
Unlike the DNA polymerases found in Escherichia coli, RNA ...
Mistakes in transcription are not transmitted to progeny

Block/Question (24.7 difficulty score)
A 22-year-old woman at 12 weeks' gestation comes to the ...
Hydropic villi with central cisterns

Block/Question (36.8 difficulty score)
A 40-year-old woman with a history of low-grade follicular ...
Bacterial pneumonia

Block/Question (41.6 difficulty score)
An investigator is studying the adverse effects of a ...
Presentation of antigens to CD8+ T lymphocytes

Block/Question (27.3 difficulty score)
A 35-year-old man comes to the physician because of a tremor ...
Anticholinergic agent

Block/Question (27.5 difficulty score)
A 39-year-old man comes to the physician because of darkening ...
Ferritin

Block/Question (37.1 difficulty score)
A 5-year-old boy who is undergoing induction chemotherapy for ...
Varicella-zoster virus

Block/Question (27.5 difficulty score)
A couple comes to the physician for counseling prior to ...
1/150

Block/Question (23.0 difficulty score)
An 11-year-old boy is brought to the physician by his mother ...
Sexual abuse

Block/Question (41.0 difficulty score)
An otherwise healthy 82-year-old man is brought to the ...
Posterior cord syndrome

Block/Question (34.4 difficulty score)
A 34-year-old woman with a 5-year history of hepatitis C ...
Infiltration of lymphocytes, plasma cells, and macrophages

Block/Question (26.5 difficulty score)
A 52-year-old man comes to the physician because of inability ...
Pelvic splanchnics

Block/Question (31.0 difficulty score)
A 16-month-old boy is brought to the physician for a ...
Absence of germinal centers in lymph nodes

Block/Question (17.6 difficulty score)
Which of the following sets of serum findings is most likely ...
Phosphate: increased;
Ca2+: decreased;
Parathyroid hormone: increased


Block/Question (47.3 difficulty score)
A 25-year-old woman and her 25-year-old husband come to the ...
α-Thalassemia trait

Block/Question (35.1 difficulty score)
A 64-year-old woman is found dead at the foot of her basement ...
Metastatic breast cancer

Block/Question (30.4 difficulty score)
A 42-year-old woman comes to the physician because of a ...
Binding of permeable ligand to nuclear transcription factor

Block/Question (23.1 difficulty score)
A medical student is caring for a 72-year-old man who has ...
Let me get the resident physician so we can go over the results.

Block/Question (29.5 difficulty score)
A 47-year-old woman with multiple sclerosis is brought to the ...
Fasciculus gracilis

Block/Question (21.6 difficulty score)
A 43-year-old woman sustains multiple fractures and ...
Hyaline membranes

Block/Question (27.8 difficulty score)
A 65-year-old man who is a farmer comes to the physician ...
Disruption of DNA strands secondary to ionization effect

Block/Question (22.7 difficulty score)
Which of the following properties of integral membrane ...
Extensive hydrophobic interactions between the amino acid side chains of the protein and the membrane phospholipid tails

Block/Question (36.9 difficulty score)
A 62-year-old woman is brought to the emergency department 30 ...
Pons

Block/Question (38.6 difficulty score)
A 68-year-old woman comes to the office because of a 3-month ...
Retroperitoneal fibrosis

Block/Question (33.5 difficulty score)
A 65-year-old woman has the recent appearance of a lesion at ...
Adenocarcinoma

Block/Question (26.8 difficulty score)
A 34-year-old woman is brought to the emergency department 30 ...
Area labeled ‘D’ (Spinothalamic tract, right)

Block/Question (20.1 difficulty score)
A 56-year-old woman comes to the physician because of a ...
Presynaptic release of acetylcholine

Block/Question (14.2 difficulty score)
A 31-year-old primigravid woman at 28 weeks' gestation comes ...
Bone

Block/Question (27.4 difficulty score)
A 61-year-old man comes to the emergency department because ...
Budd-Chiari syndrome

Block/Question (40.4 difficulty score)
A 20-year-old man is brought to the emergency department by ...
3,4-Methylenedioxymethamphetamine (MDMA)

Block/Question (54.2 difficulty score)
Electrical stimulation of the stellate ganglion is most ...
Heart rate

Block/Question (35.4 difficulty score)
A 45-year-old woman with coronary artery disease and anemia ...
4.5

Block/Question (27.3 difficulty score)
A 26-year-old woman comes to the physician because of a ...
Tinea corporis

Block/Question (40.4 difficulty score)
Cyclophosphamide and some other chemotherapeutic agents kill ...
Granulocytes

Block/Question (40.0 difficulty score)
A prospective study is done to assess the relative efficacy ...
Include the outcome for each participant in the group to which he or she was randomized

Block/Question (50.9 difficulty score)
An 18-year-old woman comes to the physician because of a ...
Maximum oxygen consumption (VO2max): decreased;
Venous blood lactate: increased;
Energy production by glycolysis: increased


Block/Question (31.5 difficulty score)
A female newborn develops respiratory distress. Her ...
Osteogenesis imperfecta, type I

Block/Question (32.4 difficulty score)
A 6-month-old girl is brought to the office for a well-child ...
Hepatitis B

Block/Question (40.2 difficulty score)
A 45-year-old man is brought to the emergency department ...
Hypovolemic shock

Block/Question (26.0 difficulty score)
An 8-year-old boy is brought to the physician by his mother 6 ...
Serum calcitonin concentration

Block/Question (26.5 difficulty score)
A 60-year-old man has had easy fatigability, loss of ...
Lung

Block/Question (26.2 difficulty score)
A 50-year-old man who lives in eastern Minnesota comes to the ...
Babesia microti and Borrelia burgdorferi

Block/Question (18.3 difficulty score)
An antiserum is elicited by immunization with protein X, and ...
Proteins X and Y have no epitopes in common

Block/Question (29.1 difficulty score)
A 75-year-old woman has stress urinary incontinence with ...
Stimulation of α-adrenoreceptors

Block/Question (28.4 difficulty score)
A 45-year-old man comes to the office for a health ...
Invasion of the submucosa

Block/Question (8.7 difficulty score)
A 65-year-old woman with diabetic ketoacidosis has had a ...
Mucormycosis

Block/Question (68.7 difficulty score)
A child with septicemia has an antibiotic clearance (Cl) of ...
28.8

Block/Question (55.7 difficulty score)
Which of the following best explains impaired action ...
Increase in axonal capacitance

Block/Question (22.4 difficulty score)
A 21-year-old man comes to the physician because of a 1-month ...
Leishmania

Block/Question (18.8 difficulty score)
A 48-year-old man comes to the physician because of a 24-hour ...
Perforated peptic ulcer

Block/Question (43.4 difficulty score)
A 70-year-old man with severe congestive heart failure has ...
Serum BUN: 40;
Serum creatinine: 2;
Urine Na+: 5;
Urine specific gravity: 1.025


Block/Question (28.7 difficulty score)
A 47-year-old woman has had a goiter for 10 months. She has ...
Replacement of thyroid parenchyma by lymphoid cells

Block/Question (29.9 difficulty score)
A 55-year-old man comes to the physician because of a 1-year ...
FEV1/FVC: normal;
FVC: decreased;
Diffusing capacity of the lung for carbon monoxide: decreased


Block/Question (28.6 difficulty score)
A 42-year-old man comes to the physician because of a 1-month ...
Sand fly

Block/Question (21.3 difficulty score)
A 75-year-old man with prostate cancer has metastases to the ...
Prostatic venous plexus to the vertebral venous plexus

Block/Question (28.4 difficulty score)
A 46-year-old woman has a 1-day history of high-grade fever, ...
Leukocyte alkaline phosphatase activity greater than 250 U/L

Block/Question (42.7 difficulty score)
A 44-year-old man with invasive pancreatic cancer is brought ...
Area labeled ‘H’

Block/Question (26.3 difficulty score)
A 36-year-old woman comes to the physician for a follow-up ...
Fibromuscular dysplasia

Block/Question (27.0 difficulty score)
A 3-month-old girl is brought to the physician by her parents ...
Densely packed capillaries

Block/Question (34.8 difficulty score)
A cohort study is conducted to examine the association ...
200

Block/Question (19.5 difficulty score)
Which of the following pairs of drugs interferes with DNA ...
Lomustine and cyclophosphamide

Block/Question (37.7 difficulty score)
A 21-year-old man is brought to the emergency department 30 ...
Liver

Block/Question (7.4 difficulty score)
A 40-year-old man has had enlarging breast tissue for the ...
Spironolactone

Block/Question (64.1 difficulty score)
A 2-year-old girl is brought to the physician because she is ...
N-methyl-d-aspartate (NMDA)

Block/Question (51.0 difficulty score)
A 68-year-old man who has been treated for the past 4 weeks ...
Area labeled ‘B’

Block/Question (24.9 difficulty score)
A 35-year-old woman comes to the physician because of a ...
Synthesis of viral DNA

Block/Question (21.1 difficulty score)
A 42-year-old man with a history of recurrent pyelonephritis ...
Magnesium ammonium phosphate

Block/Question (23.1 difficulty score)
A newborn has external genitalia that appear to be male. ...
Hyperplastic fetal adrenal glands

Block/Question (15.1 difficulty score)
A 62-year-old woman is brought to the physician because her ...
Embolus to the femoral artery with left leg ischemia

Block/Question (29.6 difficulty score)
A 78-year-old man is found unresponsive in his yard by a ...
"Thank you for telling me this. Your friend's previous statements to you can be helpful in making decisions for him."

Block/Question (35.9 difficulty score)
A 39-year-old woman with obesity and recently diagnosed ...
Gemfibrozil

Block/Question (40.9 difficulty score)
A 22-year-old man is brought to the emergency department 30 ...
Peak inspiratory pressure (alveolar): positive;
End-tidal pressure (alveolar): positive;
Peak inspiratory pressure (intrapleural): positive;
End-tidal pressure (intrapleural): positive


Block/Question (33.7 difficulty score)
A 44-year-old woman, gravida 2, para 2, comes to the ...
Cervical canal

Block/Question (49.9 difficulty score)
A 63-year-old woman comes to the physician because of a ...
FVC: decreased;
FEV1/FVC: decreased;
Peak expiratory flow rate: decreased;
Peak inspiratory flow rate: decreased


Block/Question (39.9 difficulty score)
A 2-week-old girl is brought to the physician by her parents ...
Iris

Block/Question (47.0 difficulty score)
A 4-year-old boy is brought to the physician by his parents ...
Dietary change

Block/Question (20.3 difficulty score)
A 61-year-old man is prescribed fluoxetine for major ...
Raphe nuclei

Block/Question (11.3 difficulty score)
Which of the following types of vaccine is most appropriate ...
Live attenuated virus

Block/Question (28.4 difficulty score)
A 65-year-old man is scheduled for physical therapy 3 days ...
Medial (internal) rotation

Block/Question (22.6 difficulty score)
A 45-year-old woman is brought to the emergency department ...
Inspiratory pause on right upper quadrant palpation

Block/Question (29.4 difficulty score)
A 56-year-old man comes to the physician because of severe ...
Colchicine

Block/Question (10.8 difficulty score)
A 65-year-old man recovering from a cerebral infarction due ...
Preventing ADP-stimulated platelet activation

Block/Question (42.7 difficulty score)
A 32-year-old woman comes to the physician after the result ...
Yolk sac

Block/Question (29.8 difficulty score)
A 35-year-old man comes to a new physician for a health ...
Liver

Block/Question (31.9 difficulty score)
An 18-hour-old male newborn is 61 cm (24 in) long and weighs ...
Decreased gluconeogenesis

Block/Question (63.1 difficulty score)
A 31-year-old primigravid woman at 32 weeks' gestation comes ...
Hypoglycemia

Block/Question (17.5 difficulty score)
A 68-year-old woman has a 6-month history of weakness, ...
Na+: decreased;
K+: increased;
pH: decreased


Block/Question (34.0 difficulty score)
A 25-year-old man has an orchiectomy for a recently detected ...
Germ cells

Block/Question (11.0 difficulty score)
A male newborn is delivered at 39 weeks' gestation after an ...
Gastroschisis

Block/Question (24.3 difficulty score)
A 62-year-old man with a blood pressure of 220/160 mm Hg ...
Labetalol

Block/Question (21.9 difficulty score)
A male newborn is delivered at term to a 30-year-old woman. ...
Ask the mother and sister to leave the room and inform the parents of the abnormality

Block/Question (26.6 difficulty score)
An investigator is studying two drugs, Drugs X and Y, to ...
Area under the curve

Block/Question (12.9 difficulty score)
A 50-year-old woman with idiopathic cardiomyopathy is ...
Penetration of larvae from soil into the skin

Block/Question (21.6 difficulty score)
A 39-year-old man comes to the physician for a routine health ...
β-Myosin

Block/Question (33.3 difficulty score)
A 65-year-old man with a history of gout comes to the ...
I will authorize the permit, but I recommend that you continue with regular exercise and only use the permit when you are having severe pain.

Block/Question (14.2 difficulty score)
A 3-day-old male infant with Down syndrome has had repeated ...
Duodenal atresia

Block/Question (22.4 difficulty score)
A 45-year-old woman comes to the physician for a follow-up ...
Myopathy

Block/Question (23.2 difficulty score)
A 40-year-old woman comes to the physician because of a ...
Pituitary gland

Block/Question (39.9 difficulty score)
A 24-year-old woman comes to the physician because of a ...
Accessory spleen

Block/Question (35.2 difficulty score)
A patient with a 20-year history of type 1 diabetes mellitus ...
Impaired release of glucagon

Block/Question (38.5 difficulty score)
A previously healthy 32-year-old man is brought to the ...
Toxicology screening

Block/Question (24.2 difficulty score)
An 82-year-old woman is brought to the physician by her ...
Decreased function of the puborectalis muscle

Block/Question (31.2 difficulty score)
A 60-year-old woman comes to the physician 1 week after she ...
Amplification

Block/Question (32.7 difficulty score)
A 54-year-old woman with rheumatic heart disease is brought ...
Intra-alveolar transudates

Block/Question (25.4 difficulty score)
A pregnant 28-year-old woman is found to have symmetrical ...
Lactotrope

Block/Question (39.7 difficulty score)
A 25-year-old man is brought to the emergency department 30 ...
Fractional excretion of sodium greater than 2%

Block/Question (26.1 difficulty score)
A 43-year-old woman undergoing chemotherapy for acute ...
Preformed IgM antibodies

Block/Question (24.5 difficulty score)
A 27-year-old woman has headaches and blurred vision. She ...
Angiotensin

Block/Question (18.3 difficulty score)
A 30-year-old man reports increasing fatigue and dyspnea on ...
Atrial septal defect

Block/Question (23.6 difficulty score)
A 10-year-old boy sustains an abrasion on his left knee. One ...
Labile cells

Block/Question (26.2 difficulty score)
A 50-kg (110-lb) experimental animal receives 1 L of 5% ...
Intracellular volume: decreased;
Intracellular osmolality: increased;
Extracellular volume: increased;
Extracellular osmolality: increased


Block/Question (37.4 difficulty score)
A 20-year-old woman comes to the physician because of a ...
C1q

Block/Question (11.7 difficulty score)
The parents of a 1-year-old boy with a bilateral cleft palate ...
Multifactorial

Block/Question (22.9 difficulty score)
A 70-year-old man comes to the physician because of decreased ...
Inhibition of prostaglandin synthesis

Block/Question (37.1 difficulty score)
A 78-year-old man has had progressive loss of hearing in his ...
Otosclerosis

Block/Question (18.8 difficulty score)
A 34-year-old woman with a long-standing history of ...
Fat

Block/Question (20.2 difficulty score)
A 31-year-old woman comes to the emergency department because ...
Tell the patient's husband that he is not allowed in the treatment area, and that he must remain in the waiting area

Block/Question (36.2 difficulty score)
A 70-year-old woman comes to the physician because of a ...
Serum sickness

Block/Question (25.8 difficulty score)
A 48-year-old man is referred for evaluation of possible ...
108 to 118

Block/Question (41.4 difficulty score)
A 5-year-old boy who has recently recovered from an upper ...
Immune destruction of platelets

Block/Question (34.5 difficulty score)
A 44-year-old woman comes to the physician because of a ...
Decreased CSF production by the choroid plexus

Block/Question (16.7 difficulty score)
A 38-year-old woman with hypercalcemia, hypophosphatemia, and ...
Area labeled ‘B’ (Proximal convoluted tubule)

Block/Question (23.3 difficulty score)
A previously healthy 45-year-old man comes to the physician ...
Infraspinatus

Block/Question (13.0 difficulty score)
A 48-year-old woman has severe gastroesophageal reflux. ...
Inhibition of gastric H+–K+ ATPase

Block/Question (13.3 difficulty score)
A 65-year-old man has had increasing shortness of breath over ...
Osteitis deformans (Paget disease)

Block/Question (25.4 difficulty score)
A 23-year-old woman comes to the physician for advice ...
Because irradiated food is not radioactive, you will not be exposed to ionizing radiation by consuming it.

Block/Question (25.4 difficulty score)
A 44-year-old woman comes to the physician because of a ...
Decreased arterial Pco2

Block/Question (43.0 difficulty score)
A 19-year-old woman is severely burned over 35% of her total ...
Increased metabolic rate

Block/Question (15.8 difficulty score)
A 14-year-old boy with a tibial fracture is fitted with a leg ...
Neck of the fibula

Block/Question (34.9 difficulty score)
A 20-year-old woman comes to the physician because of a ...
Inhibition of the cytochrome P450-dependent demethylation reaction

Block/Question (22.7 difficulty score)
Genetic analyses of cells obtained on amniocentesis confirm ...
Epinephrine

Block/Question (36.0 difficulty score)
A 32-year-old woman, gravida 2, para 1, at 39 weeks' ...
Increased fetal systemic vascular resistance

Block/Question (44.1 difficulty score)
A 65-year-old man is brought to the emergency department ...
Thromboxane A2

Block/Question (47.6 difficulty score)
A 60-year-old woman with type 2 diabetes mellitus comes to ...
Subacromial bursitis

Block/Question (24.1 difficulty score)
A 33-year-old woman comes to the physician for a routine ...
Inorganic phosphorus: decreased;
Parathyroid hormone: increased;
Calcitriol: decreased


Block/Question (16.7 difficulty score)
A 76-year-old woman is brought to the physician by her son ...
She expresses clear and consistent values

Block/Question (17.3 difficulty score)
Transmission of a bacterial agent by person-to-person contact ...
Meningococcal meningitis

Block/Question (24.4 difficulty score)
A 35-year-old woman, gravida 2, para 1, undergoes vaginal ...
External anal sphincter

Block/Question (14.1 difficulty score)
A 3-day-old female newborn delivered at term is brought to ...
Increased conversion of bilirubin to water-soluble isomers

Block/Question (23.0 difficulty score)
A 36-year-old nulligravid woman and her 40-year-old husband ...
1 of 50

Block/Question (15.8 difficulty score)
A 35-year-old man who is a veterinarian in a rural area comes ...
Coxiella burnetii

Block/Question (36.7 difficulty score)
A study was conducted to investigate the mean age at onset in ...
99%

Block/Question (15.5 difficulty score)
A 40-year-old man comes to the physician for a routine health ...
Finasteride

Block/Question (43.1 difficulty score)
Investigators conduct a prospective, community-based study to ...
Strength of association, temporal relationship, dose-response gradient

Block/Question (31.8 difficulty score)
A 65-year-old man comes to the physician because of a 1-year ...
Smooth muscle cells of the deep artery

Block/Question (41.3 difficulty score)
A 61-year-old woman comes to the physician for a health ...
Closure of the mitral valve

Block/Question (33.3 difficulty score)
A 35-year-old man comes to the physician because of a 4-month ...
Arachidonic acid

Block/Question (22.6 difficulty score)
In a study of the use of ultrasonography for the early ...
80%

Block/Question (19.3 difficulty score)
A 24-year-old man has a grade 3/6 systolic murmur. Cardiac ...
Aortic stenosis

Block/Question (43.0 difficulty score)
An investigator is conducting a study to determine the cause ...
Enveloped

Block/Question (24.4 difficulty score)
A 6-month-old male infant is brought to the physician because ...
Regulatory T lymphocytes

Block/Question (28.9 difficulty score)
A 7-year-old boy is brought to the physician by his mother ...
Release of interferon gamma by TH1 cells

Block/Question (24.5 difficulty score)
An otherwise healthy 26-year-old scuba diver has difficulty ...
Hyperresonance over most of the left side of the chest

Block/Question (21.4 difficulty score)
A 40-year-old man with terminal small cell carcinoma of the ...
Demeclocycline

Block/Question (33.8 difficulty score)
A 74-year-old woman comes to the physician because of a ...
Ipratropium

Block/Question (38.3 difficulty score)
A 60-year-old man comes to the physician because of a 1-month ...
Erythropoietin

Block/Question (14.2 difficulty score)
An 85-year-old woman is brought to the physician by her ...
Donepezil

Block/Question (21.3 difficulty score)
A 28-year-old man has hypertriglyceridemia that has not ...
Aspirin

Block/Question (34.5 difficulty score)
A man accidentally touches the surface of a hot stove; 20 ...
Histamine

Block/Question (53.1 difficulty score)
An 18-month-old girl is brought to the physician because of ...
Decreased sodium bicarbonate reabsorption in the proximal tubule

Block/Question (27.3 difficulty score)
A 2-week-old male newborn is brought to the physician by his ...
Galactose-1-phosphate uridyltransferase

Block/Question (18.3 difficulty score)
A study is planned to assess differences in hypertension ...
Cross-sectional study

Block/Question (38.5 difficulty score)
A 32-year-old man who lives at sea level travels to a ...
Normoblasts

Block/Question (43.5 difficulty score)
A 42-year-old woman comes to the office because of a 1-year ...
Spontaneous regression

Block/Question (56.2 difficulty score)
A 16-year-old girl with bulimia nervosa is brought to the ...
Potassium: decreased;
Chloride: increased;
Bicarbonate: decreased


Block/Question (21.0 difficulty score)
A 44-year-old man who is a farmer and has been spraying his ...
Area labeled ‘D’

Block/Question (13.5 difficulty score)
A 17-year-old girl with type 1 diabetes mellitus comes to the ...
Acknowledge the patient's reasons for missing insulin injections

Block/Question (20.2 difficulty score)
A 40-year-old man comes to the physician because of a 3-month ...
Postcentral

Block/Question (26.8 difficulty score)
A 2-year-old boy is brought to the emergency department ...
Lipoprotein lipase

Block/Question (14.5 difficulty score)
A 45-year-old woman is scheduled to undergo a lymph node ...
Accompany the resident while the resident obtains signed consent

Block/Question (46.9 difficulty score)
A 44-year-old woman comes to the physician because of ...
Celiac sprue

Block/Question (27.0 difficulty score)
A 16-year-old girl is brought to the emergency department 30 ...
Tail of the pancreas

Block/Question (50.2 difficulty score)
Electrophysiology of the heart is studied in an anesthetized ...
Ablation of the atrioventricular node

Block/Question (21.9 difficulty score)
A 12-year-old girl is admitted to the hospital for treatment ...
Methionine

Block/Question (22.8 difficulty score)
A 65-year-old man develops a progressive ataxia with gait ...
Right cerebellar hemisphere

Block/Question (28.2 difficulty score)
A 44-year-old man is brought to the emergency department by ...
Entrapment of the inferior rectus muscle

Block/Question (74.5 difficulty score)
A 32-year-old man has a diastolic blood pressure that ...
Precapillary resistance

Block/Question (31.8 difficulty score)
A female neonate is delivered at 38 weeks' gestation by ...
Rough endoplasmic reticulum

Block/Question (30.7 difficulty score)
A 43-year-old woman comes to the physician because she has ...
Left atrial myxoma

Block/Question (25.9 difficulty score)
A 2-week-old female newborn of Mexican descent is brought to ...
Why don't you continue with what you're doing, and let's try changing her to a different formula.

Block/Question (25.4 difficulty score)
A 15-year-old boy is brought to the physician for a ...
Testosterone

Block/Question (39.3 difficulty score)
A 48-year-old man has complete loss of hearing in his right ...
Area labeled ‘C’ (Cranial nerve 8: vestibulocochlear)

NBME 22

Block/Question (85.2 difficulty score)
A 66-year-old man develops worsening shortness of breath and ...
Dilution of serum sodium due to ADH (vasopressin) secretion

Block/Question (44.7 difficulty score)
A 28-year-old man has recurrent pancreatitis associated with ...
Decreasing VLDL

Block/Question (29.7 difficulty score)
Parenterally administered cholera vaccines consisting of ...
Inability of the vaccine to elicit secretory antibody at the epithelial surface

Block/Question (38.2 difficulty score)
A 48-year-old man begins furosemide therapy for pedal edema ...
Decreases the luminal permeability to Na+ in the collecting duct

Block/Question (23.2 difficulty score)
A 10-month-old girl is brought to the emergency department ...
Naloxone

Block/Question (23.1 difficulty score)
A 2-month-old boy is brought to the physician because of a ...
Human papillomavirus

Block/Question (30.4 difficulty score)
Two patients, a 54-year-old man (Patient X) and a 76-year-old ...
Loading dose

Block/Question (30.2 difficulty score)
A 16-year-old girl has pain and tingling in her left hand ...
Cervical rib

Block/Question (47.0 difficulty score)
A 54-year-old man has an aneurysm in the distal portion of ...
2.4

Block/Question (15.8 difficulty score)
A 25-year-old woman is admitted to the hospital because of ...
Streptococcus pneumoniae

Block/Question (24.0 difficulty score)
A 6-month-old boy has recently been diagnosed with ...
Sphingomyelin degradation

Block/Question (15.3 difficulty score)
During the first week of life, a male newborn has vomiting, ...
21-Hydroxylase

Block/Question (17.9 difficulty score)
A 13-year-old girl is brought to the physician by her mother ...
Ask the mother to leave the room before asking the patient any questions

Block/Question (9.7 difficulty score)
A 57-year-old woman comes to the physician because of ...
Trigeminal neuralgia

Block/Question (46.2 difficulty score)
A 35-year-old woman has weakness and fever. When she was 25 ...
Acute myelocytic leukemia

Block/Question (30.0 difficulty score)
An Rh-negative woman, gravida 3, para 2, has had an ...
O, Rh-negative

Block/Question (43.3 difficulty score)
A 27-year-old man is brought to the emergency department ...
Eversion

Block/Question (36.2 difficulty score)
A 13-year-old boy is brought to the physician for a ...
Reassurance

Block/Question (21.5 difficulty score)
An 11-year-old boy has had pain in his right mid-thigh for 2 ...
Ewing sarcoma

Block/Question (53.1 difficulty score)
A 49-year-old man comes to the physician because of ...
Avascular necrosis

Block/Question (30.6 difficulty score)
A 30-year-old man comes to the physician because of a 2-day ...
Polycystin

Block/Question (24.7 difficulty score)
A previously healthy 6-year-old boy is brought to the ...
Does anyone else in the family have an itchy rash like this?

Block/Question (28.8 difficulty score)
A patient in the early stages of hemorrhagic shock is most ...
A weak pulse due to decreased stroke volume

Block/Question (32.4 difficulty score)
A 48-year-old man with renal artery stenosis undergoes stent ...
Testicular artery

Block/Question (41.9 difficulty score)
During an experiment, a 22-year-old man receives an infusion ...
Arteriolar resistance: decreased;
Capillary hydrostatic pressure: increased;
Capillary filtration rate: increased


Block/Question (36.0 difficulty score)
A 42-year-old man comes to the physician because of a 1-month ...
Hydrochlorothiazide

Block/Question (13.6 difficulty score)
During a clinical study, 15 patients with renal allografts ...
Azathioprine

Block/Question (26.9 difficulty score)
A 48-year-old man comes to the physician because of fatigue, ...
Transferrin saturation and serum ferritin measurements

Block/Question (49.5 difficulty score)
A 28-year-old man comes to the emergency department because ...
Jejunum

Block/Question (29.9 difficulty score)
A 42-year-old woman is brought to the emergency department by ...
Temporal lobe

Block/Question (22.9 difficulty score)
A 60-year-old woman comes to the physician because of a ...
Lung cancer

Block/Question (46.9 difficulty score)
A 17-year-old boy is brought to the emergency department 45 ...
Hypokalemia

Block/Question (24.9 difficulty score)
A 32-year-old woman begins to hyperventilate and then ...
Cerebral blood flow

Block/Question (20.1 difficulty score)
A 15-year-old girl is brought to the physician by her mother ...
First-degree burn

Block/Question (46.7 difficulty score)
A 35-year-old man is brought to the hospital after a diving ...
Alteration of the thermostatic set point

Block/Question (15.8 difficulty score)
A 67-year-old woman comes to the physician because of a ...
Idiopathic pulmonary fibrosis

Block/Question (53.1 difficulty score)
A 28-year-old woman is brought to the physician because of a ...
Area labeled ‘C’ (Abducens nucleus, right)

Block/Question (23.0 difficulty score)
A newborn born at 26 weeks' gestation has respiratory ...
Dipalmitoyl lecithin

Block/Question (17.8 difficulty score)
A 23-year-old woman develops multiple red, papulovesicular ...
Processing of antigen by Langerhans cells, leading to activation of CD4+ T cells

Block/Question (25.8 difficulty score)
A 45-year-old man with chronic pancreatitis caused by alcohol ...
Pancrelipase

Block/Question (36.1 difficulty score)
A 21-year-old man is brought to the emergency department 1 ...
Gender and body habitus

Block/Question (20.8 difficulty score)
An 18-year-old woman develops sepsis after an abortion. ...
Decreased plasma fibrinogen concentration

Block/Question (20.4 difficulty score)
A 13-year-old girl is brought to the emergency department 15 ...
C1 inhibitor

Block/Question (36.6 difficulty score)
A 52-year-old man with a history of alcoholic cirrhosis is ...
Superior rectal

Block/Question (51.9 difficulty score)
A 16-year-old girl is brought to the physician because of ...
Diuretics

Block/Question (18.9 difficulty score)
A 12-year-old girl is referred to the emergency department by ...
Conversion disorder

Block/Question (23.8 difficulty score)
A 25-year-old woman comes to the physician because of easy ...
Immune thrombocytopenic purpura

Block/Question (33.0 difficulty score)
A 1-year-old boy is found to have an impairment of the ...
Staphylococcus aureus

Block/Question (21.4 difficulty score)
A 17-year-old primigravid woman at 16 weeks' gestation has a ...
Azithromycin

Block/Question (28.9 difficulty score)
A 9-year-old boy is brought to the physician by his mother ...
Protein structure

Block/Question (47.6 difficulty score)
A 29-year-old woman is brought to the emergency department 1 ...
Avulsion of hepatic veins from the inferior vena cava

Block/Question (13.4 difficulty score)
A 65-year-old man starts using topical fluorouracil for ...
Thymidylate synthase

Block/Question (20.6 difficulty score)
A previously healthy 28-year-old man comes to the physician's ...
Nephrolithiasis

Block/Question (24.6 difficulty score)
A previously healthy 60-year-old woman is admitted to the ...
Increased central venous pressure

Block/Question (35.8 difficulty score)
A 74-year-old man with emphysema and lung cancer is brought ...
Negative nitrogen balance

Block/Question (34.0 difficulty score)
A 52-year-old man is brought to the emergency department 1 ...
4 Months

Block/Question (58.6 difficulty score)
A 66-year-old man comes to the physician because of a 2-month ...
Libido: decreased;
Nocturnal erections: normal


Block/Question (32.5 difficulty score)
A 73-year-old man has difficulty urinating and frequent ...
Area labeled ‘E’

Block/Question (34.5 difficulty score)
A 26-year-old woman develops hypotension and hemoglobinuria ...
Antibody, complement C5-9

Block/Question (25.4 difficulty score)
A 56-year-old man with a palpable hard nodule on the prostate ...
Pelvic parasympathetic nerves

Block/Question (55.7 difficulty score)
A 52-year-old man comes to the physician because a lump in ...
Sensation from the anterior surface of the scrotum

Block/Question (20.5 difficulty score)
A 42-year-old woman with frequent heartburn has relief of ...
cAMP

Block/Question (23.0 difficulty score)
A 5-year-old boy who lives on a farm has had diarrhea, ...
Yersinia enterocolitica

Block/Question (31.5 difficulty score)
A previously healthy 12-year-old boy is brought to the ...
Glucose and sodium

Block/Question (36.9 difficulty score)
A 62-year-old woman comes to the physician 3 days after ...
Carcinoma of the breast

Block/Question (19.3 difficulty score)
A 60-year-old man is brought to the emergency department ...
Prostate adenocarcinoma

Block/Question (14.9 difficulty score)
Ten healthy human subjects are given a new oral drug and ...
Phase 1

Block/Question (20.4 difficulty score)
A 32-year-old man comes to the physician because of a 2-week ...
Reverse transcriptase

Block/Question (22.3 difficulty score)
A 50-year-old man comes to the physician 3 days after his ...
Calcium

Block/Question (16.8 difficulty score)
A 26-year-old nulligravid woman comes to the physician ...
Hypothalamus

Block/Question (22.9 difficulty score)
A newborn has cyanosis, tachypnea, and retractions of the ...
Respiratory acidosis and metabolic acidosis

Block/Question (42.5 difficulty score)
A 35-year-old man comes to the physician because of a 3-year ...
Adenylyl cyclase

Block/Question (31.0 difficulty score)
A 32-year-old woman comes to the physician because of a 1-day ...
Reduviid bug

Block/Question (18.5 difficulty score)
A 72-year-old man is given ketorolac for pain control after ...
Acute renal failure

Block/Question (35.2 difficulty score)
A 37-year-old woman undergoes excision of a 1-cm, painless, ...
Angiogenesis

Block/Question (11.5 difficulty score)
A randomized controlled trial is conducted to assess the ...
(194/2371) – (123/2365)

Block/Question (26.8 difficulty score)
A 50-year-old man who has smoked 2 packs of cigarettes a day ...
Increased blood HCO3−

Block/Question (16.6 difficulty score)
A 65-year-old man comes to the physician for a follow-up ...
Ulnar and tibial

Block/Question (20.8 difficulty score)
A 79-year-old man is brought to the emergency department by ...
Insertion of transvenous pacemaker

Block/Question (24.9 difficulty score)
A 40-year-old woman comes to the physician because of a ...
Multifactorial

Block/Question (38.5 difficulty score)
An unimmunized 1-year-old boy is admitted to the hospital ...
Phase variation

Block/Question (45.4 difficulty score)
A 54-year-old man who works in a delicatessen comes to the ...
Schwann cells

Block/Question (26.6 difficulty score)
A 29-year-old woman comes to the physician because of a ...
Thyroid-stimulating hormone: decreased;
Free thyroxine: decreased;
Free triiodothyronine: increased


Block/Question (43.9 difficulty score)
A 30-year-old man and a 24-year-old woman (indicated by the ...
1 in 600

Block/Question (52.4 difficulty score)
A 45-year-old man with Li-Fraumeni syndrome agrees to ...
Decreased binding of RNA polymerase

Block/Question (32.5 difficulty score)
Which of the following drug effects is the most common reason ...
Anticholinergic

Block/Question (45.4 difficulty score)
A 63-year-old man has had progressive stiffness over the past ...
Area labeled ‘D’

Block/Question (25.6 difficulty score)
Following a stroke, a patient is hoarse and cannot detect ...
Lateral medulla

Block/Question (21.6 difficulty score)
A 22-year-old woman comes to the office because of a 3-day ...
Cardiomyopathy

Block/Question (22.1 difficulty score)
A previously healthy 7-year-old girl is brought to the ...
Serum potassium concentration

Block/Question (48.9 difficulty score)
A 12-year-old boy is swimming in a mountain stream. He is ...
Central blood volume: increased;
Serum ADH (vasopressin): decreased;
Serum atrial natriuretic peptide: increased


Block/Question (21.2 difficulty score)
A 75-year-old woman has taken 12 over-the-counter ...
Plasma renin activity

Block/Question (29.9 difficulty score)
A 20-year-old man comes to the physician because of tingling ...
Area labeled ‘C’

Block/Question (15.5 difficulty score)
A 3-day-old full-term male newborn is brought to the ...
Hepatic UDP-glucuronosyltransferase activity

Block/Question (43.0 difficulty score)
An 86-year-old man who lives in a skilled nursing care ...
Dextromethorphan

Block/Question (33.9 difficulty score)
A 62-year-old man is being evaluated for rectal bleeding. An ...
Greater mucosal surface area

Block/Question (12.5 difficulty score)
A 22-year-old woman who is at 16 weeks' gestation has ...
Down syndrome

Block/Question (12.6 difficulty score)
Clostridium perfringens-α toxin affects cells and facilitates ...
Splitting lecithin to phosphorylcholine and diglyceride

Block/Question (7.1 difficulty score)
A physician is unable to communicate "bad news" to a patient ...
Countertransference

Block/Question (32.0 difficulty score)
An 18-month-old boy is admitted to the hospital because of ...
Tuberous sclerosis complex

Block/Question (59.9 difficulty score)
A 35-year-old man comes to the physician because of a 6-week ...
C7 nerve root

Block/Question (24.6 difficulty score)
A 30-year-old man is brought to the emergency department 30 ...
Increased serum angiotensin II concentration

Block/Question (23.1 difficulty score)
An obese 45-year-old woman with type 2 diabetes mellitus, ...
Diarrhea

Block/Question (42.5 difficulty score)
A 29-year-old woman has an inflammatory disease involving her ...
Immune complex-mediated cytotoxicity

Block/Question (56.9 difficulty score)
A 72-year-old man with multiple myeloma agrees to participate ...
Unrearranged immunoglobulin gene

Block/Question (36.8 difficulty score)
A 50-year-old man is admitted to the hospital because of ...
Intracellular [Na+]: increased;
Intracellular [K+]: decreased;
Intracellular [Ca2+]: increased


Block/Question (10.9 difficulty score)
A 50-year-old man who is a college professor has had an ...
It must be difficult for you to accept this diagnosis when you feel healthy.

Block/Question (34.8 difficulty score)
A 38-year-old man who lives at sea level flies to a mountain ...
pH: increased;
HCO3-: increased;
Volume: increased


Block/Question (51.1 difficulty score)
Microelectrode injection of antibodies to α-actinin results ...
Area labeled ‘C’

Block/Question (14.8 difficulty score)
A 50-year-old man comes to the physician for follow-up ...
Yes; the patient may wish to consider the money's influence on the physician's recommendation

Block/Question (15.1 difficulty score)
A 38-year-old man with Down syndrome is brought to the ...
Contact adult protective services

Block/Question (26.0 difficulty score)
An 82-year-old woman has been bedridden since surgical repair ...
Carboxylation of precursor proteins

Block/Question (27.4 difficulty score)
A previously healthy 26-year-old woman comes to the physician ...
Acute retroviral infection

Block/Question (43.9 difficulty score)
A 57-year-old woman comes to the physician 2 weeks after ...
Intercostal

Block/Question (41.5 difficulty score)
An 18-year-old man comes to the physician 10 days after ...
C8

Block/Question (33.2 difficulty score)
A 27-year-old woman comes to the physician because of ...
Antiphospholipid antibodies

Block/Question (17.0 difficulty score)
A 50-year-old man with chronic gastritis is diagnosed with a ...
Helicobacter pylori

Block/Question (35.3 difficulty score)
An 85-year-old woman is diagnosed with a fracture of the ...
Morphine is metabolized to active metabolites that accumulate

Block/Question (34.9 difficulty score)
A 42-year-old man comes to the physician because of numbness ...
Sensory neuropathy

Block/Question (43.7 difficulty score)
A 43-year-old man is brought to the emergency department ...
Fibularis (peroneus) brevis

Block/Question (37.3 difficulty score)
A screening test for cancer is developed and applied to 500 ...
Data point labeled ‘A’

Block/Question (38.7 difficulty score)
A study is conducted to assess the prevalence of hypertension ...
Chi-square test

Block/Question (40.5 difficulty score)
A 45-year-old woman comes to the physician for a follow-up ...
25%

Block/Question (31.6 difficulty score)
An 84-year-old woman comes to the physician because of a ...
Downregulation of E-cadherin

Block/Question (28.1 difficulty score)
A 3-month-old girl is brought to the physician by her mother ...
Motor: normal;
Social: delayed;
Verbal and cognitive: delayed


Block/Question (30.6 difficulty score)
A study is conducted to assess the extent of cardiac valvular ...
Type I error: No change;
Type II error: decreased


Block/Question (16.9 difficulty score)
A 45-year-old man with poorly controlled type 2 diabetes ...
Enterococcus faecalis

Block/Question (19.2 difficulty score)
A 12-year-old girl who recently immigrated to the USA from ...
Praziquantel

Block/Question (40.6 difficulty score)
A 45-year-old man with end-stage renal failure is brought to ...
Bicarbonate

Block/Question (72.0 difficulty score)
Which of the following is required for the synthesis of ...
Glutamine

Block/Question (22.1 difficulty score)
A 35-year-old man is admitted to the hospital because he has ...
Absorption of nitrogenous products from the gastrointestinal tract

Block/Question (23.7 difficulty score)
A 25-year-old woman comes to the physician because of a ...
Fasting insulin: increased;
Testosterone: increased;
Luteinizing hormone: increased


Block/Question (39.1 difficulty score)
A 22-year-old man comes to the physician because of ...
47,XXY

Block/Question (25.0 difficulty score)
The risk for hemorrhagic stroke from drug X is investigated ...
Case-control study

Block/Question (54.4 difficulty score)
A 4-year-old boy is brought to the physician by his parents ...
Interstitial inflammation

Block/Question (17.6 difficulty score)
A 62-year-old man comes to the physician's office for ...
Alternative treatments

Block/Question (17.0 difficulty score)
A 35-year-old man with bronchial asthma starts taking ...
Increase in cAMP

Block/Question (48.7 difficulty score)
A 73-year-old man comes to the physician with his wife ...
Blood pressure

Block/Question (32.7 difficulty score)
A 52-year-old man with stable angina pectoris begins ...
Headache

Block/Question (27.6 difficulty score)
A 49-year-old man has had the gradual onset of numbness and ...
Essential thrombocythemia

Block/Question (29.1 difficulty score)
A 56-year-old man develops brief episodes of ventricular ...
CL x Css

Block/Question (19.0 difficulty score)
A 62-year-old man comes to the physician for a follow-up ...
Inorganic phosphorus: increased;
Parathyroid hormone: increased;
Calcitriol: decreased


Block/Question (28.2 difficulty score)
A 53-year-old woman shows evidence of adrenal failure. On CT ...
Autoimmune adrenalitis

Block/Question (20.0 difficulty score)
A 35-year-old man comes to the physician because of an itchy ...
Prescribe permethrin for the patient and his family

Block/Question (49.2 difficulty score)
A 28-year-old man who is seropositive for HIV has numerous ...
Slit-like vascular spaces with plump spindle-shaped stromal cells

Block/Question (10.4 difficulty score)
A 54-year-old woman with hypertension and bilateral renal ...
Vasodilating prostaglandins at the afferent arteriole

Block/Question (35.0 difficulty score)
A 10-year-old boy receives a renal transplant from a living, ...
Lymphocytes infiltrating tubular epithelium

Block/Question (22.3 difficulty score)
A 2-year-old boy is brought to the physician because of fever ...
Bruton agammaglobulinemia

Block/Question (22.2 difficulty score)
A 42-year-old man is brought to the emergency department ...
Dopaminergic neurons in the substantia nigra

Block/Question (17.9 difficulty score)
A 56-year-old woman is brought to the emergency department by ...
Herpes encephalitis

Block/Question (44.2 difficulty score)
A 2-day-old full-term female newborn suddenly develops ...
Superior mesenteric

Block/Question (29.3 difficulty score)
Thirty minutes after taking 2 aspirin tablets for a tension ...
Acetaminophen

Block/Question (24.1 difficulty score)
A 60-year-old man comes to the physician because of ...
Alveolar macrophage

Block/Question (39.6 difficulty score)
A 24-year-old man who is comatose is admitted to the hospital ...
25 mL/cm H2O

Block/Question (50.2 difficulty score)
A new virus has been isolated that causes encephalitis. The ...
Single-stranded positive-sense

Block/Question (15.3 difficulty score)
A population of vegetarians is surveyed to investigate the ...
t-Test

Block/Question (25.3 difficulty score)
A 27-year-old man comes to the physician for a routine ...
Ask the patient to identify the pros and cons of smoking cessation

Block/Question (18.4 difficulty score)
A 6-year-old boy who recently emigrated from Russia is ...
Vitamin E

Block/Question (37.1 difficulty score)
A 5-year-old boy is brought to the physician because of a ...
Interruption of erythrocyte production

Block/Question (42.7 difficulty score)
An 81-year-old man comes to the physician for ongoing ...
Atherosclerosis

Block/Question (17.9 difficulty score)
A 26-year-old woman comes to the physician 5 weeks after the ...
Sertraline

Block/Question (13.3 difficulty score)
A 73-year-old woman dies 7 years after the onset of ...
Hydrocephalus ex vacuo

Block/Question (14.6 difficulty score)
A 36-year-old woman comes to the physician because of a ...
Cytosol with translocation into the nucleus

Block/Question (40.4 difficulty score)
In patients with adenosine deaminase deficiency, there is a ...
Ribonucleotide reductase

Block/Question (52.7 difficulty score)
A 24-year-old woman, gravida 1, para 1, comes to the ...
Release of stored thyroid hormone from a thyroid gland infiltrated by lymphocytes

Block/Question (25.9 difficulty score)
A 4-month-old boy is brought to the office by his parents ...
Maxillary and medial nasal prominences

Block/Question (14.3 difficulty score)
A 62-year-old man with dyslipidemia is brought to the ...
Gemfibrozil

Block/Question (34.7 difficulty score)
A 10-year-old girl has a slightly painful 2-mm subcutaneous ...
Granuloma

Block/Question (35.0 difficulty score)
A 76-year-old man with a 1-month history of a pulsatile ...
Anomalous origins of multiple renal arteries to each kidney

Block/Question (34.3 difficulty score)
During a study of symptomatic proximal deep venous ...
Open-label clinical trial

Block/Question (15.4 difficulty score)
A previously healthy 45-year-old woman has had fever, ...
Thrombotic thrombocytopenic purpura

Block/Question (21.2 difficulty score)
A 37-year-old man comes to the physician for a follow-up ...
Hyperplastic arteriolosclerosis

Block/Question (17.4 difficulty score)
A 57-year-old woman comes to the office because of a 5-week ...
Autoimmune downregulation of Ca2+ channels of the presynaptic terminal

Block/Question (23.3 difficulty score)
A 39-year-old woman with rheumatoid arthritis comes to the ...
Tumor necrosis factor-α

Block/Question (22.7 difficulty score)
A healthy 25-year-old man eats a meal consisting of 60% ...
Fusion of an intracellular vesicle with the plasma membrane

Block/Question (32.6 difficulty score)
A 60-year-old woman comes to the physician because of a ...
Meningioma

Block/Question (42.0 difficulty score)
A 78-year-old man comes to the physician because of a 3-month ...
Metastatic carcinoma

Block/Question (36.7 difficulty score)
A 48-year-old man comes to the emergency department because ...
Splenic vein

Block/Question (23.2 difficulty score)
A 45-year-old man who is HIV positive comes to the physician ...
Disruption of the pathogen cell membrane

Block/Question (35.6 difficulty score)
A 27-year-old man who is a construction worker is brought to ...
Splenic flexure

Block/Question (28.3 difficulty score)
A 65-year-old man comes to the emergency department because ...
Crackles

Block/Question (34.9 difficulty score)
A case-control study is conducted to assess the relationship ...
Cannot be determined from the data given

Block/Question (27.7 difficulty score)
A 38-year-old single woman with a history of chronic ...
Displacement

Block/Question (15.8 difficulty score)
A 17-year-old boy comes to the physician because of a 1-week ...
B lymphocyte

Block/Question (38.2 difficulty score)
Nicotinic acid acts at which of the following labeled sites ...
Pathway labeled ‘C’

Block/Question (21.1 difficulty score)
A 38-year-old man is admitted to the hospital after ...
Acute-phase response

Block/Question (35.9 difficulty score)
A 53-year-old woman with a long history of fibromuscular ...
Tubular atrophy

Block/Question (20.8 difficulty score)
Patients with mucolipidosis II (I-cell disease) lack the ...
Secreted from the cells

Block/Question (34.8 difficulty score)
A 5-year-old boy is brought to the physician because of pain ...
Retinal cells

Block/Question (17.0 difficulty score)
A 5-year-old boy with mental retardation is grossly obese and ...
Maternal origin of both chromosomes 15

Block/Question (26.0 difficulty score)
A 65-year-old woman with a 20-year history of osteoarthritis ...
L-3 to 4

Block/Question (11.6 difficulty score)
A 31-year-old man comes to the physician because of concerns ...
Dihydrotestosterone

Block/Question (24.1 difficulty score)
A 44-year-old man comes to the physician because of fever and ...
Tricuspid insufficiency

Block/Question (35.7 difficulty score)
A 10-year-old boy has bruised easily since swallowing some of ...
Prolonged prothrombin time

Block/Question (28.3 difficulty score)
An 1814-g (4-lb) male newborn is delivered in the hospital at ...
Endodermal cells

Block/Question (53.7 difficulty score)
A 39-year-old woman comes to the physician because of ...
Hemoglobin

Block/Question (44.4 difficulty score)
A 56-year-old woman comes to the physician for a follow-up ...
Maintenance of basement membrane integrity

Block/Question (32.7 difficulty score)
An 8-year-old boy is brought to the physician by his parents ...
Calorie consumption that exceeds energy expenditure

Block/Question (19.0 difficulty score)
A 52-year-old man with metastatic oat cell carcinoma begins ...
Ensure that the patient receives enough medication to control his pain

Block/Question (37.9 difficulty score)
A 31-year-old woman in the second trimester of pregnancy is ...
Hematopoietic stem cells

NBME 21

Block/Question (42.9 difficulty score)
A 24-year-old woman with sickle cell disease comes to the ...
Serum parvovirus B19 IgM antibody test

Block/Question (52.7 difficulty score)
A 6-month-old girl is brought to the physician because her ...
GM2

Block/Question (53.3 difficulty score)
An investigator is studying the efficacy of distinct vaccine ...
Flagellin

Block/Question (23.8 difficulty score)
A 67-year-old man comes to the emergency department because ...
Translation

Block/Question (44.7 difficulty score)
A 45-year-old woman is brought to the emergency department 45 ...
Absorption atelectasis

Block/Question (54.8 difficulty score)
A normal-appearing 17-year-old girl has never had a menstrual ...
Androgen insensitivity syndrome

Block/Question (20.8 difficulty score)
A 30-year-old primigravid woman at 22 weeks' gestation comes ...
Listeria monocytogenes

Block/Question (23.6 difficulty score)
A 52-year-old woman is admitted to the hospital because of ...
Speak with the two gynecologists to attempt to coordinate care

Block/Question (13.0 difficulty score)
A 53-year-old woman who underwent an operation for breast ...
Breast: antagonist; Uterus: partial agonist

Block/Question (24.1 difficulty score)
A 34-year-old woman is brought to the emergency department 30 ...
Primary metabolic acidosis with increased anion gap

Block/Question (33.4 difficulty score)
A 27-year-old primigravid woman at 34 weeks' gestation is ...
Schistocytes

Block/Question (37.5 difficulty score)
A 25-year-old nulligravid woman comes to the physician ...
Endometrial hyperplasia

Block/Question (35.1 difficulty score)
A 25-year-old man develops shortness of breath after moving ...
Decreased alveolar Po2

Block/Question (17.0 difficulty score)
A 21-year-old man is brought to the emergency department 45 ...
Streptococcus pneumoniae

Block/Question (39.9 difficulty score)
A 35-year-old man comes to the physician because of a 1-day ...
Increased vascular permeability

Block/Question (52.8 difficulty score)
A 43-year-old man comes to the physician for a follow-up ...
Aortic

Block/Question (70.2 difficulty score)
A 7-year-old girl is brought to a clinic in a developing ...
Methionine

Block/Question (20.8 difficulty score)
A 61-year-old woman is brought to the physician by her ...
Donepezil

Block/Question (39.5 difficulty score)
A 22-year-old man has had frequent episodes of cutaneous ...
C1 esterase inhibitor (binds activated C1r, C1s)

Block/Question (25.8 difficulty score)
A 10-year-old girl develops fever, malaise, and loss of ...
Retrograde transport through nerves

Block/Question (22.0 difficulty score)
A 40-year-old man with type 2 diabetes mellitus comes to the ...
Stimulation of the peroxisome proliferator-activated receptor γ

Block/Question (33.4 difficulty score)
A 36-year-old man with AIDS elects to participate in a ...
Chemokine

Block/Question (41.3 difficulty score)
A 59-year-old man comes to the physician because of a 3-month ...
Foci of keratinization

Block/Question (51.7 difficulty score)
A 23-year-old man drinks alcohol heavily on a weekend. Which ...
Fatty change

Block/Question (39.7 difficulty score)
A 28-year-old man is brought to the emergency department 30 ...
Dissecting aneurysm

Block/Question (32.4 difficulty score)
A 62-year-old man who is a farmer comes to the physician ...
Actinic keratosis

Block/Question (24.0 difficulty score)
A 60-year-old man is brought to the emergency department ...
Urethral disruption

Block/Question (57.0 difficulty score)
A 47-year-old man is brought to the emergency department by ...
Mixed venous oxygen tension

Block/Question (14.1 difficulty score)
A 34-year-old man comes to the physician because of a 2-week ...
Cluster headache

Block/Question (39.9 difficulty score)
A newborn has female external genitalia and a 46,XY ...
Dihydrotestosterone

Block/Question (47.1 difficulty score)
A 30-year-old woman comes to the office for a follow-up ...
Linoleic acid

Block/Question (53.3 difficulty score)
A 50-year-old man has had progressive dyspnea on exertion ...
Usual interstitial pneumonitis

Block/Question (21.6 difficulty score)
A 30-year-old man comes to the physician because of a ...
Varicella-zoster virus infection

Block/Question (51.4 difficulty score)
A 30-year-old man develops urinary incontinence 2 weeks after ...
Pelvic nerves

Block/Question (28.7 difficulty score)
A 7-year-old boy is brought to the physician by his mother ...
Increased blood lead

Block/Question (55.1 difficulty score)
A 51-year-old woman comes to the physician because of a ...
Area labeled 'B' (Parietal cell)

Block/Question (18.7 difficulty score)
A 35-year-old man with diabetic ketoacidosis has a decrease ...
Serum potassium concentration

Block/Question (20.6 difficulty score)
A 47-year-old woman with aplastic anemia is being treated for ...
Amphotericin B

Block/Question (31.1 difficulty score)
A 33-year-old woman comes to the physician because of fever, ...
Genital herpes

Block/Question (29.4 difficulty score)
A physician prescribes a recently marketed drug for 20 ...
Phase 4

Block/Question (27.3 difficulty score)
A 35-year-old woman comes to the physician because of a 2-day ...
Uroporphyrinogen decarboxylase

Block/Question (35.5 difficulty score)
A 36-year-old woman undergoes a total hysterectomy and ...
Hyperplasia

Block/Question (33.4 difficulty score)
A 52-year-old man is brought to the emergency department 30 ...
Histamine

Block/Question (16.3 difficulty score)
A test has been developed to screen for human papillomavirus ...
Predictive value of a positive test

Block/Question (38.9 difficulty score)
An 18-year-old man comes to the physician because of a 2-week ...
Pyruvate kinase

Block/Question (26.7 difficulty score)
A 66-year-old man is brought to the emergency department ...
Lipopolysaccharide stimulation of toll-like receptor

Block/Question (50.6 difficulty score)
A 26-year-old woman (III-2) comes to the physician for ...
50% in females but near 0 in males

Block/Question (29.7 difficulty score)
A 44-year-old man is admitted to the hospital because of ...
Increasing cGMP

Block/Question (33.2 difficulty score)
An 80-year-old woman comes to the emergency department ...
Hydrochlorothiazide

Block/Question (42.3 difficulty score)
A photograph is shown of a myelin-stained cross section of a ...
Loss of sensation to vibration over both feet

Block/Question (15.1 difficulty score)
A 27-year-old man comes to the physician for an examination ...
Schizoid

Block/Question (37.5 difficulty score)
A 4-year-old girl is conscious but unable to breathe ...
Pseudocholinesterase deficiency

Block/Question (47.4 difficulty score)
A 17-year-old boy returns to the locker room after football ...
Apocrine

Block/Question (27.9 difficulty score)
An 18-year-old woman comes to the office because of a 2-week ...
Extensor carpi radialis brevis

Block/Question (64.3 difficulty score)
A 2-week-old male newborn has a patent ductus arteriosus. ...
Higher than normal left ventricular cardiac output

Block/Question (49.5 difficulty score)
A 38-year-old woman comes to the physician because of a ...
Serum calcium concentration

Block/Question (28.3 difficulty score)
A 50-year-old man with rheumatoid arthritis comes to the ...
Anemia of chronic disease

Block/Question (48.7 difficulty score)
A 55-year-old man is diagnosed with renal artery stenosis. ...
Cortex

Block/Question (25.4 difficulty score)
A 40-year-old man is brought to the emergency department 45 ...
Metabolic acidosis and respiratory acidosis

Block/Question (28.4 difficulty score)
A 42-year-old woman comes to the physician because of a ...
Rosacea

Block/Question (33.1 difficulty score)
A 22-year-old woman, gravida 1, para 1, is brought to the ...
Internal iliac

Block/Question (62.6 difficulty score)
A 66-year-old woman comes to the physician because of fever, ...
Diverticulitis

Block/Question (37.1 difficulty score)
A 53-year-old woman with gastroesophageal reflux disease ...
Omeprazole

Block/Question (70.2 difficulty score)
A 30-year-old woman comes to the office because she is ...
Abnormal brain development

Block/Question (53.6 difficulty score)
A 48-year-old man is brought to the emergency department ...
Splenic and left renal

Block/Question (49.4 difficulty score)
A 34-year-old woman comes to the physician because of a ...
Atrioventricular bundle

Block/Question (26.4 difficulty score)
Scientists have identified the flawed gene that causes about ...
Mismatch repair

Block/Question (33.6 difficulty score)
A 34-year-old woman comes to the physician because she has ...
“I’m concerned about how bad you’ve been feeling lately. Have you had any thoughts about death or wanting to be dead?”

Block/Question (39.4 difficulty score)
A 3-year-old boy who recently immigrated to the USA is ...
Increased proportions of osteoid

Block/Question (43.7 difficulty score)
A 14-year-old girl is brought to the physician by her mother ...
Trichotillomania

Block/Question (50.1 difficulty score)
A 35-year-old woman undergoes flexible nasopharyngoscopy ...
Superior to the superior concha

Block/Question (32.6 difficulty score)
A 33-year-old woman, gravida 4, para 4, is admitted to the ...
Transfusion-related acute lung injury

Block/Question (28.0 difficulty score)
A 4-year-old boy with chronic granulomatous disease is ...
Macrophages producing interleukin-1 (IL-1)

Block/Question (55.1 difficulty score)
A 65-year-old man dies in a motor vehicle collision. A ...
Squamous cell carcinoma

Block/Question (18.8 difficulty score)
A 54-year-old man comes to the physician for a routine health ...
Area labeled 'F' (Efferent arteriole)

Block/Question (39.8 difficulty score)
A healthy 32-year-old woman at 35 weeks' gestation is ...
Birth canal reflex

Block/Question (12.9 difficulty score)
A 47-year-old woman with psoriasis comes to the physician for ...
“Most people find it difficult to stick to a routine. How did you do?”

Block/Question (14.4 difficulty score)
A 64-year-old woman with type 2 diabetes mellitus and ...
Gemfibrozil

Block/Question (56.7 difficulty score)
A healthy 25-year-old man is participating in a study of ...
Alanine

Block/Question (25.6 difficulty score)
A 44-year-old man comes to the physician because of ...
Leukotriene C4: increased;
Arachidonic acid: increased;
Prostaglandin H2: decreased;
Prostaglandin E2: decreased


Block/Question (48.7 difficulty score)
A 37-year-old man is brought to the emergency department 45 ...
Intercostal

Block/Question (20.7 difficulty score)
A 17-year-old boy has the acute onset of lethargy, sore ...
Lymphocytes

Block/Question (53.0 difficulty score)
A 68-year-old man comes to the physician because of a 1-month ...
Libido: normal; Nocturnal erections: normal

Block/Question (44.6 difficulty score)
A 28-year-old man is brought to the emergency department ...
Inferior rectus and inferior oblique

Block/Question (60.7 difficulty score)
A 4-month-old female infant is brought to the emergency ...
Hyponatremia

Block/Question (15.5 difficulty score)
An investigator is conducting a study of antiretroviral ...
Enfuvirtide

Block/Question (25.6 difficulty score)
A 17-year-old boy is evaluated for constitutional delay in ...
Craniopharyngioma

Block/Question (13.6 difficulty score)
A 63-year-old man with bladder cancer starts treatment with ...
Tubulin polymerization stabilization

Block/Question (44.0 difficulty score)
A 64-year-old man with bronchospastic pulmonary disease ...
Enhanced action of the agonist at β-adrenergic receptors

Block/Question (28.9 difficulty score)
Acetaminophen and nonsteroidal antiinflammatory agents reduce ...
Prostaglandin E2

Block/Question (28.6 difficulty score)
A 75-year-old woman has the sudden onset of Horner syndrome ...
Posterior inferior cerebellar

Block/Question (17.7 difficulty score)
A 26-year-old man with HIV infection comes to the physician ...
Penicillin

Block/Question (32.1 difficulty score)
A 78-year-old woman is brought to the emergency department by ...
Embolectomy

Block/Question (23.1 difficulty score)
A 75-year-old man has the sudden onset of partial loss of ...
Parietal lobe, left

Block/Question (30.2 difficulty score)
A 3-year-old boy is brought to the emergency department ...
Synthesis of factor X (Stuart factor)

Block/Question (33.7 difficulty score)
An 8-year-old girl is brought to the physician for a ...
“Your daughter’s development is normal.”

Block/Question (37.2 difficulty score)
A 55-year-old woman comes to the physician because of a ...
Increased parathyroid hormone

Block/Question (34.3 difficulty score)
A 75-year-old man has fever, back pain, and pain on ...
Enterococcus faecalis

Block/Question (23.4 difficulty score)
A 6-year-old girl is brought to the physician by her mother ...
Poxvirus

Block/Question (46.7 difficulty score)
A 65-year-old woman comes to the emergency department because ...
Lung and common carotid artery

Block/Question (14.7 difficulty score)
A 30-year-old woman develops dimness of vision
Ethambutol

Block/Question (31.3 difficulty score)
A 40-year-old man with interstitial pulmonary fibrosis has a ...
Increased radial traction on airways

Block/Question (13.6 difficulty score)
A 55-year-old African American man with hypertension is asked ...
Tell the patient that he can change his mind about participating

Block/Question (41.4 difficulty score)
A clinical trial is conducted to compare the efficacy of a ...
Surgical procedure group: 400; Medical management group: 400

Block/Question (40.3 difficulty score)
A 70-year-old woman is found to have persistent fever despite ...
Candida albicans

Block/Question (34.2 difficulty score)
A 40-year-old African American woman comes to the physician ...
1,25-Dihydroxycholecalciferol

Block/Question (45.8 difficulty score)
A 65-year-old man comes to the physician because of a 1-month ...
DNA fragmentation

Block/Question (40.3 difficulty score)
A 55-year-old woman is brought to the emergency department by ...
Mammillary bodies

Block/Question (32.5 difficulty score)
A 75-year-old woman is brought to the emergency department ...
Shrunken eosinophilic (red) neurons

Block/Question (20.6 difficulty score)
A 30-year-old man has had intermittent severe lower abdominal ...
Cysteine

Block/Question (58.7 difficulty score)
A 50-year-old man is found dead in bed at home. His family ...
Arrhythmia

Block/Question (37.6 difficulty score)
A 55-year-old man with hypertension comes to the physician ...
Left renal artery atherosclerosis

Block/Question (32.3 difficulty score)
A 40-year-old woman comes to the physician for an initial ...
Antagonizes VLDL-cholesterol secretion

Block/Question (17.3 difficulty score)
A 35-year-old man is brought to the emergency department ...
Activation of adenylyl cyclase

Block/Question (38.8 difficulty score)
A 47-year-old man has jaundice. Laboratory findings include ...
Obstruction of the bile duct

Block/Question (54.2 difficulty score)
A 16-year-old boy is brought to the physician because of a ...
Exercise-induced asthma

Block/Question (35.5 difficulty score)
A 66-year-old woman with pancreatic cancer comes to the ...
Short gastric

Block/Question (31.3 difficulty score)
An 83-year-old man comes to the physician because of a 3-day ...
Bullous pemphigoid antigen

Block/Question (39.4 difficulty score)
A 25-year-old woman develops increasing shortness of breath ...
Four-chamber dilation

Block/Question (46.1 difficulty score)
A 68-year-old woman has had a fever and shortness of breath ...
Reactive granulocytosis

Block/Question (43.3 difficulty score)
A screening program is instituted for detection of vaginal ...
10%

Block/Question (33.3 difficulty score)
A 9-year-old boy has mild mental retardation and a 4-year ...
Rhabdomyoma

Block/Question (34.7 difficulty score)
A 43-year-old woman dies after a 10-year illness ...
Area labeled ‘C’ (Caudate nucleus)

Block/Question (44.8 difficulty score)
Diastolic blood pressures are obtained in two groups of 100 ...
Median of group Y: higher; Mode of group Y: higher

Block/Question (40.4 difficulty score)
A 32-year-old woman comes to the physician because her sister ...
Dysplastic nevi

Block/Question (39.3 difficulty score)
A 19-year-old woman comes to the office because of a 1-month ...
Descending colon

Block/Question (35.8 difficulty score)
A 55-year-old woman with a benign nodule in the left lobe of ...
External carotid

Block/Question (62.4 difficulty score)
A 1-year-old girl is admitted to the hospital because of a ...
Disruption of the secondary structure of collagen molecules

Block/Question (25.7 difficulty score)
A 34-year-old man is evaluated after becoming light-headed ...
Number of impulses from carotid baroreceptor: decreased;
Sympathetic efferent activity: increased;
Parasympathetic efferent activity: decreased


Block/Question (41.0 difficulty score)
A 41-year-old man comes to the physician because of a 6-week ...
Abduction of the upper extremity

Block/Question (44.1 difficulty score)
A 28-year-old woman at 18 weeks' gestation has palpitations. ...
Free T4

Block/Question (22.1 difficulty score)
A 72-year-old man comes to the physician because of a 2-week ...
Bleomycin

Block/Question (53.1 difficulty score)
Left radial arterial and venous blood samples are drawn from ...
HCO3 transported in the plasma

Block/Question (35.7 difficulty score)
A 39-year-old woman with rheumatoid arthritis develops ...
Membranous glomerulonephritis

Block/Question (50.9 difficulty score)
A 63-year-old woman comes to the physician because of a 5-day ...
Increased resting cardiac output

Block/Question (61.3 difficulty score)
Which of the following best explains why the use of an ...
Myeloma cells do not have membrane-bound surface immunoglobulin

Block/Question (58.5 difficulty score)
A 5-year-old boy who has homocystinuria improves with ...
The line on the graph labeled ‘B’

Block/Question (31.4 difficulty score)
A 28-year-old man develops a temperature of 39.9°C (103.8°F) ...
Granulocyte colony-stimulating factor

Block/Question (23.8 difficulty score)
A 74-year-old woman with mild dementia is admitted to the ...
Inability to understand the severity and prognosis of her medical condition

Block/Question (34.5 difficulty score)
A 65-year-old woman undergoes surgical repair of an aneurysm ...
Area labeled ‘A’ (Cranial nerve 3)

Block/Question (32.7 difficulty score)
A 75-year-old woman comes to the physician's office because ...
Major depressive disorder

Block/Question (30.9 difficulty score)
A 27-year-old primigravid woman at 39 weeks' gestation is ...
Shoulder dystocia

Block/Question (19.4 difficulty score)
An undernourished 70-year-old man has fever, night sweats, ...
Interferon-γ

Block/Question (37.1 difficulty score)
A 23-year-old woman develops persistent sneezing each year in ...
Stabilization of mast cell membranes

Block/Question (54.6 difficulty score)
A 28-year-old man comes to the physician for evaluation of ...
Fructose

Block/Question (14.9 difficulty score)
A 38-year-old woman comes to the physician because of a ...
Patent foramen ovale

Block/Question (23.4 difficulty score)
A 48-year-old man comes to the physician because of ...
Increased intestinal iron absorption

Block/Question (26.2 difficulty score)
A 29-year-old woman comes to the physician because of a ...
Baclofen

Block/Question (46.6 difficulty score)
The gene that codes for a protein normally found in the ...
Deletion of a hydrophobic amino acid sequence from the N terminus

Block/Question (52.9 difficulty score)
A 32-year-old woman comes to the emergency department because ...
Arthropod vector

Block/Question (41.1 difficulty score)
A 50-year-old woman has azotemia. Renal ultrasonography shows ...
Uterine cervix

Block/Question (39.2 difficulty score)
A 23-year-old woman comes to the student health center ...
Obliterative endarteritis with lymphocytes and plasma cells

Block/Question (21.9 difficulty score)
A study was performed that evaluated the relationship between ...
Odds ratio

Block/Question (56.6 difficulty score)
The FOXO transcription factor responds to insulin signaling ...
Nuclear/cytoplasmic shuttling: yes;
Serine phosphorylation: yes
Ubiquitin-mediated proteolysis: no


Block/Question (45.7 difficulty score)
An 11-year-old boy has had persistent pain in his right knee ...
Lung

Block/Question (35.8 difficulty score)
A 55-year-old man comes to the physician because of a 2-month ...
Cortisol

Block/Question (40.6 difficulty score)
A 14-year-old boy is brought to the physician by his mother ...
Inhaled glue

Block/Question (43.5 difficulty score)
A 70-year-old woman has had recurrent pneumonia, fatigue, and ...
Euthyroid sick syndrome

Block/Question (35.4 difficulty score)
A 60-year-old woman with psoriasis comes to the physician ...
Porphyria cutanea tarda

Block/Question (41.1 difficulty score)
A 64-year-old man is evaluated for cough, dyspnea, and chest ...
Hyponatremia

Block/Question (32.8 difficulty score)
A study is conducted on patients with asthma to compare a new ...
If the treatment really changes the mean asthma score by 0.4, there is an 80% chance that a study of this size will find a p-value < 0.05

Block/Question (32.3 difficulty score)
A 24-year-old man with a history of drug abuse has nausea, ...
Heroin

Block/Question (45.5 difficulty score)
A 4-month-old boy is diagnosed with a rare autosomal ...
Dilated rough endoplasmic reticulum

Block/Question (47.9 difficulty score)
A 25-year-old woman has a 3-week history of bleeding gums ...
Autoantibodies against platelet glycoproteins

Block/Question (50.7 difficulty score)
A 5-year-old boy is brought to the physician for a well-child ...
Lack of choroidal pigment deposition in the macula

Block/Question (18.2 difficulty score)
A 40-year-old woman who had pneumonia due to Streptococcus ...
Surfactant

Block/Question (26.9 difficulty score)
A 48-year old man is referred for evaluation of possible ...
Increase in width

Block/Question (11.1 difficulty score)
A previously healthy 4-week-old male newborn is brought to ...
Pyloric stenosis

Block/Question (30.8 difficulty score)
A 45-year-old woman comes to the emergency department because ...
Hepatopancreatic ampulla

Block/Question (51.3 difficulty score)
A 7-month-old boy is brought to the physician 2 days after ...
46,XY

Block/Question (10.4 difficulty score)
A 47-year-old man is treated with colchicine for acute gouty ...
Tubulin polymerization

Block/Question (40.6 difficulty score)
A 57-year-old woman is brought to the emergency department ...
Ninth

Block/Question (52.5 difficulty score)
An investigator is studying the regulation of pulmonary ...
Intravenous infusion of 0.9% saline for 5 minutes

Block/Question (32.0 difficulty score)
A 56-year-old man undergoes a renal transplant. Five minutes ...
IgG plus complement

Block/Question (56.2 difficulty score)
An 80-year-old woman cannot concentrate her urine above 450 ...
2.0

Block/Question (22.9 difficulty score)
The immunosuppressive agent cyclosporin A (CsA) is a potent ...
Interleukin-2 (IL-2) gene transcription

Block/Question (31.9 difficulty score)
A 65-year-old woman is being treated in the hospital for ...
“The two of you seem to have a very important relationship. Of course you may stay together.”

Block/Question (25.7 difficulty score)
A 56-year-old man undergoes surgical resection of the ...
Release of cholecystokinin

Block/Question (28.9 difficulty score)
A 22-year-old man comes to the physician because of a 2-month ...
Formation of destructive free radicals

Block/Question (32.5 difficulty score)
A 5-year-old boy is admitted to the hospital because of ...
ApoC-II

Block/Question (29.3 difficulty score)
A 48-year-old woman comes to the physician because of a ...
Paracrine stimulation of osteoclasts by osteoblasts

Block/Question (13.6 difficulty score)
A 19-year-old college student says he hears voices." He was ...
Risperidone

Block/Question (44.4 difficulty score)
A female newborn delivered at 26 weeks' gestation is found to ...
Retina

Block/Question (43.4 difficulty score)
A healthy 8-year-old boy is brought to the physician by his ...
Stimulation of the release of biogenic amine neurotransmitters

Block/Question (22.9 difficulty score)
A 50-year-old woman is admitted to the hospital because of a ...
Didanosine (ddI)

Block/Question (50.8 difficulty score)
A 45-year-old man comes to the physician because of ...
Chondrosarcoma

Block/Question (41.9 difficulty score)
A 66-year-old right-handed woman develops the acute onset of ...
Area labeled 'B' (Internal capsule)

Block/Question (27.6 difficulty score)
A 62-year-old woman is brought to the physician by her ...
Instruct the patient to keep notes and lists to help her memory

Block/Question (41.8 difficulty score)
A 46-year-old man comes to the physician because of a 2-month ...
1/15

Block/Question (45.1 difficulty score)
A study is conducted to assess the normal mean serum urea ...
500 Men from a list of patients scheduled to be examined by a urologist

Block/Question (14.5 difficulty score)
A 66-year-old man with stage IV colon cancer comes to the ...
Loperamide

Block/Question (19.2 difficulty score)
A 20-year-old primigravid woman at 12 weeks' gestation comes ...
Multifactorial

Block/Question (22.2 difficulty score)
A 4-year-old boy falls and lacerates his lower leg to the ...
Formation of fibrin clot

Block/Question (34.0 difficulty score)
A 28-year-old woman with chronic renal failure (creatinine ...
Furosemide

Block/Question (58.5 difficulty score)
During an experiment, an investigator observes that glutamate ...
NMDA receptors are blocked by Mg2+ at the resting membrane potential

Block/Question (40.2 difficulty score)
A 14-year-old girl is brought to the physician for a ...
TP53

Block/Question (21.4 difficulty score)
While lifting weights, a 24-year-old man develops a painful ...
Strangulation

Block/Question (33.1 difficulty score)
A 75-year-old man with dementia, Alzheimer type, is brought ...
Encourage the family to come to a consensus based on their perception of the patient's wishes

Block/Question (36.6 difficulty score)
A 76-year-old man comes to the physician because of a 2-week ...
Left thalamus

Block/Question (17.9 difficulty score)
A 19-year-old woman is brought to the emergency department 30 ...
Scaphoid

NBME 20

Block/Question (50.6 difficulty score)
A 37-year-old nurse is accidentally stuck with a needle used ...
Inhibits reverse transcriptase

Block/Question (36.7 difficulty score)
A mother who has toxoplasmosis gives birth to an asymptomatic ...
Antitoxoplasma IgM antibody concentrations

Block/Question (23.0 difficulty score)
A 48-year-old man comes to the physician for a routine ...
Upregulation of the LDL receptors

Block/Question (38.3 difficulty score)
A 50-year-old man is brought to the emergency department by ...
Formic acid

Block/Question (22.5 difficulty score)
A 24-year-old African American man comes to the physician ...
Pseudofolliculitis barbae

Block/Question (42.1 difficulty score)
A 16-year-old student has uncontrollable sleepiness, falling ...
Direct transition from wakefulness to REM sleep

Block/Question (32.5 difficulty score)
A 5-year-old girl with AIDS develops a progressive ...
Thymidine kinase

Block/Question (27.0 difficulty score)
A 10-year-old girl is brought to the physician by her mother ...
Breast bud development

Block/Question (25.6 difficulty score)
A 50-year-old man is brought to the physician by his wife ...
Pick disease

Block/Question (38.9 difficulty score)
A 77-year-old woman has been having difficulty fastening ...
C7-T1 foraminal stenosis

Block/Question (32.8 difficulty score)
The sequence surrounding the first two exons of the human ...
Disruption of normal splicing by creation of a new 3′ splice site

Block/Question (71.4 difficulty score)
A 72-year-old woman with dysphagia is undergoing surgical ...
Right kidney

Block/Question (34.3 difficulty score)
A 6-week-old girl is brought to the physician by her mother ...
Immature lower esophageal sphincter

Block/Question (37.5 difficulty score)
A 28-year-old man who is a migrant worker comes to the clinic ...
Psoas major

Block/Question (42.0 difficulty score)
A 30-year-old man who completed a successful course of ...
Adjustment disorder with anxiety

Block/Question (47.8 difficulty score)
A 30-year-old woman with multiple sclerosis comes to the ...
Pons

Block/Question (74.1 difficulty score)
A 50-year-old woman comes to the physician because of a ...
Drug effect

Block/Question (37.0 difficulty score)
A 36-year-old man comes to the physician because he has not ...
Urine output: increased; Urine potassium: increased

Block/Question (35.2 difficulty score)
A 60-year-old man comes to the physician because of a 6-week ...
Urine Na+: increased; Serum osmolality: decreased

Block/Question (36.7 difficulty score)
An 8-year-old boy is evaluated for ventricular systolic ...
Coarctation of the aorta

Block/Question (31.6 difficulty score)
A 75-year-old woman comes to the physician because of a ...
Multinucleated giant cells and neutrophil infiltrates

Block/Question (22.5 difficulty score)
A 38-year-old woman comes to the physician because of a 3-day ...
Vagus

Block/Question (39.9 difficulty score)
A 34-year-old man who is HIV positive is brought to the ...
CD4+ T lymphocytes

Block/Question (47.6 difficulty score)
A 50-year-old man comes to the physician because of a ...
Omeprazole

Block/Question (29.4 difficulty score)
A 25-year-old primigravid woman at 42 weeks’ gestation is ...
Phosphoinositide hydrolysis

Block/Question (26.2 difficulty score)
Serum cholesterol concentrations are measured as part of a ...
16%

Block/Question (21.1 difficulty score)
A 53-year-old woman comes to the physician because of a ...
Schistosoma mansoni

Block/Question (13.6 difficulty score)
A previously healthy 16-year-old girl comes to the physician ...
Trichomonas vaginalis

Block/Question (47.0 difficulty score)
During an experiment, an investigator isolates an abnormal ...
Lysine

Block/Question (30.3 difficulty score)
A 33-year-old woman comes to the emergency department 1 hour ...
Lunate

Block/Question (39.8 difficulty score)
A 66-year-old man has had fatigue, shortness of breath, and ...
Focal pulmonary fibrosis

Block/Question (39.6 difficulty score)
A 56-year-old woman is brought to the emergency department ...
Placement of the central line via the left internal jugular vein

Block/Question (44.0 difficulty score)
A 17-year-old girl comes to the emergency department because ...
Mitochondrial

Block/Question (41.9 difficulty score)
A strain of Escherichia coli produces a temperature-sensitive ...
Missense

Block/Question (63.5 difficulty score)
A 70-year-old man dies of coronary artery disease. He had a ...
Spastic hemiparesis on the right

Block/Question (20.9 difficulty score)
A 56-year-old man is admitted to the hospital after an ...
Rhabdomyolysis

Block/Question (56.8 difficulty score)
A 1-month-old male newborn is brought to the emergency ...
Na+: 132; K+: 3.2; Cl: 90; HCO3: 37

Block/Question (25.6 difficulty score)
A 9-year-old girl is brought to the physician because of poor ...
Diverticulum of the roof of the embryonic oral cavity

Block/Question (29.6 difficulty score)
A 3-month-old boy is brought to the office by his mother ...
Lateral to the inferior epigastric artery and superior to the inguinal ligament

Block/Question (42.2 difficulty score)
Monoclonality of neoplastic cells in endometrial carcinoma ...
X chromosome-linked isoenzymes

Block/Question (27.0 difficulty score)
A 45-year-old man has fever, chills, dysuria, and a tender, ...
Escherichia coli

Block/Question (32.8 difficulty score)
A 60-year-old man has two-pillow orthopnea, severe dyspnea, ...
Jugular venous pressure of 12 mm Hg

Block/Question (38.8 difficulty score)
A randomized clinical trial is conducted to compare wound ...
Neither procedure is superior

Block/Question (28.5 difficulty score)
A 35-year-old woman with newly diagnosed hypertension comes ...
MR angiography of the renal arteries

Block/Question (18.8 difficulty score)
A 2-year-old boy is brought to the physician because of ...
Amino Acids: decreased; Glucose: decreased; Phosphate: decreased; HCO3–: decreased

Block/Question (34.7 difficulty score)
A 55-year-old woman comes to the physician for a follow-up ...
Cholecalciferol

Block/Question (24.0 difficulty score)
A 60-year-old woman with type 2 diabetes mellitus is brought ...
Rupture of a papillary muscle

Block/Question (28.4 difficulty score)
An otherwise healthy 4-month-old girl is brought to the ...
Spontaneous involution

Block/Question (56.0 difficulty score)
A 56-year-old man comes to the physician because of a 6-month ...
Fibromuscular hyperplasia of arterioles

Block/Question (12.3 difficulty score)
A 26-year-old man undergoes an abdominal exploratory ...
Splenic

Block/Question (24.3 difficulty score)
A 17-year-old girl comes to the emergency department because ...
Speak with the patient and her parents about the findings

Block/Question (46.2 difficulty score)
Following a wedding reception that was attended by 75 people, ...
Norovirus

Block/Question (44.5 difficulty score)
An investigator compares the DNA sequences of a group of ...
5′ CCGG

Block/Question (17.6 difficulty score)
A 56-year-old woman has frequently burned herself while ...
Syrinx of the central region of the spinal cord from C-4 to T-5

Block/Question (26.0 difficulty score)
A 32-year-old woman has had fecal incontinence since giving ...
Damage to the anal sphincter

Block/Question (61.7 difficulty score)
An 18-year-old boy has just been diagnosed with ...
50%

Block/Question (51.5 difficulty score)
A 30-year-old man comes to the physician because of a 3-month ...
Increased osteoclast maturation and activity

Block/Question (45.7 difficulty score)
Three elderly residents of an assisted living facility in ...
Legionella pneumophila

Block/Question (24.1 difficulty score)
An otherwise healthy 16-year-old girl comes to the physician ...
Cold, dry air

Block/Question (30.9 difficulty score)
A 70-year-old woman is transferred to a rehabilitative ...
Activity level before the fracture

Block/Question (34.4 difficulty score)
A female newborn delivered at 36 weeks' gestation is in ...
Incomplete formation of pleuroperitoneal membrane

Block/Question (37.4 difficulty score)
An 80-year-old man with type 2 diabetes mellitus is brought ...
Pelvic splanchnic

Block/Question (35.3 difficulty score)
A 25-year-old woman comes to the physician because of a 2-day ...
A phospholipid (cardiolipin) on charcoal particles

Block/Question (34.2 difficulty score)
A 23-year-old woman has had fever, hypotension, and ...
Streptococcus pneumoniae

Block/Question (26.1 difficulty score)
A 55-year-old man comes to the physician because of ...
Dextromethorphan

Block/Question (22.5 difficulty score)
A 10-year-old boy with mild mental retardation is brought to ...
Tuberous sclerosis

Block/Question (49.1 difficulty score)
A 57-year old man has a hemoglobin concentration of 18.5 ...
Chronic obstructive pulmonary disease

Block/Question (25.2 difficulty score)
A 65-year-old man is brought to the emergency department ...
ST-segment elevation

Block/Question (49.4 difficulty score)
A 66-year-old man is brought to the emergency department 30 ...
Cigarette smoking

Block/Question (44.2 difficulty score)
A 19-year-old man who is a college student is brought to the ...
Subcutaneous crepitus

Block/Question (40.2 difficulty score)
A 25-year-old woman comes to the physician 2 days after ...
Granulomas containing stellate microabscesses

Block/Question (29.0 difficulty score)
A 44-year-old woman comes to the physician for a follow-up ...
Ubiquitin ligase

Block/Question (33.2 difficulty score)
Which of the following changes in the cardiovascular system ...
Increased basal systolic blood pressure

Block/Question (24.0 difficulty score)
A patient with a 1-week history of diarrhea has reduced ...
Decreased arterial Pco2

Block/Question (45.0 difficulty score)
A 14-year-old girl is brought to the physician because of a ...
Mitochondrial tRNALeu

Block/Question (43.5 difficulty score)
A male newborn is found to have a decreased blood thyroxine ...
Thyroid hormone-binding globulin deficiency

Block/Question (23.1 difficulty score)
A 38-year-old African American man with recently diagnosed ...
It should play a role because the efficacy of certain classes of medications varies among different ethnicities

Block/Question (25.3 difficulty score)
At a postnatal checkup, a 6-week-old female newborn weighs 20 ...
Annular pancreas

Block/Question (31.2 difficulty score)
A 25-year-old woman has a flu-like illness (fever, myalgias, ...
Picornavirus

Block/Question (46.1 difficulty score)
A 78-year-old man is brought to the emergency department by ...
Cortisol

Block/Question (33.0 difficulty score)
A 25-year-old man comes to the physician 8 hours after the ...
Rupture of an intervertebral disc

Block/Question (54.7 difficulty score)
A 12-year-old girl is brought to the physician by her mother ...
Osteoblasts

Block/Question (12.9 difficulty score)
A study is conducted to assess the effect of a new screening ...
Lead-time

Block/Question (20.7 difficulty score)
A 28-year-old man has excessive thirst and polyuria. The ...
Hypothalamus

Block/Question (54.6 difficulty score)
A 36-year-old woman comes to the office because of a 1-month ...
Splenomegaly

Block/Question (27.8 difficulty score)
A 31-year-old man has a large, yellow, soft mass deeply ...
Liposarcoma

Block/Question (32.9 difficulty score)
A 28-year-old woman of Eastern European Jewish decent comes ...
Recombinational double-stranded DNA break repair

Block/Question (20.5 difficulty score)
A 50-year-old woman with a restrictive pulmonary disorder ...
Functional residual capacity: decreased; Residual volume: decreased; Vital capacity: decreased

Block/Question (23.8 difficulty score)
A 29-year-old man comes to the physician because of a 1-week ...
Absence of peptidoglycan

Block/Question (21.3 difficulty score)
A 70-year-old man has a 3-month history of weakness and a ...
Squamous cell carcinoma

Block/Question (48.6 difficulty score)
Purified serum antibodies elicited by immunization with ...
Proteins X and Y express the same epitopes

Block/Question (29.4 difficulty score)
A previously healthy 32-year-old woman is brought to the ...
Preload

Block/Question (45.5 difficulty score)
An 18-year-old woman comes to the physician because she has ...
Ovaries

Block/Question (28.6 difficulty score)
A 43-year-old woman, gravida 2, para 1, at 10 weeks' ...
Nuchal translucency (fetal ultrasound): increased;
Pregnancy-associated Plasma Protein (maternal serum): decreased;
Human Chorionic Gonadotropin (maternal serum): increased


Block/Question (24.4 difficulty score)
A new antiplatelet agent is developed for the prevention of ...
8%

Block/Question (25.0 difficulty score)
A physician prescribes a newly marketed drug to 45 patients. ...
Discontinue the new drug in affected patients and file MedWatch reports on the FDA's Web site

Block/Question (39.5 difficulty score)
A 35-year-old man comes to the physician to discuss donating ...
1:4

Block/Question (42.0 difficulty score)
A sedentary 50-year-old man with hypertension comes to the ...
Antidepressant therapy

Block/Question (36.8 difficulty score)
An 82-year-old woman is brought to the physician because of a ...
Decreased slope of diastolic depolarization

Block/Question (30.1 difficulty score)
A 27-year-old woman comes to the physician because of a ...
Pheochromocytoma

Block/Question (43.1 difficulty score)
The frequency of an autosomal recessive disease in a ...
1/25

Block/Question (30.0 difficulty score)
A 23-year-old woman is brought to the emergency department ...
Xanthine oxidase

Block/Question (17.3 difficulty score)
A 45-year-old woman has a thyroidectomy because of asymmetric ...
Calcitonin

Block/Question (34.3 difficulty score)
An 18-year-old woman comes to the physician because of fever, ...
Reactive T lymphocytes

Block/Question (27.2 difficulty score)
A 35-year-old man comes to the physician because of a 2-month ...
Methotrexate

Block/Question (16.6 difficulty score)
A new drug has the following effects on the activity of the ...
Pathway labeled 'H' (Conversion of Leukotriene A4 to Leukotriene B4

Block/Question (28.9 difficulty score)
A 10-year-old boy has a palpable mass in the ventral midline ...
Endoderm of foramen caecum

Block/Question (27.0 difficulty score)
A 12-year-old girl is brought to the physician for a ...
Polyubiquitination

Block/Question (21.8 difficulty score)
A 62-year-old man comes to the physician because of pain in ...
Prostate

Block/Question (23.1 difficulty score)
A 59-year-old man develops fatigue and decreased appetite 3 ...
Hemolysis

Block/Question (50.7 difficulty score)
A 3-year-old boy is brought to the physician because of a ...
Heterozygous mutation in the ankyrin gene

Block/Question (20.5 difficulty score)
A 46-year-old man has dyspnea, orthopnea, and a midsystolic ...
Mitral regurgitation

Block/Question (24.3 difficulty score)
A 45-year-old woman develops proteinuria and hematuria. She ...
Tubulointerstitial nephritis

Block/Question (16.4 difficulty score)
During a clinical study, an investigator tests a new drug for ...
Increase the sample size

Block/Question (30.8 difficulty score)
A 23-year-old woman, who was diagnosed with Sjögren syndrome ...
Substance P

Block/Question (10.3 difficulty score)
A 41-year-old woman with systemic lupus erythematosus is ...
Ask the attending physician to obtain informed consent

Block/Question (11.8 difficulty score)
A 45-year-old man comes to the emergency department because ...
Schizoid personality disorder

Block/Question (40.4 difficulty score)
An 18-year-old woman comes to the physician to request ...
50%

Block/Question (33.2 difficulty score)
A 23-year-old man comes to the physician because of a 1-month ...
Area labeled ‘B’ (Mitochondrion)

Block/Question (35.6 difficulty score)
A 67-year-old woman comes to the physician for a health ...
Low sensitivity

Block/Question (25.8 difficulty score)
A newborn is born with a lethal chromosome defect. He is ...
Feed by whatever means necessary to maintain comfort

Block/Question (22.5 difficulty score)
In patients with breast cancer, metabolically stable agonists ...
Gonadotropin by the pituitary gland

Block/Question (64.1 difficulty score)
A 50-year-old woman is brought to the emergency department by ...
pKa: 6.0; Protein binding in plasma: 20%; Volume of distribution at steady state: 1 L/kg

Block/Question (29.2 difficulty score)
A 2-month-old girl is brought to the emergency department by ...
Thyroid function tests

Block/Question (19.6 difficulty score)
A 4-week-old infant is brought to the emergency department ...
Hypertrophic pyloric stenosis

Block/Question (27.1 difficulty score)
A 3-month-old boy is brought to the physician because of ...
Mannose 6-phosphate

Block/Question (12.7 difficulty score)
A 55-year-old man with type 2 diabetes mellitus, ...
Pravastatin

Block/Question (22.5 difficulty score)
A 23-year-old woman who is 6 months pregnant develops deep ...
Antiplatelet antibodies

Block/Question (25.1 difficulty score)
An 83-year-old man is brought to the emergency department ...
Early septic shock

Block/Question (27.2 difficulty score)
A 22-year-old woman who recently emigrated from rural Mexico ...
Obstruction of the right interventricular foramen (foramen of Monro)

Block/Question (18.8 difficulty score)
A 62-year-old woman comes to the physician because of ...
β-Tubulin

Block/Question (15.6 difficulty score)
A 54-year-old woman with terminal metastatic pancreatic ...
Nonmaleficence

Block/Question (19.2 difficulty score)
A 31-year-old woman receives a prescription for tetracycline ...
Formation of complexes with mineral ions

Block/Question (16.8 difficulty score)
A 22-year-old woman comes to the emergency department because ...
Release of bacterial products

Block/Question (37.7 difficulty score)
A 51-year-old man has the acute onset of fever and ...
Cytomegalovirus infection

Block/Question (45.0 difficulty score)
A 4-year-old boy has had fever, abdominal cramping, and ...
Shigella sonnei

Block/Question (31.7 difficulty score)
A 62-year-old man with alcohol-induced liver disease develops ...
Spironolactone

Block/Question (39.7 difficulty score)
A 23-year-old man with a 3-year history of schizophrenia is ...
Psychogenic polydipsia

Block/Question (38.6 difficulty score)
A 19-year-old woman has severe refractory pustular acne that ...
Teratogenic effects in the embryo

Block/Question (15.6 difficulty score)
Two days after admission to the hospital because of ...
Do not proceed with the transfusion

Block/Question (39.2 difficulty score)
A 2-year-old child undergoes resection of the right kidney ...
Increase in glomerular size

Block/Question (38.2 difficulty score)
A 13-year-old girl has an episode of severe cellular ...
Epstein-Barr virus genome

Block/Question (23.4 difficulty score)
A 71-year-old man comes to the physician because of a 6-month ...
Cilostazol

Block/Question (44.9 difficulty score)
A 56-year-old man is brought to the emergency department 30 ...
Capillary hydrostatic: increased; Interstitial hydrostatic: increased; Interstitial oncotic: decreased

Block/Question (21.8 difficulty score)
A 39-year-old man reports bright red spots on the toilet ...
Constipation

Block/Question (36.6 difficulty score)
Removal of the thymus at birth results in severely impaired ...
Thymic lymphocytes produced before thymectomy are long-lived

Block/Question (33.8 difficulty score)
A 60-year-old woman has prolonged apnea following general ...
Succinylcholine

Block/Question (19.2 difficulty score)
A 48-year-old woman comes to the physician because of a ...
Hypothyroidism

Block/Question (42.6 difficulty score)
A 92-year-old woman who was recently admitted to a nursing ...
Atrophy of dermal collagen

Block/Question (34.3 difficulty score)
A 62-year-old man comes to the physician because of a 1-week ...
Agonist at γ-aminobutyric acid B (GABAB) receptors

Block/Question (38.9 difficulty score)
A 32-year-old man comes to the physician because of a 3-month ...
Tissue: testicle; Effect: estradiol production

Block/Question (17.1 difficulty score)
A study is conducted to identify healthy women at risk for ...
Liver

Block/Question (36.5 difficulty score)
A 23-year-old woman comes to the physician for a follow-up ...
Collagen synthesis

Block/Question (28.2 difficulty score)
A 20-year-old man comes to the physician stating that food ...
Olfactory

Block/Question (27.2 difficulty score)
Immediately after a cerebral infarction, a 62-year-old ...
Area labeled ‘A’ (Broca’s area)

Block/Question (19.9 difficulty score)
A 51-year-old man develops diaphoresis, tachycardia, and a ...
Alcohol withdrawal

Block/Question (35.4 difficulty score)
A 33-year-old woman with HIV infection is brought to the ...
Non-Hodgkin lymphoma

Block/Question (35.0 difficulty score)
A 58-year-old man is brought to the emergency department ...
Hypertension

Block/Question (22.0 difficulty score)
A previously healthy 37-year-old woman comes to the physician ...
Tumor of the adrenal zona fasciculata

Block/Question (27.0 difficulty score)
A 65-year-old woman who has a 25-year history of chronic ...
Hydroxylation of proline

Block/Question (28.1 difficulty score)
A 37-year-old man who is HIV positive comes to the physician ...
Nortriptyline

Block/Question (33.5 difficulty score)
An investigator is conducting a randomized, double-blind, ...
Analyze all nonadherent participants according to the group of the study to which each was randomized

Block/Question (52.3 difficulty score)
A 62-year-old woman comes to the physician because of a ...
Bronchogenic carcinoma

Block/Question (24.5 difficulty score)
A 60-year-old man has a round, semitransparent nodule on his ...
Basal cell carcinoma

Block/Question (37.4 difficulty score)
A 45-year-old man is undergoing a surgical procedure. Which ...
Decreasing respiratory rate

Block/Question (45.5 difficulty score)
An investigator wishes to determine the effectiveness of a ...
Ductal ion reabsorption is more efficient at low flow rates

Block/Question (28.8 difficulty score)
A previously healthy 55-year-old man has recently been ...
Renal artery stenosis

Block/Question (30.8 difficulty score)
A 35-year-old man comes to the physician because of a 6-month ...
Gastrin

Block/Question (24.2 difficulty score)
A 55-year-old man with severe emphysema comes to the ...
Percussion: hyperresonant; Tactile fremitus: decreased; Expiratory phase: prolonged

Block/Question (38.4 difficulty score)
A 5-year-old boy is brought to the physician for a follow-up ...
Hypophosphatemia

Block/Question (60.9 difficulty score)
A 47-year-old woman comes to the physician because of a ...
Contact with parakeets

Block/Question (23.6 difficulty score)
A 35-year-old man is given cyclosporine following a liver ...
Decreased synthesis of interleukins

Block/Question (12.6 difficulty score)
A 45-year-old woman who is intubated and mechanically ...
β-Glucan carbohydrates in the cell wall

Block/Question (36.5 difficulty score)
A 27-year-old man comes to the physician because of weakness ...
Deep branch of the ulnar nerve at the hook of the hamate bone

Block/Question (39.8 difficulty score)
A 52-year-old man is brought to the emergency department ...
Increased total peripheral resistance and decreased cardiac output

Block/Question (32.1 difficulty score)
A 33-year-old man comes to the physician because of a 3-week ...
Rectus femoris

Block/Question (29.2 difficulty score)
An investigator is studying patients with West Nile virus ...
Case series

Block/Question (40.8 difficulty score)
A 78-year-old man dies of chronic congestive heart failure. ...
Failure of the Na+–K+ pump

Block/Question (25.0 difficulty score)
A 15-year-old girl is brought to the physician by her mother ...
Doxycycline

Block/Question (27.1 difficulty score)
A 32-year-old woman is brought to the emergency department 20 ...
Arterial laceration

Block/Question (37.9 difficulty score)
A 48-year-old man is brought to the emergency department 12 ...
Cl-: 96 mEq/L; HCO3-: 8 mEq/L

Block/Question (44.4 difficulty score)
A 55-year-old man comes to the physician because of a 2-month ...
Partial oxidation of fatty acids

Block/Question (25.7 difficulty score)
A 65-year-old woman with cardiovascular disease is found to ...
Increased bile salt

Block/Question (13.7 difficulty score)
A 20-year-old man is brought to the physician by his mother ...
How frightening for you to see your son like this. Do you have any idea about what might be causing his behavior?""

Block/Question (13.6 difficulty score)
A 62-year-old man comes to the physician for a follow-up ...
Contemplation

Block/Question (20.4 difficulty score)
A 25-year-old woman is brought to the emergency department ...
Factitious disorder

Block/Question (25.8 difficulty score)
A 16-year-old girl with cystic fibrosis is brought to the ...
Vitamin E

Block/Question (20.0 difficulty score)
A 45-year-old man comes to the physician because of ...
Tumor necrosis factor

Block/Question (20.2 difficulty score)
A 30-year-old woman develops serum sickness following ...
C3a

Block/Question (23.1 difficulty score)
A 6-month-old girl is brought to the emergency department by ...
Ornithine transcarbamylase

Block/Question (38.6 difficulty score)
A 56-year-old man with a 20-year history of chronic back pain ...
Naloxone

Block/Question (56.9 difficulty score)
A 65-year-old woman dies 6 months after the onset of severe ...
Meningeal

Block/Question (38.5 difficulty score)
A physician is assigned to a search and rescue team ...
Negative nitrogen balance

Block/Question (48.2 difficulty score)
A 45-year-old man comes to the office for counseling prior to ...
Starchy foods

Block/Question (12.4 difficulty score)
A 12-year-old boy is brought to the physician for further ...
Terminal components of complement

Block/Question (64.7 difficulty score)
A 28-year-old woman at 32 weeks' gestation comes to the ...
Obstructive uropathy

Block/Question (24.9 difficulty score)
A 61-year-old man has erectile dysfunction due to spinal cord ...
Area labeled ‘D’ (Corpus cavernosum)

Block/Question (32.4 difficulty score)
A 24-year-old man comes to the emergency department because ...
Lipoprotein lipase

Block/Question (39.8 difficulty score)
A 23-year-old woman sustains significant blood loss in a ...
Direct antiglobulin test

Block/Question (15.7 difficulty score)
A previously healthy 16-year-old girl is brought to the ...
Prescribe antibiotics without notifying her parents

NBME 19

Block/Question (18.2 difficulty score)
53 yo woman w/GERD. Diet change, stress reduction do not ...
Omeprazole

Block/Question (21.3 difficulty score)
66 yo man, 2 months of not being able to maintain an ...
Libido: decreased; Noctural erections: normal

Block/Question (7.6 difficulty score)
48 yo woman, 2 weeks of fever and stool with mucus; recent ...
Entamoeba histolytica

Block/Question (11.6 difficulty score)
What mechanism of action do tumor-suppressor genes have that ...
Inhibition of cell-cycle regulation

Block/Question (4.7 difficulty score)
60 yo man, 2 week history of flank pain and blood in urine. ...
Metastatic renal cell carcinoma

Block/Question (10.1 difficulty score)
29 yo man with untreated HIV infection; what explains ...
CD8+ T lymphocyte–mediated killing

Block/Question (9.7 difficulty score)
62 yo woman with sudden weakness of left leg; infarct in ...
Right anterior cerebral artery

Block/Question (9.2 difficulty score)
Niemann-Pick disease is characterized by which of the following?
Decreased lysosomal hydrolase activity

Block/Question (4.3 difficulty score)
13 yo girl with mother for routine visit; physician wants to ...
Ask mother to leave the room before asking the patient any questions.

Block/Question (4.6 difficulty score)
32 yo man given primaquine for malaria prophylaxis; develops ...
Enzyme deficiency in the erythrocytes

Block/Question (4.2 difficulty score)
12 yo girl unable to walk for 5 days but is unconcerned about ...
Conversion disorder

Block/Question (26.0 difficulty score)
5 yo boy, R eye pain for 1 week; retinal exam shows a mass. ...
Retinal cells

Block/Question (3.5 difficulty score)
36 yo woman presents to ED after believing she suffered a ...
Panic disorder

Block/Question (8.6 difficulty score)
What advantage does randomized controlled study have over ...
Better control for confounding variables

Block/Question (4.5 difficulty score)
Three tests are developed to identify rotavirus in children ...
Test 3 followed by test 1 if test 3 is positive

Block/Question (7.6 difficulty score)
62 yo man, right-handed, suffers decreased speech fluency ...
Area labeled by letter 'A'

Block/Question (5.2 difficulty score)
38 yo woman, 6 months depressed mood, joint pain, weakness, ...
Lyme disease

Block/Question (4.3 difficulty score)
24 yo man, generalized tonic-clonic seizure; somnolent, ...
Psychogenic polydipsia

Block/Question (5.1 difficulty score)
Retinoic acid receptors and HOX gene products bind specific ...
Transcription factors

Block/Question (4.2 difficulty score)
Lab findings expected after administration of insulin and saline
Potassium decreased; Bicarbonate increased; BUN decreased; Arterial pH increased; blood CO2 increased

Block/Question (10.2 difficulty score)
25 yo man, exercise test. Most likely physiologic changes
Arteriolar diameter increased; Tissue adenosine concentration increased; Vascular conductance increased

Block/Question (13.2 difficulty score)
40 yo woman, chorionic villus sampling
Confined placental mosaicism

Block/Question (4.2 difficulty score)
Scurvy symptoms associated with decreased activity of which ...
Prolyl hydroxylase

Block/Question (7.4 difficulty score)
10 yo girl, slightly painful 2 mm subcutaneous nodule on chin
Granuloma

Block/Question (5.8 difficulty score)
48 yo woman, 3 months fatigue; X-rays reveal generalized ...
Paracrine stimulation of osteoclasts by osteoblasts

Block/Question (4.0 difficulty score)
Case-control study; 95 percent confidence interval was ...
The likelihood is 95% that the true value for the odds ratio is between [the reported range]

Block/Question (3.2 difficulty score)
Mechanism by which action potentials permit currents to flow ...
Transmission along T tubules

Block/Question (3.8 difficulty score)
75 yo man with dementia; no advanced directives
Encourage the family to come to a consensus based on their perception of the patient's wishes

Block/Question (4.2 difficulty score)
2 day old newborn with jaundice
Conjugation of bilirubin to glucuronic acid

Block/Question (3.8 difficulty score)
45 yo woman undergoing vinblastine chemotherapy
Decreased number of neutrophils

Block/Question (6.1 difficulty score)
Pathway of the transepithelial transport of water
Pathway denoted by letter 'C'

Block/Question (3.9 difficulty score)
Decreased pulmonary artery pressure facilitated by increase ...
cGMP

Block/Question (9.2 difficulty score)
30 yo woman, 1 week of visual difficulty
Right optic nerve

Block/Question (5.7 difficulty score)
Cells most responsible for graft rejection?
T lymphocytes

Block/Question (10.2 difficulty score)
23 yo woman engages in 30 minutes of strenuous exercise
Increased, as a result of distention and recruitment of microvessels

Block/Question (7.3 difficulty score)
13 yo girl grows over the summer; what accounts for increased ...
Hormones derived from 7-dehydrocholesterol

Block/Question (6.5 difficulty score)
45 yo patient, chronic alcohol dependence, foul-smelling ...
Chest radiograph labeled 'D'

Block/Question (9.9 difficulty score)
30 yo man and 24 yo woman; best estimate that child will have ...
1 in 600

Block/Question (6.1 difficulty score)
Blood gas values: arterial O<sub>2</sub> pressure: 96 mm Hg; ...
Anemia

Block/Question (6.0 difficulty score)
74 yo man; continuous systolic-diastolic bruit over R ...
Renal artery stenosis

Block/Question (5.5 difficulty score)
40 yo man, 1 month increasing malaise, nausea, abdominal ...
Hepatocytes

Block/Question (4.8 difficulty score)
15 yo girl receives bone marrow transplant; karyotype reveals ...
Nonautologous donor

Block/Question (3.9 difficulty score)
19 yo man stabbed in abdomen; has been incarcerated for armed ...
Antisocial personality disorder

Block/Question (6.1 difficulty score)
52 yo man, 4 hours of severe headache, anxiety, sweating, ...
Increased total peripheral resistance and decreased cardiac output

Block/Question (6.5 difficulty score)
45 yo man, lost outdoors in the Rocky Mountains for 10 days
Kidney

Block/Question (8.6 difficulty score)
25 yo woman requests prenatal diagnosis at 12 weeks gestation
Chorionic villi sampling

Block/Question (5.8 difficulty score)
41 yo woman, 34 weeks gestation; amniocentesis shows ...
Decreased functional residual capacity

Block/Question (9.8 difficulty score)
Study conducted to determine effects of drug X on respiratory ...
Tubocurarine

Block/Question (5.3 difficulty score)
52 yo man, sudden onset of substernal chest pain
Histamine

Block/Question (6.8 difficulty score)
Schematic representation of eukaryotic translation
Binding of aminoacyl-tRNA to the A site

Block/Question (6.0 difficulty score)
39 yo man, 6 months of headache, muscle aches, fatigue; ...
Basophilic stippling

Block/Question (3.3 difficulty score)
26 yo woman after jejunoileal bypass for morbid obesity; most ...
Vitamin A

Block/Question (4.1 difficulty score)
11 yo boy, right mid-thigh pain for 2 weeks; femur X-ray ...
Ewing sarcoma

Block/Question (4.6 difficulty score)
60 yo woman, 1 year of episodic involuntary rhythmic jerking ...
Meningioma

Block/Question (6.3 difficulty score)
60 yo man, 20-year history of hypertension; shortness of ...
Cardiac output: decreased; CVP: increased

Block/Question (6.9 difficulty score)
30 yo woman with Marfan syndrome, sudden onset of tearing ...
Cardiac index: 2.0;
Right atrial pressure: 18;
Pulmonary capillary wedge pressure: 18;
Pulmonary diastolic arterial pressure: 20;
Systemic vascular resistance: 2,000


Block/Question (4.6 difficulty score)
54 yo man, routine exam; given an angiotensin converting ...
Area labeled by letter 'F' (efferent arteriole)

Block/Question (4.3 difficulty score)
52 yo woman prescribed cisplatin for non-small cell carcinoma ...
Odansetron

Block/Question (6.9 difficulty score)
Oral fluid therapy for diarrhea caused by <i>Vibrio cholerae</i>
Membrane transport mechanism denoted by letter 'C' (Sodium-Glucose cotransporter)

Block/Question (7.7 difficulty score)
24 yo woman; renal oxygen consumption found to be 20 mL per ...
Tubular reabsorption

Block/Question (4.2 difficulty score)
30 yo woman with high-grade intraepithelial lesion
Superficial to the basement membrane

Block/Question (4.7 difficulty score)
A 27-year-old woman has an episode of pneumococcal pneumonia ...
Direct antiglobulin (Coombs) test

Block/Question (7.9 difficulty score)
During an experiment, an isolated skeletal muscle is placed ...
pH

Block/Question (1.7 difficulty score)
A newborn delivered at term to a 40-year-old...following hormones?
Testosterone

Block/Question (1.8 difficulty score)
80 year old woman...progressive shortness of breath...dicumarol
Induces a vitamin K deficiency-like state

Block/Question (1.1 difficulty score)
A 43-year-old woman...aspirin...most likely inhibited?
"B" step converting arachidonic acid to prostaglandin G2

Block/Question (1.2 difficulty score)
48-year-old man admitted for idiopathic pulmonary hypertension...
Right ventricular afterload

Block/Question (1.5 difficulty score)
Investigator studying spermatogenesis...tight junctions disrupted
Sertoli

Block/Question (1.8 difficulty score)
23-year-old woman...heparin...decreased platelet count
Antiplatelet antibodies

Block/Question (1.9 difficulty score)
76-year-old-man...severe substernal chest pain...argument
Coronary vasospasm due to alpha1-adrenergic stimulation

Block/Question (2.2 difficulty score)
Graph shows rate of breakdown of skeletal muscle glycogen... AMP
Allosteric activator

Block/Question (1.4 difficulty score)
During an experiment, a researcher blocks the production... dynein
Retrograde axonal transport

Block/Question (0.7 difficulty score)
Investigator does an experiment... third pharyngeal pouches
Thymus

Block/Question (1.2 difficulty score)
A 2-year-old boy with cerebral palsy is scheduled...
obturator

Block/Question (1.1 difficulty score)
An 11-year-old boy has repeated episodes of staphylococcal..
NADPH oxidase

Block/Question (1.8 difficulty score)
An investigator studying the function of a voltage-gated..
decreases the amplitude of the action potential

Block/Question (1.7 difficulty score)
A 35-year-old man comes to the physician to discuss donating....
1:4

Block/Question (2.1 difficulty score)
A 30-year-old man develops urinary incontinence 2 weeks...
pelvic nerves

Block/Question (3.3 difficulty score)
A 70-year-old man develops a progressive disinhibiton....
Frontal lobe disinhibition

Block/Question (2.3 difficulty score)
Immediately after cerebral infarction, a 62-year-old right-handed
A (Broca's area)

Block/Question (1.4 difficulty score)
In the diagram of the proximal renal tubular epithelium, the label
C (no carriers, going from lumen to basolateral side)

Block/Question (0.9 difficulty score)
A 33-year-old woman has had weakness of the right lower two thirds
C (face portion - MCA - of primary motor homonculus)

NBME 18

Block/Question (33.5 difficulty score)
5 yo boy, history of motion sickness
Antagonist at muscarinic-3 receptors

Block/Question (15.4 difficulty score)
25 yo woman, polycystic kidneys
HCO3: decreased; inorganic PO4: increased; parathryroid hormone: increased

Block/Question (8.8 difficulty score)
67 yo man, fine resting tremor in both hands
Alpha-synuclein

Block/Question (13.0 difficulty score)
10 yo boy, nosebleeds and easy bruising
Antibodies directed against the glycoprotein (Gp) IIb/IIIa complex

Block/Question (22.8 difficulty score)
26 yo man with 27 yo wife, inability to conceive
Primary spermatocyte

Block/Question (14.0 difficulty score)
experimental animal with defect in an innate gastrointestinal ...
Chronic gastritis

Block/Question (10.3 difficulty score)
4 day old boy, vomited throughout night after breastfeeding
21-Hydroxylase

Block/Question (11.7 difficulty score)
68 yo man, chronically increased hydrostatic pressure in ...
Benign prostatic hyperplasia

Block/Question (11.3 difficulty score)
70 yo woman, increasingly severe pain in right knee over 3 months
Pleomorphic neoplastic cells producing new woven bone

Block/Question (8.8 difficulty score)
22 yo man, professional cyclist
Eccentric hypertrophy

Block/Question (12.8 difficulty score)
50 yo woman, chronic obstructive pulmonary disease
Endothelial nitric oxide synthase production

Block/Question (6.4 difficulty score)
Cholera toxin is a catalyst that results in the inhibition of ...
Concentration of cAMP

Block/Question (9.5 difficulty score)
29 yo woman irregular menstrual periods
Provide follow-up appointments to assess the patient's progress in attaining her goals

Block/Question (12.2 difficulty score)
7 yo boy appendectomy
Low blood solubility

Block/Question (16.0 difficulty score)
52 yo man with chest pain and shortness of breath
Proximal tubule: isotonic; Macula densa: hypotonic; Medullary collecting duct: hypertonic

Block/Question (13.0 difficulty score)
35 yo woman with pain and swelling of breasts, pelvic discomfort
Have a chaperone join them for the remainder of the examination

Block/Question (12.7 difficulty score)
60 yo man, 1 day of fever, chills, confusion and memory loss
Vibrio vulnificus

Block/Question (8.5 difficulty score)
45 yo homeless man found unconscious
Methylmalonic Acid: normal; Homocysteine: increased

Block/Question (9.8 difficulty score)
18 yo man cracked lips and sunburned skin
Barrier

Block/Question (4.9 difficulty score)
26 yo man skiing accident
Axillary

Block/Question (19.0 difficulty score)
55 yo man; father and brother died of myocardial infarct at ...
Increased transcription of HMG-CoA reductase

Block/Question (6.7 difficulty score)
65 yo man, generalized tonic-clonic seizures
High-grade fibrillary astrocytoma

Block/Question (15.8 difficulty score)
39 yo man, polycystic kidney disease
pH: 7.22; PCO2: 28; HCO2: 11

Block/Question (15.7 difficulty score)
19 yo woman being treated for meningococcal meningitis
Adrenocorticotropic hormone stimulation test

Block/Question (8.5 difficulty score)
38 yo man, 1 week history of shortness of breath with exertion
Aortic regurgitation

Block/Question (18.5 difficulty score)
65 yo woman, 1 week of swollen, painful knee
Uric acid

Block/Question (10.2 difficulty score)
Researcher testing new cancer drug
Neutrophil counts

Block/Question (16.0 difficulty score)
66 yo woman, 2 days of fever, flank pain, pain with ...
Calcium carbonate

Block/Question (21.6 difficulty score)
40 yo man, 1 year of orthostatic hypotension and loose stools
Motility disorder

Block/Question (18.6 difficulty score)
58 yo man, 4 years of recurrent cough and sputum
Pseudostratified columnar epithelial cells

Block/Question (6.4 difficulty score)
32 yo woman, new neurologic finding; imaging shows cavernous ...
Inability to abduct the eye

Block/Question (17.4 difficulty score)
35 yo man, 4 weeks of severe midline back pain
ACTH

Block/Question (19.2 difficulty score)
Investigator studying vancomycin-resistant <i>Enterococcus ...
Plasmid loss

Block/Question (18.9 difficulty score)
25 yo woman, fatigue for 3 weeks
Greening reaction on blood agar

Block/Question (10.9 difficulty score)
34 yo man, semiconscious and combative
Pseudocholinesterase

Block/Question (8.1 difficulty score)
35 yo woman, 3 days fever and sharp chest pain
Virus

Block/Question (8.3 difficulty score)
35 yo woman, passed out while washing dishes
K+: decreased; HCO3: increased; Anion gap: normal; pH: increased

Block/Question (8.1 difficulty score)
17 yo boy septic shock
alpha-1-Adrenoreceptors

Block/Question (26.5 difficulty score)
82 yo woman, 24 hours of constant severe lower abdominal pain
Fibrin

Block/Question (8.4 difficulty score)
32 yo woman, diagnosis of hyperparathyroidism
Abnormal migration of endoderm from the fourth pharyngeal pouch

Block/Question (17.9 difficulty score)
35 yo woman with infertility
Spillage of contrast, which is normal

Block/Question (9.6 difficulty score)
58 yo woman, 6 months shortness of breath, nonproductive cough
Pulmonary hypertension

Block/Question (7.3 difficulty score)
35 yo woman, 2 days pain in left leg
Drug-related antibodies

Block/Question (11.1 difficulty score)
2 yo boy, 2 days of fever, sore throat, rash
Erythrogenic toxin

Block/Question (9.2 difficulty score)
46 yo woman, 1 week of fever and joint pain
Inflammatory infiltrates in the interstitium

Block/Question (14.4 difficulty score)
48 yo woman, gradual onset of back pain over 2 weeks
Metastatic carcinoma of the breast

Block/Question (14.5 difficulty score)
70 yo woman routine pelvic examination
Cystocele

Block/Question (13.6 difficulty score)
63 yo man, 2 weeks of fullness in left upper quadrant of abdomen
Myelofibrosis

Block/Question (19.2 difficulty score)
33 yo man, diagnosed with epilepsy
He is medically qualified to drive

Block/Question (12.3 difficulty score)
28 yo woman, 4 days of palpitations, severe neck pain, ...
Subacute granulomatous thyroiditis

Block/Question (18.5 difficulty score)
25 yo woman, 2 years of intermittent, diffuse, cramping lower ...
Accentuation of mu-opioid myenteric plexus receptor

Block/Question (13.5 difficulty score)
4 yo boy, clumsy gait for 1 year
1/4

Block/Question (18.2 difficulty score)
52 yo woman with breast cancer
Contraction

Block/Question (14.0 difficulty score)
47 yo woman with irregular, raised, multicolored dark lesion
Subcutaneous tissue

Block/Question (24.0 difficulty score)
24 yo man, 3 days of progressive numbness of both feet
Myelinated primary afferents

Block/Question (12.8 difficulty score)
65 yo patient with lung region underventilated but well perfused
Physiologic shunt

Block/Question (10.9 difficulty score)
45 yo man for annual health maintenance examination
Fenofibrate

Block/Question (11.4 difficulty score)
19 yo woman, 2 days of pain in left index finger
Flexor digitorum profundus tendon

Block/Question (15.1 difficulty score)
52 yo man, chronic pancreatitis
Colipase

Block/Question (12.9 difficulty score)
68 yo man, 3 days of increasingly severe deep chest pain
Aortic aneurysm

Block/Question (20.7 difficulty score)
36 yo woman, 2 weeks of fatigue, bleeding gums, bone pain
Histone acetylase

Block/Question (8.9 difficulty score)
18 yo woman ingests 100 aspirin tablets in suicide attempt
pH: 7.32; PCO2: 15; HCO3: 8

Block/Question (10.5 difficulty score)
45 yo man follows up 1 week after appendectomy
Gilbert syndrome

Block/Question (9.7 difficulty score)
54 yo man, normal renal function, receives heart transplant
Cyclosporine

Block/Question (10.1 difficulty score)
65 yo man, cancer of the cecum
Ileocolic → superior mesenteric → portal → right hepatic branch of the portal

Block/Question (10.4 difficulty score)
5 yo girl, 1 day severe leg pain after falling off sled
Intestinal calcium absorption

Block/Question (11.5 difficulty score)
57 yo man with alcoholism
Liquefaction

Block/Question (9.9 difficulty score)
73 yo man, 4 months poor appetite and 25 pound weight loss
Cytokine effect

Block/Question (6.3 difficulty score)
18 yo woman given general anesthesia for wisdom tooth extraction
Sarcoplasmic Ca2+ release

Block/Question (9.8 difficulty score)
66 yo man, 1 month nonproductive cough, 6 months progressive ...
Idiopathic pulmonary fibrosis

Block/Question (9.5 difficulty score)
4 month old boy, abnormal glycogen storage
alpha-1,4-Glucosidase

Block/Question (10.9 difficulty score)
35 yo man, prolonged QT interval
Outward (delayed) rectifying potassium channel

Block/Question (2.7 difficulty score)
An investigator conduct a meta-analysis of three genome-wide assoc
The identified loci account for a relatively small part of the variance

Block/Question (2.3 difficulty score)
A 4-year-old boy, fatigue and irritability, eosinophils
Microcytic Anemia

Block/Question (1.4 difficulty score)
A 55-year-old woman who is a physician is admitted
Alcohol withdrawal

Block/Question (1.5 difficulty score)
an 83-year-old woman with systemic arteriolosclerosis undergoes
descending colon

Block/Question (3.1 difficulty score)
During a study of the regulation of cholesterol biosynthesis,
F (cell diagram)

Block/Question (2.4 difficulty score)
A 34-year-old man has a herniated lumbar intervertebral disc.
D (Lamina)

Block/Question (2.0 difficulty score)
A 51-year-old woman with Graves disease develops ulcerating
Agranulocytosis

Block/Question (1.5 difficulty score)
A 25-year old woman comes to the physician for counseling prior to
3 to 8 weeks

Block/Question (2.2 difficulty score)
A 17-year-old boy is brought to the physician by his mother
"Tell me more about your concerns about your son's height."

Block/Question (3.9 difficulty score)
A 68-year-old man comes to the physician because of a 10-month
Cor pulmonale

Block/Question (1.7 difficulty score)
A 30-year-old woman with a long standing history of pelvic
Macrophages

Block/Question (1.8 difficulty score)
During a clinical study of calcium and phosphorus metabolism, a 50
24,25-Dihydroxycholecalciferol

Block/Question (1.5 difficulty score)
A 4-year-old boy undergoes radiographic imaging studies of the
Tubular atrophy

Block/Question (1.4 difficulty score)
A 32-year-old man with an X-linked recessive disease has deafness
Type IV collagen

Block/Question (2.0 difficulty score)
A 45-year-old man comes to the physician for a preemployment
Transcription Factor c-Jun: increased; β-Myosin Heavy Chain: increased; Endothelin: increased

Block/Question (1.4 difficulty score)
36 yo woman, recently been diagnosed with HIV
Continue efavirens, emtricitabine, and tenofovir with no changes

Block/Question (1.3 difficulty score)
32 yo man, HIV infection comes to the physician
Reverse transcriptase and protease

Block/Question (0.8 difficulty score)
A 2 month old boy is brought to the physician
ventricular septal defect

Block/Question (0.9 difficulty score)
63 yo woman, 2-week history of daily episodes
Trigeminal neuralgia

Block/Question (1.7 difficulty score)
20 yo woman, 27 weeks' gestation
Inflamed maternal decidua release of prostaglandin

Block/Question (1.0 difficulty score)
A 1045-g (2-lb 5-oz) male newborn delivered at 28 weeks' gestation
Dipalmitoylphosphatidylcholine

Block/Question (1.0 difficulty score)
A 2-month-old female infant is admitted
Double-stranded RNA, segmented

Non-enveloped

Icosahedral capsid


Block/Question (0.6 difficulty score)
An 8 year old boy is suspended from school because...
methylpenidate

Block/Question (0.2 difficulty score)
35 year old ,precursor to uroporphrin... increased uroporphyrin
succinyl CoA

Block/Question (0.2 difficulty score)
35 year old ,precursor to uroporphrin... increased uroporphyrin
succinyl CoA

Block/Question (0.2 difficulty score)
MI study, 500 in operation, 250 each to 2 types of angioplasty
Randomized clinical trial

Block/Question (0.0 difficulty score)
a 35-year-old woman has congestive cardiomyopathy and pitting
prerenal azotemia

Block/Question (0.0 difficulty score)
a 67-year-old woman comes to the physician because of a 1-month
amyloid infiltration

NBME 17

Block/Question (14.8 difficulty score)
An 80-year-old woman is being evaluated for suspected ...
Additional testing to confirm the diagnosis of TA

Block/Question (6.3 difficulty score)
A 55-year-old man with chronic bronchitis is brought to the ...
Naloxone

Block/Question (12.9 difficulty score)
A 6-week-old girl is brought to the physician by her mother ...
Immature lower esophageal sphincter

Block/Question (6.6 difficulty score)
A 21-year-old man comes to the emergency department because ...
Inferior rectal vein

Block/Question (9.3 difficulty score)
A 24-year-old man with a history of intravenous drug use is ...
480

Block/Question (9.3 difficulty score)
A 42-year-old farmer has a 7-mm red scaly plaque on the ...
Actinic keratosis

Block/Question (10.7 difficulty score)
A 12-year-old boy is swimming in a mountain stream. He is ...
Central blood volume: increased; ADH (vasopressin): decreased; Atrial natriuretic peptide: increased

Block/Question (5.0 difficulty score)
A 42-year-old woman comes to the physician because of a ...
Rosacea

Block/Question (4.4 difficulty score)
A newborn has male genital ducts but female external ...
Scrotum

Block/Question (5.3 difficulty score)
A 9-year-old girl is brought to the physician because of poor ...
Diverticulum of the roof of the embryonic oral cavity

Block/Question (7.9 difficulty score)
A 28-year-old woman is brought to the physician because of a ...
Area labeled with letter 'C'

Block/Question (5.7 difficulty score)
A 56-year-old man comes to the physician 4 hours after the ...
Right subthalamic

Block/Question (5.1 difficulty score)
An 80-year-old woman comes to the emergency department ...
Hydrochlorothiazide

Block/Question (6.4 difficulty score)
A randomized clinical trial is conducted to compare wound ...
Neither procedure is superior

Block/Question (4.8 difficulty score)
A 13-year-old girl has a grade 2/6, holosystolic murmur that ...
Tricuspid

Block/Question (6.1 difficulty score)
A 2-month-old boy is given a vaccine that has been ...
Haemophilus influenzae type b

Block/Question (8.0 difficulty score)
A 28-year-old woman at 18 weeks' gestation has palpitations. ...
Free T4

Block/Question (3.9 difficulty score)
A 21-year-old man is brought to the emergency department 45 ...
Streptococcus pneumoniae

Block/Question (7.6 difficulty score)
A 38-year-old woman comes to the physician because of a ...
Proliferative endometrial tissue

Block/Question (5.8 difficulty score)
A 60-year-old man comes to the physician because of a 1-month ...
Pleural effusion

Block/Question (4.6 difficulty score)
A 65-year-old woman with ovarian cancer is treated with ...
DNA replication

Block/Question (7.8 difficulty score)
In a clinical study, a polymorphic marker with three alleles, ...
2,3

Block/Question (4.6 difficulty score)
A study is conducted to assess the effectiveness of ...
Placebo effect

Block/Question (6.8 difficulty score)
A 40-year-old man is evaluated because his skin is extremely ...
Heme synthesis

Block/Question (5.3 difficulty score)
A 40-year-old woman comes to the physician because of a ...
Sulfasalazine

Block/Question (5.9 difficulty score)
A 40-year-old man with interstitial pulmonary fibrosis has a ...
Increased radial traction on airways

Block/Question (4.2 difficulty score)
An investigator wishes to conduct a study of the development ...
Cohort

Block/Question (5.7 difficulty score)
A 25-year-old woman comes to the physician because of a ...
21-Hydroxylase

Block/Question (4.7 difficulty score)
A 38-year-old man is brought to the emergency department 30 ...
Metabolic acidosis

Block/Question (4.0 difficulty score)
A 3-year-old boy and his 5-year-old brother bruise easily and ...
Factor VIII (antihemophilic factor)

Block/Question (4.7 difficulty score)
A 40-year-old African American woman comes to the physician ...
1,25-Dihydroxycholecalciferol

Block/Question (4.6 difficulty score)
A 30-year-old woman who is at 20 weeks' gestation comes to ...
Tracheoesophageal atresia

Block/Question (4.7 difficulty score)
A 15-year-old girl is brought to the physician by her mother ...
First-degree burn

Block/Question (4.2 difficulty score)
A 16-year-old boy is brought to the physician by his father ...
Luteinizing hormone

Block/Question (7.1 difficulty score)
A 14-year-old boy is brought to the physician by his mother ...
Inhaled glue

Block/Question (5.1 difficulty score)
A 65-year-old woman undergoes surgical repair of an aneurysm ...
Area labeled with letter 'A'

Block/Question (4.8 difficulty score)
A 10-year-old girl is brought to the physician by her mother ...
Breast bud development

Block/Question (6.2 difficulty score)
A physician is sad because he has to inform a patient of ...
Yes, it is.

Block/Question (7.0 difficulty score)
A 34-year-old man is evaluated after becoming lightheaded ...
Sympathetic efferent activity: increased; parasympathetic efferent activity: decreased

Block/Question (4.9 difficulty score)
A 44-year-old woman comes to the physician for a follow-up ...
Ubiquitin ligase

Block/Question (5.0 difficulty score)
A 75-year-old man comes to the physician because of a 2-year ...
Increased hydrostatic pressure in Bowman space

Block/Question (5.8 difficulty score)
A 20-year-old man is brought to the emergency department ...
Epinephrine

Block/Question (6.5 difficulty score)
A female newborn delivered at 36 weeks' gestation is in ...
Incomplete formation of pleuroperitoneal membrane

Block/Question (6.4 difficulty score)
An 18-year-old man with Crohn disease is admitted to the ...
T-lymphocyte function

Block/Question (5.1 difficulty score)
A 4-year-old boy is brought to the physician by his parents ...
Congenital ureteral obstruction

Block/Question (3.9 difficulty score)
Ten healthy human subjects are given a new oral drug and ...
Phase 1

Block/Question (3.3 difficulty score)
A 27-year-old woman is admitted to the hospital because of a ...
Struvite

Block/Question (5.0 difficulty score)
A previously healthy 48-year-old nulligravid woman comes to ...
Endometrial hyperplasia

Block/Question (5.2 difficulty score)
An 83-year-old man is brought to the emergency department ...
Early septic shock

Block/Question (4.4 difficulty score)
A 46-year-old man is treated with oral cyclosporine after a ...
Suppressing the early response of T lymphocytes to activation

Block/Question (3.4 difficulty score)
A 54-year-old woman with hypertension and bilateral renal ...
Vasodilating prostaglandins at the afferent arteriole

Block/Question (4.2 difficulty score)
A 32-year-old woman, gravida 2, para 1, at 7 weeks' gestation ...
Ectopic pregnancy

Block/Question (6.0 difficulty score)
A 55-year-old man is admitted to the hospital for treatment ...
0.9% Saline

Block/Question (9.4 difficulty score)
A 32-year-old man comes to the physician because of a 3-month ...
Tissue: Testicle; Effect: Estradiol production

Block/Question (5.7 difficulty score)
A 45-year-old man comes to the physician because of yellow ...
Mallory hyaline

Block/Question (6.3 difficulty score)
A previously healthy 72-year-old man is brought to the ...
Gastrointestinal blood loss

Block/Question (4.0 difficulty score)
A 20-year-old man with suspected appendicitis has ...
T10

Block/Question (4.4 difficulty score)
A 45-year-old man comes to the physician because of ...
Tumor necrosis factor

Block/Question (4.8 difficulty score)
An otherwise asymptomatic 52-year-old woman comes to the ...
Failure of the ovaries to secrete 17β-estradiol

Block/Question (4.7 difficulty score)
A 16-year-old girl comes to the physician because of a 2-year ...
Dopamine β-hydroxylase

Block/Question (3.7 difficulty score)
A 41-year-old woman is evaluated because of increasingly ...
Fibromuscular dysplasia

Block/Question (3.8 difficulty score)
A 48-year-old man comes to the physician because of ...
Increased intestinal iron absorption

Block/Question (5.0 difficulty score)
A 10-year-old boy has had anemia since birth. His spleen is ...
Hereditary spherocytosis

Block/Question (2.6 difficulty score)
A 34-year-old patient with AIDS develops pulmonary TB
Macrophages

Block/Question (3.6 difficulty score)
15-year-old, lesions on neck, acid-fast bacilli, dermal infection
Temperature Sensitivity

Block/Question (3.4 difficulty score)
60-year-old man progressive shortness of breath, shipyard
Alveolar macrophage

Block/Question (2.9 difficulty score)
22-year-old woman, gravida 1, para 1... vaginal bleeding
Internal iliac

Block/Question (3.1 difficulty score)
A previously healthy 17-year-old girl is brought to the emergency
Myoglobin

Block/Question (2.5 difficulty score)
63-year-old man, 3-month history of difficulty sleeping
Increased capillary hydrostatic pressure

Block/Question (2.2 difficulty score)
14-year-old boy is brought to the emergency department 1 hour
Maxillary division of the trigeminal nerve

Block/Question (1.9 difficulty score)
50-year-old woman comes to the physician... alendronate
Inhibition of osteoclast-mediated bone resorption

Block/Question (2.1 difficulty score)
58-year-old man with supraventricular tachyarrhythmia refractory
The junction of the superior vena cava and the right atrium

Block/Question (2.9 difficulty score)
6-mercaptopurine (6-MP) is used to treat acute lymphoblastic
They must be given decreased doses of 6-MP

Block/Question (3.2 difficulty score)
An 80-year-old man with Type 2 Diabetes Mellitus is brought
Pelvic Splanchnic

Block/Question (2.6 difficulty score)
35-year-old woman has an abnormal Pap smear. Examination of these
Neoplastic cells in the sub-basement membrane connective tissue

Block/Question (4.3 difficulty score)
A 45-year-old woman comes to the physician for a follow-up
25%

Block/Question (2.9 difficulty score)
A 56-year-old woman develops a restrictive cardiomyopathy
Beta-Pleated sheet structure

Block/Question (2.5 difficulty score)
45-year-old man with poorly controlled type 2 diabetes mellitus
Enterococcus faecalis

Block/Question (2.0 difficulty score)
An 81-year-old woman is admitted to the hospital because of
Potentiates the action of antithrombin III

Block/Question (1.7 difficulty score)
18-month-old girl is brought, separation of umbilicus is delayed
Leukocyte adhesion and transmigration

Block/Question (2.6 difficulty score)
16-year-old girl comes to the physician because of a 3-day history
IgM

Block/Question (2.8 difficulty score)
A 65-year-old woman with a 20-year history of osteoarthritis
L-3 to 4

Block/Question (1.9 difficulty score)
38-year-old man with a 3-year history of type 2 diabetes mellitus
Contemplation

Block/Question (2.5 difficulty score)
27-year-old woman comes to the physician... vaginal bleeding
Trophoblastic tissue

Block/Question (2.8 difficulty score)
A new compound is taken up by bacterial cells. No energy
Carrier-mediated diffusion

Block/Question (2.8 difficulty score)
1-week-old girl is brought...defect in fatty acid oxidation
Measurement of serum acylcarnitine concentrations

Block/Question (1.9 difficulty score)
A previously healthy 3-year-old boy is diagnosed with bacterial
Interleukin-8 (IL-8)

Block/Question (2.5 difficulty score)
59-year-old comes to the physician... lack of muscle control
Cerebellum

Block/Question (1.8 difficulty score)
A 37-year-old man comes to the physician, diarrhea
Pseudomembranes of fibrin and inflammatory debris

Block/Question (2.4 difficulty score)
A 24-year-old man comes to the physician, itchy rash, camping
T-lymphocytes

Block/Question (2.9 difficulty score)
The sequence surrounding the first two exons in the human beta
Disruption of normal splicing by creation of a new 3' splice site

Block/Question (1.7 difficulty score)
A 52-year-old man is brought to the physician by a social worker
Pellagra

Block/Question (2.1 difficulty score)
A 20-year-old man comes to the physician, thirst and urinary frequ
Posterior pituitary gland

Block/Question (3.3 difficulty score)
A 30-year-old woman comes to the physician for a health maintenanc
Kidney

Block/Question (1.9 difficulty score)
35-year-old man is brought to the ED, fatigue and dizziness
Activation of adenylyl cyclase

Block/Question (3.5 difficulty score)
A female newborn is delivered at 38 weeks' gestation. Apgar scores
15 to 40

Block/Question (3.1 difficulty score)
A 27-year-old primigravid woman at 34 weeks' gestation is admitted
Schistocytes

Block/Question (1.9 difficulty score)
A 30-year-old man is brought to the ED... CT scan of the head
Middle meningeal artery

Block/Question (2.1 difficulty score)
An investigator is studying mechanisms of wound healing in a 24
Transforming growth factor-beta

Block/Question (2.6 difficulty score)
A 63-year-old man comes to the physician because of
Calcified 80% stenosis

Block/Question (2.9 difficulty score)
A 50-year-old man comes to the physician 3 days after
Calcium

Block/Question (1.5 difficulty score)
A 68-year-old man comes to the physician... erectile dysfunction
Inhibition of phosphodiesterase

Block/Question (2.0 difficulty score)
8-year-old boy is brought to the physician by his parents
Increased release of dopamine and norepinephrine

Block/Question (3.3 difficulty score)
A protein found in the brown adipose tissue of mice causes
Increased ratio of oxygen consumption to ATP generation

Block/Question (1.8 difficulty score)
A 36-year-old man undergoes elective liposuction under general
Decreases release of Ca2+ from the sarcoplasmic reticulum

Block/Question (2.2 difficulty score)
A 60-year-old man who emigrated from China to the USA
Aflatoxin

Block/Question (2.8 difficulty score)
A 29-year-old woman comes to the physician because of a 5-week
Decreased thyroid stimulating hormone, decreased free thyroxine, increased free triiodothyronine

Block/Question (2.0 difficulty score)
A 42-year-old man comes to the physician because of multiple
Development of autoantibodies against desmosomal proteins

Block/Question (2.0 difficulty score)
A 38-year-old woman comes to the physician because of a 3-day
Vagus

Block/Question (1.7 difficulty score)
A 20-year-old woman has multiple neurofibromas. Her mother...
Autosomal dominant

Block/Question (2.2 difficulty score)
A 67-year-old man has urinary urgency after placement of a urinary
Inhibition of muscarinic receptors

Block/Question (2.6 difficulty score)
A 50-year-old man who has smoked 2 packs of cigarettes a day
Increased blood HCO3-

Block/Question (1.9 difficulty score)
A 30-year-old primigravid woman at 22 weeks' gestation
Listeria monocytogenes

Block/Question (3.0 difficulty score)
A previously healthy 42-year-old man is brought to the ED
IL-1 and tumor necrosis factor (TNF)-alpha

Block/Question (3.8 difficulty score)
A 56-year-old woman comes to the physician for a follow-up exam
Maintenance of the basement membrane integrity

Block/Question (2.6 difficulty score)
In a nuclear transplantation experiment, mouse embryos are produce
Imprinting

Block/Question (2.3 difficulty score)
An 18-year-old woman develops sepsis after an abortion. Within
Decreased plasma fibrinogen concentration

Block/Question (1.6 difficulty score)
A 62-year-old woman with recurrent pulmonary emboli comes to
VII (proconvertin)

Block/Question (4.2 difficulty score)
A 19-year-old man is admitted to the hospital following a motor
Left achilles tendon

Block/Question (1.6 difficulty score)
60-year-old man comes to the physician because of a 6-month
Parietal cells

Block/Question (2.9 difficulty score)
A 42-year-old woman comes to the physician because of a 1-month
Cholesterol synthesis

Block/Question (1.7 difficulty score)
A 45-year-old woman who is intubated and mechanically
Beta-glucan carbohydrates in the cell wall

Block/Question (4.9 difficulty score)
A 58-year-old woman is brought to the emergency department
Membrane lipid peroxidation

Block/Question (2.5 difficulty score)
A 3-year-old boy with sickle cell disease has the insidious onset
Osteomyelitis

Block/Question (1.8 difficulty score)
A 59-year-old man undergoes a total thyroidectomy and central
Decreased parathyroid hormone, decreased calcium

Block/Question (1.9 difficulty score)
Ten years after total gastrectomy, a 60-year-old man
B12 (cobalamin)

Block/Question (1.7 difficulty score)
A 65-year-old woman comes to the physician because of
Lichen sclerosus

Block/Question (1.6 difficulty score)
A 28-year-old woman comes to the physician for advice on how to
Parotid gland enlargement

Block/Question (2.2 difficulty score)
A 75-year-old man comes to the emergency department because of
Salicylate poisoning

Block/Question (2.2 difficulty score)
A 55-year-old woman comes to the physician because of a 6-week
Major Depressive Disorder

Block/Question (2.2 difficulty score)
A 40-year-old woman with a 6-month history of episodic
Wegener granulomatosis

Block/Question (1.8 difficulty score)
A previously healthy 35-year-old man has become increasingly
Family history of a similar illness

Block/Question (1.8 difficulty score)
A 25-year-old woman comes to the physician because of a 6-month
Rheumatoid arthritis

Block/Question (1.8 difficulty score)
A 65-year-old man who recently emigrated from Brazil
Trypanosoma cruzi

Block/Question (2.0 difficulty score)
A 53-year-old man, who recently returned from Africa
Malaria

Block/Question (2.4 difficulty score)
A 42-year-old man comes to the emergency department because of
Infection with HIV-2

Block/Question (1.4 difficulty score)
A 70-year-old man from China has a poorly differentiated
Epstein-Barr virus

Block/Question (2.0 difficulty score)
Three days after unprotected sex with a new partner
Herpes Simplex Virus type 2

Block/Question (2.3 difficulty score)
A 27-year-old woman comes to the physician because of
Gonorrhea

Block/Question (2.4 difficulty score)
A 28-year-old man is brought to the emergency department
Dissecting aneurysm

Block/Question (2.4 difficulty score)
A newborn delivered at 38 weeks' gestation weighs 1800 g
Congenital cytomegalovirus infection

Block/Question (4.9 difficulty score)
A 70-year-old man dies in a motor vehicle collision. He had been
Tubular adenoma

Block/Question (1.7 difficulty score)
A 40-year-old woman comes to the physician because of a mole
Melanoma

Block/Question (2.6 difficulty score)
A 32-year-old man comes to the physician because of a 6-month
X-rays of the sacroiliac joints

Block/Question (1.7 difficulty score)
A 28-year-old woman, gravida 1 para 1, comes to the physician
Staphylococcus aureus

Block/Question (2.5 difficulty score)
A 60-year-old woman is brought to the physician 3-hours after the
Nephrolithiasis

Block/Question (1.7 difficulty score)
A 62-year-old man dies suddenly while playing tennis. Autopsy show
Aortic stenosis

Block/Question (1.8 difficulty score)
A 35-year-old man comes to the physician for evaluation of
Dynein arms

Block/Question (1.8 difficulty score)
A 57-year-old man with alcoholism has a distended abdomen with
Gynecomastia

Block/Question (1.9 difficulty score)
While lifting weights, a 24-year-old man develops a painful
Strangulation

Block/Question (2.0 difficulty score)
A 6-year-old boy who recently emigrated from Russia is
Vitamin E

Block/Question (1.3 difficulty score)
A 63-year-old woman is brought to the emergency department because
Delirium

Block/Question (2.0 difficulty score)
A 54-year-old woman comes to the physician 1 week after an
Myxoma

Block/Question (2.3 difficulty score)
A 48-year-old woman comes to the physician because of a 2-month
Decreased plasma renin activity

Block/Question (2.0 difficulty score)
A 70-year old man is admitted to the hospital for evaluation for
Pulmonary neoplasm

Block/Question (1.6 difficulty score)
A 27-year-old man comes to the physician for an examination
Schizoid

Block/Question (2.3 difficulty score)
A girl is brought to the physician for a well-child examination.
9

Block/Question (3.1 difficulty score)
A 55-year-old woman has left flank pain and gross hematuria
Renal cell adenocarcinoma

Block/Question (1.9 difficulty score)
A 35-year-old man comes to the physician because of a 4-day
Influenza virus

Block/Question (2.9 difficulty score)
A 60-year-old man comes to the emergency department because of the
Mesenteric venous thrombosis

Block/Question (2.0 difficulty score)
A 6-year old boy has had three systemic infections with Neisseria
Total hemolytic complement concentration

Block/Question (2.0 difficulty score)
A 62-year-old man develops a pericardial friction rub
Fibrinous pericarditis

Block/Question (3.6 difficulty score)
A 50-year-old man comes to the physician because of a persistent
Omeprazole

Block/Question (1.8 difficulty score)
A 34-year-old woman with pyelonephritis has been treated with a
Gentamicin

Block/Question (1.4 difficulty score)
A 15-year-old girl comes to the physician's office for a health
Use of sunscreen by her peers

Block/Question (1.6 difficulty score)
A 41-year-old man with asthma and an allergy to grass
Albuterol

Block/Question (2.4 difficulty score)
A 38-year-old man comes to the physician because of
Loratadine

Block/Question (1.5 difficulty score)
A 64-year-old man is brought to the emergency department 3 hours
Torsades de pointes

Block/Question (1.4 difficulty score)
A 68-year-old woman with recent onset of type 2 diabetes
Lisinopril

Block/Question (1.7 difficulty score)
A 17-year-old boy comes to the physician because of an 8kg
"Yes, your weight gain can be caused by genes and environment combined"

Block/Question (1.1 difficulty score)
A 66-year-old man with stage IV colon cancer comes to the
Loperamide

Block/Question (2.9 difficulty score)
A 62-year-old man with alcohol induced liver disease develops
Spironolactone

Block/Question (2.0 difficulty score)
A 26-year-old-woman comes to the physician 5 weeks
Sertraline

Block/Question (1.3 difficulty score)
A 60-year-old woman with a 3-year history of hyperlipidemia
Ezetimibe

Block/Question (2.1 difficulty score)
A 45-year-old woman who is a farmer is brought to the emergency
Doxycycline

Block/Question (1.2 difficulty score)
A study is designed to evaluate the efficacy of coenzyme Q10
Randomized clinical trial

Block/Question (2.3 difficulty score)
A randomized controlled study of 2000 patients with insomnia
Failure to distinguish between statistical significance and clinical significance

Block/Question (2.5 difficulty score)
In an epidemiologic study of workers in the aniline dye industry
3

Block/Question (1.2 difficulty score)
In a survey of 100 households (average three residents per
15%

Block/Question (1.2 difficulty score)
An examination is scaled so that the scores are approximately norm
67%

Block/Question (3.7 difficulty score)
A male newborn has macrocephaly with poor skull mineralization
Collagen

Block/Question (3.2 difficulty score)
A 27-year-old woman is brought to the emergency department
Inferior alveolar nerve

Block/Question (1.4 difficulty score)
A 30-year-old woman has ptosis, ophthalmoplegia, and diplopia
Thymoma

Block/Question (1.9 difficulty score)
A 45-year-old woman has a thyroidectomy because of asymmetric
Calcitonin

Block/Question (1.7 difficulty score)
A 79-year-old man is brought to the emergency department by his
Insertion of transvenous pacemaker

Block/Question (4.6 difficulty score)
An 18-year-old man has yellow nodules on the Achilles tendons
Absence of functional LDL receptors in hepatocytes

Block/Question (1.4 difficulty score)
A 68-year-old man comes to the physician because of difficulty
Left atrium

Block/Question (2.0 difficulty score)
A healthy 70-year-old woman has participated in a longitudinal stu
Residual volume: ↑; Arterial PO2: ↓; Alveolar-arterial PO2 difference: ↑

Block/Question (1.4 difficulty score)
A 20-year-old woman comes to the physician because of a 1-day hist
Mannose-binding (type I) fimbria

Block/Question (2.1 difficulty score)
A 60-year-old man comes to the physician for an examination prior
Surface kappa:surface lambda ratio

Block/Question (1.2 difficulty score)
A 6-year-old girl is brought to the physician by her mother becaus
Poxvirus

Block/Question (2.9 difficulty score)
A 69-year-old woman comes to the physician because she had weaknes
Area marked "G"

Block/Question (2.3 difficulty score)
A male newborn is born at 28 weeks' gestation. He is given ventila
Area marked "D"

Block/Question (1.1 difficulty score)
A pharmaceutical company is trying to develop a long-acting weight
Leptin

Block/Question (1.3 difficulty score)
A 68-year-old man is asked to give informed consent for a herniorr
Information, competence, voluntariness

NBME 16

Block/Question (11.2 difficulty score)
A 27-year-old man who is being treated for Hodgkin lymphoma ...
Donor T lymphocytes reacting against host cells

Block/Question (15.4 difficulty score)
An 18-month-old boy is brought to the emergency department ...
Long-chain acyl-CoA dehydrogenase

Block/Question (10.8 difficulty score)
A 38-year-old woman comes to the physician because of a ...
Serum calcium concentration

Block/Question (5.6 difficulty score)
A 24-year-old man comes to the physician because of nasal ...
α-Adrenergic agonist

Block/Question (5.1 difficulty score)
A 2-year-old boy is brought to the physician because of ...
Amino acids: decreased; Glucose: decreased; Phosphate: decreased; HCO3: decreased

Block/Question (4.4 difficulty score)
A 55-year-old man comes to the physician because of ...
Dextromethorphan

Block/Question (12.1 difficulty score)
Lesch-Nyhan syndrome, an X-linked recessive disease, is seen ...
1/50,000

Block/Question (5.4 difficulty score)
A 40-year-old woman is brought to the emergency department 1 ...
Decreased function of Na+–K+ ATPase

Block/Question (7.3 difficulty score)
An investigator is studying the regulation of pulmonary ...
Intravenous infusion of 0.9% saline for 5 minutes

Block/Question (4.6 difficulty score)
A screening program is instituted for detection of vaginal ...
10%

Block/Question (6.0 difficulty score)
A 79-year-old woman is admitted to the hospital after ...
Go for a long walk outside daily

Block/Question (6.2 difficulty score)
A 16-year-old boy is brought to the emergency department 30 ...
Area labeled by the letter 'E'

Block/Question (6.6 difficulty score)
A 5-year-old boy is brought to the emergency department ...
Cerebral edema

Block/Question (6.5 difficulty score)
A 54-year-old man has an aneurysm in the distal portion of ...
2.4

Block/Question (4.5 difficulty score)
A 28-year-old woman comes to the physician because of a ...
Ureter

Block/Question (10.4 difficulty score)
An 18-year-old man with acute lymphoblastic leukemia comes to ...
Amphotericin B

Block/Question (3.8 difficulty score)
A 55-year-old woman comes to the physician because of a ...
Parathyroid hormone: decreased; 1,25-Dihydroxycholecalciferol: increased

Block/Question (3.3 difficulty score)
A 24-year-old African American man comes to the physician ...
Pseudofolliculitis barbae

Block/Question (10.9 difficulty score)
A 12-year-old boy is brought to the physician because of a ...
Abnormal myelin sheaths

Block/Question (7.6 difficulty score)
During an experiment, the concentration of glycolytic ...
Glyceraldehyde-3-phosphate dehydrogenase

Block/Question (3.9 difficulty score)
A 48-year-old woman comes to the physician because of a ...
Increased follicle-stimulating hormone

Block/Question (6.0 difficulty score)
A 5-year-old boy is brought to the physician because of an ...
Lysosomes

Block/Question (13.5 difficulty score)
An animal study is conducted to assess the effects of smoking ...
Mucus production and secretion: increased; Activity of airway cilia: decreased; Alveolar macrophage function: decreased

Block/Question (9.4 difficulty score)
An 85-year-old woman is diagnosed with a fracture of the ...
Morphine is metabolized to active metabolites that accumulate

Block/Question (5.3 difficulty score)
A 33-year-old man comes to the physician because of a 3-month ...
Glycogen phosphorylase

Block/Question (4.7 difficulty score)
During an experimental study of oxygen consumption in the ...
Proximal tubule

Block/Question (9.2 difficulty score)
A 35-year-old man comes to the physician because of a 3-year ...
Adenylyl cyclase

Block/Question (9.8 difficulty score)
A 20-year-old man is brought to the physician because of a ...
Induction of cytochrome P450 enzymes that activate acetaminophen to a hepatotoxic metabolite

Block/Question (3.9 difficulty score)
An 83-year-old man comes to the physician because of a 3-day ...
Bullous pemphigoid antigen

Block/Question (3.7 difficulty score)
A 45-year-old man is admitted to the hospital because of ...
Iron

Block/Question (4.6 difficulty score)
A 15-year-old girl is brought to the emergency department 12 ...
Increased absorption of calcium in the gastrointestinal tract

Block/Question (4.9 difficulty score)
A 53-year-old homeless man with alcoholism is brought to the ...
Normal oral flora

Block/Question (4.0 difficulty score)
An 18-year-old woman comes to the physician because of ...
Interstitial nephritis

Block/Question (4.6 difficulty score)
A Gram stain is performed on a sputum specimen. Pink rods and ...
Outer membrane

Block/Question (5.0 difficulty score)
An investigator is studying strains of Streptococcus ...
Natural transformation

Block/Question (4.1 difficulty score)
An 8-year-old girl is brought to the physician for a ...
“Your daughter’s development is normal.”

Block/Question (4.5 difficulty score)
A 27-year-old nulligravid woman comes to the physician ...
Clomiphene

Block/Question (4.1 difficulty score)
A study is designed to evaluate the relationship between ...
Cross-sectional

Block/Question (4.1 difficulty score)
A 54-year-old woman who works as a nurse comes to the ...
Interferon gamma

Block/Question (4.9 difficulty score)
A 65-year-old woman comes to the physician because of a ...
Pulmonary small cell carcinoma metastatic to the brain

Block/Question (4.2 difficulty score)
A 68-year-old man comes to the physician because of a 2-hour ...
Right ophthalmic

Block/Question (3.3 difficulty score)
A 27-year-old woman comes to the physician because she is ...
Reassurance

Block/Question (6.1 difficulty score)
A female newborn is delivered at term to a 35-year-old ...
Enlarged thyroid gland

Block/Question (3.4 difficulty score)
A 70-year-old man comes to the physician because of ...
Schedule regular appointments to monitor the patient

Block/Question (4.2 difficulty score)
A 25-year-old woman comes to the physician because of a ...
Fasting insulin: increased; Testosterone: increased; Luteinizing hormone: increased

Block/Question (4.7 difficulty score)
A 10-year-old girl has fatigue and appears pale. Her father ...
Deficiency of erythrocyte spectrin

Block/Question (3.7 difficulty score)
A 24-year-old woman comes to the physician for a follow-up ...
Tuberous sclerosis

Block/Question (6.8 difficulty score)
A 78-year-old man comes to the physician because of fever, ...
Bacterial endocarditis

Block/Question (5.5 difficulty score)
A 39-year-old woman with rheumatoid arthritis comes to the ...
Tumor necrosis factor-α

Block/Question (9.1 difficulty score)
A 35-year-old man comes to the physician because of a 6-month ...
Gastrin

Block/Question (5.1 difficulty score)
A 42-year-old woman undergoes biopsy of suspicious ...
High-grade, low-stage neoplasm

Block/Question (3.3 difficulty score)
A previously healthy 18-year-old man is brought to the ...
Brief psychotic disorder

Block/Question (7.9 difficulty score)
A 70-year-old woman is found to have persistent fever despite ...
Candida albicans

Block/Question (7.8 difficulty score)
A 43-year-old woman comes to the physician because of ...
Degeneration of motoneurons of the lumbar cord

Block/Question (12.5 difficulty score)
A 51-year-old woman comes to the physician because of a ...
Area labeled by the letter 'B'

Block/Question (11.2 difficulty score)
A 32-year-old man begins to laugh while eating dinner with ...
While swallowing: closed; Immediately after laryngeal irritation: closed; while coughing: open

Block/Question (5.3 difficulty score)
A new antiplatelet agent is developed for the prevention of ...
8%

Block/Question (5.1 difficulty score)
A 42-year-old woman is brought to the emergency department 30 ...
Posterior communicating

Block/Question (10.2 difficulty score)
A 32-year-old woman, gravida 4, para 0, aborta 3, delivers a ...
Unbalanced chromosome rearrangement

Block/Question (3.3 difficulty score)
A 40-year-old woman comes to the emergency department because ...
Entamoeba histolytica

Block/Question (6.0 difficulty score)
A 35-year-old woman participates in a study of a new ...
Day 12

Block/Question (3.0 difficulty score)
A full-term female newborn develops respiratory distress ...
Congenital diaphragmatic hernia

Block/Question (2.9 difficulty score)
A previously healthy 52-year-old man is brought to the ...
Binding of antibody to the acetylcholine receptor

Block/Question (4.7 difficulty score)
A 54-year-old woman is admitted to the hospital with an acute ...
Grade 4/6, holosystolic murmur heard best over the lower left sternal border and the cardiac apex

Block/Question (4.7 difficulty score)
A 40-year-old woman comes to the physician for an initial ...
Antagonizes VLDL-cholesterol secretion

Block/Question (3.4 difficulty score)
A 55-year-old woman comes to the physician because of a ...
Parathyroid hormone: down; 1,25-Dihydroxycholecalciferol: up

Block/Question (4.9 difficulty score)
A 39-year-old woman with type 1 diabetes mellitus comes to ...
Stimulation of hepatic glucose production

Block/Question (2.8 difficulty score)
A 15-year-old boy is brought to the physician for an ...
Fibrillin

Block/Question (4.4 difficulty score)
A newborn female is diagnosed with hypothyroidism 2 days ...
Thyroxine (T4)

Block/Question (2.0 difficulty score)
A 48-year-old man is referred for evaluation of possible
Increase in width

Block/Question (2.2 difficulty score)
A 57-year-old man comes to the physician because of a 6-month
Inferior mesenteric

Block/Question (2.5 difficulty score)
A 66-year-old man has a surgical excision of a brain mass
Kidney

Block/Question (3.3 difficulty score)
Poliovirus mRNA lacks a 5' m7G cap but is translated efficiently
Presence of an internal ribosome entry site

Block/Question (2.5 difficulty score)
A 30-year-old woman with Li-Fraumeni syndrome is found to have
Impaired regulation of apoptosis

Block/Question (1.8 difficulty score)
A 30-year-old man develops hemoptysis, dyspnea, weakness, and
Autoantibodies against host basement cell membrane

Block/Question (1.8 difficulty score)
A 53-year-old man is brought to the emergency department 1 hour
Microglial cells

Block/Question (1.9 difficulty score)
A 43-year-old man comes to the physician because of a
Rotundum

Block/Question (2.2 difficulty score)
A 50-year-old man comes to the physician because of a progressive
Collagen

Block/Question (1.7 difficulty score)
A 7-year-old girl is brought to the emergency department 30 minute
Right lower

Block/Question (1.8 difficulty score)
A 16-year-old girl with cystic fibrosis is brought to the
Vitamin E

Block/Question (2.0 difficulty score)
A 1-year-old boy is brought to the physician for a well-child
Inability to produce melanin

Block/Question (2.3 difficulty score)
A 25-year-old man comes to the physician 8 hours after the onset
Rupture of an intervertebral disc

Block/Question (1.6 difficulty score)
A 62-year-old man with unstable angina pectoris undergoes coronary
Left coronary

Block/Question (1.6 difficulty score)
A 36-year-old man comes to the physician because of a 2-hour
Activation of antithrombin III

Block/Question (1.6 difficulty score)
A 1400-g (3-lb 2-oz) female newborn is delivered to a 33-year-old
Cyclooxygenase

Block/Question (2.4 difficulty score)
A healthy 24-year-old woman participates in a study to determine
"B" point on the graph

Block/Question (1.3 difficulty score)
A 31-year-old woman is diagnosed with invasive squamous
T lymphocytes

Block/Question (1.2 difficulty score)
A 29-year-old woman comes to the physician for advice on losing
Follicular atrophy

Block/Question (1.9 difficulty score)
A male newborn delivered at 28 weeks' gestation is tachypneic and
Decreased numbers of lamellar bodies

Block/Question (1.5 difficulty score)
A 56-year-old woman has frequently burned herself while cooking
Syrinx of the central region of the spinal cord from C-4 to T-5

Block/Question (1.7 difficulty score)
A 5-year-old boy with mental retardation is grossly obese and has
Maternal origin of both chromosomes 15

Block/Question (1.5 difficulty score)
A 64-year-old man with a 25-year history of alcoholism is brought
Killing of bacteria in the gut that generate ammonia

Block/Question (2.5 difficulty score)
A 2-year-old boy is brought to the physician because of
Heteroplasmy

Block/Question (1.3 difficulty score)
A 54-year-old man is scheduled for physical therapy 3 days
Lateral (external) rotation

Block/Question (1.4 difficulty score)
A previously healthy 59-year-old man comes to the emergency
DNA polymerase

Block/Question (1.6 difficulty score)
A 26-month-old boy is brought to the physician because of a 3-day
Nocardia asteroides

Block/Question (1.6 difficulty score)
A 51-year-old man who is a farmer comes to the physician
Leukemoid reaction

Block/Question (2.4 difficulty score)
A 50-year-old man comes to the emergency department because of
NADPH oxidase

Block/Question (1.1 difficulty score)
An 80-year-old woman who develops fever and cloudy urine 4 days
Pseudomonas aeruginosa

Block/Question (1.2 difficulty score)
A 66-year-old man is brought to the emergency department 30 minute
Increasing cGMP

Block/Question (2.2 difficulty score)
Two sets of patients (Groups X and Y) of similar age, weight
Blood:gas partition coefficient

Block/Question (0.9 difficulty score)
A 62-year-old man comes to the physician for a follow-up
Contemplation

Block/Question (1.9 difficulty score)
A 56-year-old man is scheduled for repair of an inguinal
Ligamentum flavum

Block/Question (2.5 difficulty score)
An otherwise healthy 60-year-old man comes to the physician
Scattered shrunken cells

Block/Question (1.8 difficulty score)
A 28-year-old woman, gravida 2, para 1, comes to the physician
Venous hypertension

Block/Question (2.0 difficulty score)
On three separate occasions, a 25-year-old man is given an
Partial agonist at angiotensin II receptors

Block/Question (1.2 difficulty score)
A 35-year-old man with a longstanding history of chronic atrophic
Parietal

Block/Question (1.7 difficulty score)
An increase in the amount of iron inside cultured hepatocytes lead
Translation of ferritin mRNA

Block/Question (2.8 difficulty score)
A 35-year-old woman is given 500 mg of drug X intravenously.
8

Block/Question (1.4 difficulty score)
A 30-year-old woman comes to the physician because of a 1-week
Oligodendrocytes

Block/Question (1.7 difficulty score)
A 55-year-old man comes to the physician because of a 3-day
Volume depletion

Block/Question (2.7 difficulty score)
A 3-year-old boy is brought to the physician by his parents
Feces-contaminated soil

Block/Question (2.4 difficulty score)
A 23-year-old man comes to the physician because of difficulty
Pudendal nerves

Block/Question (1.7 difficulty score)
Two days after undergoing a right hip replacement operation
Dead space

Block/Question (2.3 difficulty score)
A 9-month-old boy is brought to the emergency department by his
Ectodermal neural crest cells

Block/Question (2.4 difficulty score)
A 22-year-old man comes to the physician because of infertility.
46,XXY

Block/Question (1.5 difficulty score)
A 49-year-old woman with breast cancer develops increased numbness
Microtubules for axonal transport

Block/Question (1.3 difficulty score)
A 6-month-old girl is brought to the physician by her mother
Facial

Block/Question (2.2 difficulty score)
A 64-year-old man is evaluated for cough, dyspnea, and chest pain
Hyponatremia

Block/Question (2.5 difficulty score)
A 76-year-old man with a 1-month history of a pulsatile
Anomalous origins of multiple renal arteries to each kidney

Block/Question (1.4 difficulty score)
A healthy 25-year-old man lives at 10,000 feet above sea level
Hematocrit

Block/Question (1.5 difficulty score)
A 62-year-old man with chronic renal disease comes to
Plasma hemoglobin concentration

Block/Question (2.2 difficulty score)
A 46-year-old man comes to the physician because of a 6-month
Neuronal degeneration

Block/Question (1.5 difficulty score)
A 65-year-old man with peripheral vascular disease comes to the
Jejunum

Block/Question (1.7 difficulty score)
Two days after admission to the hospital because of sickle
Renal papillary necrosis

Block/Question (2.5 difficulty score)
A 24-year-old woman was stung on her right thumb by a bee 30
Influx of macrophages producing interleukin-1 (IL-1), IL-6, and tumor necrosis factor-alpha

Block/Question (0.7 difficulty score)
A 62-year-old woman with recurrent non-small cell carcinoma
Tubulin

Block/Question (1.2 difficulty score)
A 42-year-old man with hepatitis C undergoes a liver biopsy
Chronic inflammation

Block/Question (1.4 difficulty score)
A 43-year-old woman who has been diagnosed with immune thrombo
"B" label on the CT

Block/Question (1.2 difficulty score)
A 65-year-old woman with hypertension comes to the emergency
Labetalol

Block/Question (2.0 difficulty score)
A 9-year-old boy is brought to the physician by his mother
Protein structure

Block/Question (1.1 difficulty score)
A previously healthy 7-year-old boy is brought to the physician by
Bartonella henselae

Block/Question (2.5 difficulty score)
A couple seeks genetic counseling because of a family history
0%

Block/Question (3.9 difficulty score)
A 60-year-old man with no history of bleeding problems has
Kallikrein formation

Block/Question (1.1 difficulty score)
An investigator is conducting a study of antiretroviral agents
Enfuvirtide

Block/Question (1.9 difficulty score)
An investigator is studying bacterial virulence factors
Transcription

Block/Question (1.6 difficulty score)
A 3-year-old boy is brought to the emergency department by
Procollagen synthesis

Block/Question (2.2 difficulty score)
The chemotherapy regimen prescribed for a 55-year-old
Ventricular cardiac muscle fibers

Block/Question (1.7 difficulty score)
A 6-month-old boy with a history of recurrent upper and lower
T-lymphocyte deficiency

Block/Question (1.9 difficulty score)
An investigator is conducting a study of Plasmodium infection in
P. vivax and P. ovale

Block/Question (2.4 difficulty score)
A 68-year-old woman comes to the physician because of a 1-year
Superior mesenteric

Block/Question (1.6 difficulty score)
A 23-year-old woman, who was diagnosed with Sjorgen
Substance P

Block/Question (1.2 difficulty score)
A 66-year-old man comes to the physician because of a 6-month
Dilated cardiomyopathy

Block/Question (2.2 difficulty score)
A 56-year-old man with a palpable hard nodule on the prostate
Pelvic parasympathetic nerves

Block/Question (1.4 difficulty score)
A 52-year-old man comes to the physician because of a 3-week
Fasting serum glucose concentration

Block/Question (1.6 difficulty score)
A 70-year-old African American woman comes to the physician 1 day
Gender

Block/Question (0.8 difficulty score)
A 20-year-old woman who works as a secretary comes to
Migraine

Block/Question (0.9 difficulty score)
A 60-year-old man comes to the physician for a routine health
Aortic valve stenosis

Block/Question (1.3 difficulty score)
A 35-year-old woman comes to the physician because of intermittent
Pericarditis

Block/Question (1.8 difficulty score)
A 38-year-old woman comes to the physician for a pre-employment
Iron deficiency anemia

Block/Question (1.3 difficulty score)
A 28-year-old woman comes to the physician because of a 1-week
Wegener granulomatosis

Block/Question (1.5 difficulty score)
A 67-year-old man comes to the physician because of a 2-month
Cigarette smoking

Block/Question (2.3 difficulty score)
A 76-year-old man comes to the physician for a follow-up exam
Drinking home-distilled liquor

Block/Question (1.2 difficulty score)
A pale 62-year-old man has increasing fatigue and indigestion
Hairy cell leukemia

Block/Question (1.3 difficulty score)
A 4-month-old boy is brought to the physician because of recurrent
Chediak-Higashi syndrome

Block/Question (1.2 difficulty score)
A 62-year-old man comes to the physician because of pain in the
Prostate

Block/Question (1.4 difficulty score)
A 16-year-old girl is brought to the emergency department by
Eclampsia

Block/Question (1.2 difficulty score)
A 75-year-old woman with osteopenia comes to the physician for a
Normal aging

Block/Question (2.5 difficulty score)
A 51-year-old man with a 3-month history of hepatitis B antigen-
Segmental ischemic necrosis

Block/Question (1.1 difficulty score)
A 19-year-old man who plays college basketball comes to the
Myxoma

Block/Question (1.7 difficulty score)
A 12-year-old girl is brought to the physician by her father
Dermatomyositis

Block/Question (1.9 difficulty score)
A 55-year-old woman develops a headache, temperatures to 40
Streptococcus pneumoniae

Block/Question (1.4 difficulty score)
A 25-year-old man is brought to the emergency department because
Peutz-Jeghers

Block/Question (1.1 difficulty score)
A previously healthy 27-year-old woman comes to the physician
Costochondritis

Block/Question (0.8 difficulty score)
A 26-year-old man undergoes colonoscopy because of
Ulcerative colitis

Block/Question (1.1 difficulty score)
A 35-year-old man is referred for psychiatric evaluation by
Dysthymic disorder

Block/Question (1.8 difficulty score)
A 69-year-old African American woman has moderate hypertension and
Irbesartan

Block/Question (1.6 difficulty score)
A 58-year-old African American man with congestive heart failure
Sildenafil

Block/Question (1.1 difficulty score)
A 27-year-old man with acute myelocytic leukemia recieves
Mesna

Block/Question (1.5 difficulty score)
A 38-year-old woman undergoes laparoscopic cholecystectomy
Ondansetron

Block/Question (1.5 difficulty score)
A 12-year-old girl who recently immigrated to the USA
Praziquantel

Block/Question (2.3 difficulty score)
A 6-week-old boy is brought to the physician for a follow-up
Streptococcus pneumoniae

Block/Question (1.0 difficulty score)
A 51-year-old woman receives the diagnosis of pheochromocytoma
Phenoxybenzamine

Block/Question (2.4 difficulty score)
A 70-year-old woman is brought to the emergency department by her
Cimetidine

Block/Question (1.7 difficulty score)
A 15-year-old Native American boy is brought to the emergency
Physostigmine

Block/Question (0.9 difficulty score)
A 5-year-old girl is brought to the physician by her mother
Ethosuximide

Block/Question (1.4 difficulty score)
A 19-year-old woman is brought to the physician by
Risperidone

Block/Question (2.3 difficulty score)
A 67-year-old woman comes to the physician for a health
Low sensitivity

Block/Question (1.8 difficulty score)
A case-control study is conducted to explore a possible
Biased measurement of the exposure

Block/Question (2.2 difficulty score)
A study is conducted to assess 32 patients in a community
31

Block/Question (1.4 difficulty score)
To determine whether children of workers in a lead foundry
First-graders whose parents had never worked at the foundry

NBME 15

Block/Question (9.9 difficulty score)
A 7-year-old boy is brought to the physician because of a ...
Virion release

Block/Question (8.6 difficulty score)
A healthy 3-year-old boy has a cleft lip and palate. He has ...
Multifactorial

Block/Question (8.0 difficulty score)
Which of the following best explains why deoxygenated blood ...
Deoxyhemoglobin is a better buffer of hydrogen ions than oxyhemoglobin

Block/Question (4.5 difficulty score)
A 9-year-old boy has mild mental retardation and a 4-year ...
Tuberous sclerosis

Block/Question (4.2 difficulty score)
A 48-year-old woman comes to the emergency department because ...
Increased cardiac parasympathetic activity

Block/Question (3.6 difficulty score)
A 65-year-old man with a history of ischemic heart disease ...
33%

Block/Question (6.5 difficulty score)
A 3-year-old girl is brought to the physician because of a ...
Interferon-gamma receptor

Block/Question (5.1 difficulty score)
A 4-day-old male newborn who was born at home is brought to ...
First

Block/Question (5.4 difficulty score)
A 75-year-old woman is brought to the physician because of a ...
Releases NF-κB after undergoing phosphorylation

Block/Question (3.5 difficulty score)
One-half hour after an uncomplicated vaginal delivery, a ...
Oxytocin

Block/Question (4.4 difficulty score)
A 36-year-old man who is heterozygous for an LDL-receptor ...
LDL receptor

Block/Question (3.3 difficulty score)
A 23-year-old woman comes to the physician because of a 3-day ...
Oculomotor nerve

Block/Question (5.1 difficulty score)
An investigator is designing a study to compare a new ...
Stratification

Block/Question (5.1 difficulty score)
A 59-year-old man comes to the physician because of a 10-day ...
Imatinib

Block/Question (5.2 difficulty score)
A 6-year-old boy with severe mental retardation and ...
0.2 to 0.5

Block/Question (3.0 difficulty score)
A 22-year-old man is brought to the emergency department 30 ...
Deep fibular (peroneal)

Block/Question (4.4 difficulty score)
A 23-year-old woman comes to the physician because of a ...
Glucokinase

Block/Question (7.3 difficulty score)
A healthy 25-year-old man participates in a study of muscle ...
epp Amplitude: 1; mepp Amplitude: 1; Response to Ach: 1

Block/Question (7.2 difficulty score)
A 2-year-old girl is brought to the emergency department 20 ...
Atropine

Block/Question (2.9 difficulty score)
A 32-year-old man comes to the physician for his annual ...
Schizoid personality disorder

Block/Question (7.5 difficulty score)
A 56-year-old woman comes to the physician because of a ...
Helicobacter pylori

Block/Question (6.1 difficulty score)
A 67-year-old man is brought to the physician because of a ...
Aneurysm of the posterior communicating artery

Block/Question (3.8 difficulty score)
A previously healthy 48-year-old man is brought to the ...
Degenerating epithelial cells and dirty brown granular casts

Block/Question (5.2 difficulty score)
A 25-year-old woman with a history of rheumatic fever and ...
Streptococcus mitis

Block/Question (5.6 difficulty score)
A 64-year-old man comes to the physician because of a 2-month ...
Increased fibrosis in the interstitium

Block/Question (3.3 difficulty score)
A 30-year-old man is brought to the physician by his wife ...
Porphobilinogen deaminase

Block/Question (6.7 difficulty score)
A 43-year-old woman comes to the physician because of a ...
Complex partial

Block/Question (4.2 difficulty score)
A 22-year-old woman is found to be HIV positive after sexual ...
Protein processing

Block/Question (4.4 difficulty score)
A previous healthy 26-year-old woman comes to the physician ...
Area labeled by letter 'E'

Block/Question (9.2 difficulty score)
A 47-year-old man is admitted to the hospital for treatment ...
Increased pulmonary capillary pressure

Block/Question (5.5 difficulty score)
A 35-year-old woman, gravida 1, para 1, comes to the ...
Nicotinic acetylcholine receptor

Block/Question (7.3 difficulty score)
A 2-month-old male infant is brought to the emergency ...
Glycine receptor

Block/Question (4.7 difficulty score)
A 24-year-old woman with Marfan syndrome comes to the ...
Hypervolemia

Block/Question (3.1 difficulty score)
A 25-year-old primigravid woman at 25 weeks' gestation comes ...
Prematurity

Block/Question (6.0 difficulty score)
A 72-year-old woman is admitted to the hospital because of an ...
Left coronary, circumflex, posterior interventricular (posterior descending)

Block/Question (7.1 difficulty score)
A 43-year-old man with a 10-year history of alcoholism comes ...
Decreased glutathione

Block/Question (4.9 difficulty score)
A 4-year-old boy is brought to the physician by his father ...
Cytoskeleton

Block/Question (2.9 difficulty score)
A 45-year-old man comes to the physician for an initial ...
Mitral regurgitation

Block/Question (5.2 difficulty score)
A 37-year-old woman is brought to the emergency department ...
Cardiogenic

Block/Question (7.8 difficulty score)
A 3-year-old girl is brought to the physician because of a ...
Abnormal targeting of these enzymes to lysosomes

Block/Question (5.5 difficulty score)
A 75-year-old man with chronic obstructive pulmonary disease ...
C5a

Block/Question (4.4 difficulty score)
A study was begun in the 1950s to determine the causes of ...
Cohort study

Block/Question (3.9 difficulty score)
A 56-year-old woman is brought to the emergency department by ...
Lipopolysaccharide

Block/Question (4.6 difficulty score)
A 50-year-old man comes to the physician for a routine health ...
Medullary

Block/Question (4.3 difficulty score)
A 1-year-old boy is brought to the physician by his parents ...
RNA splice error

Block/Question (5.0 difficulty score)
A newborn undergoes surgical repair of esophageal atresia. ...
Endoderm

Block/Question (4.4 difficulty score)
A 5-year-old boy is stung on his foot by a bee. Within 30 ...
Gap formation between endothelial cells

Block/Question (5.7 difficulty score)
A 65-year-old man with hypertension volunteers to participate ...
Acid-base: Metabolic alkalosis; Volume contraction: yes

Block/Question (4.9 difficulty score)
A 27-year-old man comes to the physician because of a 3-hour ...
Prolonged fecal excretion of the organism

Block/Question (4.1 difficulty score)
A 28-year-old African American man comes to the physician ...
Ethnicity

Block/Question (6.7 difficulty score)
A 13-year-old boy is scheduled to receive chemotherapy for a ...
T-lymphocyte thymocytes localized to the thymic cortex

Block/Question (5.1 difficulty score)
A 2-month-old girl is brought to the physician for a ...
Congenital neutropenia

Block/Question (3.1 difficulty score)
A 42-year-old woman with multiple sclerosis is brought to the ...
Medial longitudinal fasciculus

Block/Question (3.9 difficulty score)
An 18-year-old man is brought to the physician by his father ...
Inquiry about a history of anabolic steroid use

Block/Question (3.9 difficulty score)
A 30-year-old woman has had Hodgkin disease that was ...
Therapy for Hodgkin disease causes mutations in hematopoietic stem cells, and one mutant cell progresses to leukemia

Block/Question (3.3 difficulty score)
A 2-month-old boy is brought to the physician because of ...
Peroxisomes

Block/Question (4.3 difficulty score)
A paper says, "We chose the sample size to have an 80% power ...
5%, Type I error

Block/Question (2.6 difficulty score)
A 51-year-old man with a 5-year history of Wegener ...
Hematuria

Block/Question (3.8 difficulty score)
A male newborn is delivered at term with a right-sided aortic ...
Third and fourth branchial pouches

Block/Question (3.6 difficulty score)
A 17-year-old boy with chronic renal insufficiency undergoes ...
Hydronephrosis

Block/Question (4.2 difficulty score)
A newborn delivered at 28 weeks' gestation is in severe ...
Lung elastic recoil

Block/Question (4.8 difficulty score)
A 40-year-old woman with breast cancer is brought to the ...
Occipital lobe

Block/Question (3.7 difficulty score)
A 45-year-old man comes to the physician for a follow-up ...
Venous return: decreased; Carotid sinus baroreceptor activity: decreased; Cerebral blood flow: decreased

Block/Question (4.0 difficulty score)
A previously healthy 18-year-old woman comes to the physician ...
β-Lactamase production

Block/Question (4.6 difficulty score)
A 52-year-old man is brought to the physician 3 days after ...
No constriction because the retinal ganglion cells in the left eye have been destroyed

Block/Question (3.8 difficulty score)
A couple has two children with osteogenesis imperfecta type ...
Germline mosaicism

Block/Question (4.4 difficulty score)
A 65-year-old woman comes to the physician for a follow-up ...
Osteoblast activity: decreased; Osteoclast activity: increased; RANKL: increased

Block/Question (5.4 difficulty score)
A 45-year-old woman (III,7) comes to the physician for a ...
Incomplete penetrance

Block/Question (4.3 difficulty score)
A 25-year-old woman comes to the physician because of ...
Nuclear/retinoid X binding to DNA

Block/Question (3.2 difficulty score)
A 70-year-old woman is found dead in her bed in a skilled ...
Hypertrophy

Block/Question (5.0 difficulty score)
During a series of normal skeletal muscle twitches, the ATP ...
ATP is quickly regenerated from creatine phosphate

Block/Question (3.7 difficulty score)
A 25-year-old woman comes to the physician because of general ...
Thrombocytopenia

Block/Question (4.8 difficulty score)
An 18-month-old boy with severe combined immunodeficiency ...
Irradiated packed red blood cells

Block/Question (5.4 difficulty score)
A 4-year-old boy with a karyotype of 47,XY+21 develops ...
Excess lymphoblasts

Block/Question (4.0 difficulty score)
A 72-year-old woman comes to the physician because of diffuse ...
Osteomalacia

Block/Question (2.8 difficulty score)
A 31-year-old woman is treated for Plasmodium vivax malaria ...
Primaquine kills hypnozoites

Block/Question (4.2 difficulty score)
A study is conducted to evaluate the effectiveness of cough ...
Lack of blinding between groups

Block/Question (4.6 difficulty score)
An investigator is studying Helicobacter pylori strains ...
Slipped-strand mispairing

Block/Question (2.9 difficulty score)
A previously healthy 26-year-old woman comes to the physician ...
External hemorrhoid

Block/Question (2.3 difficulty score)
A 22-year-old man comes to the physician because of an 8-year hist
Decreased conjugation of bilirubin

Block/Question (2.6 difficulty score)
A 72-year-old man comes to the physician because of a 3-month hist
Protrusion of the fundus into the chest above the level of T10

Block/Question (1.5 difficulty score)
A 1-month old male newborn is brought to the physician for a well-
Number of Melanocytes = Normal, Melanosomes = ↓

Block/Question (3.0 difficulty score)
A 50-year-old man comes to the emergency department because of a 2
Anemia

Block/Question (2.3 difficulty score)
Following a stroke, a 68-year-old man has a language problem. His
H (Wernicke's area)

Block/Question (2.6 difficulty score)
Influenza virus strains are characterized by differing sensitivity
HA

Block/Question (1.6 difficulty score)
An investigator conducts a study of the molecular basis of von
Proteasome

Block/Question (1.5 difficulty score)
A 50-year-old man underwent a bowel resection for colon cancer
Hematogenous spread of colonic tumor via the portal venous system

Block/Question (2.4 difficulty score)
A 6-year-old girl is brought to the physician for a follow-up exam
Glutamine

Block/Question (1.0 difficulty score)
A 38-year-old man is admitted to the hospital after sustaining
Vitamin K deficiency caused by depletion of the normal gut flora

Block/Question (1.2 difficulty score)
A 24-year-old man develops recurrent vesicular lesions on his uppe
Sensory neurons

Block/Question (2.0 difficulty score)
A 20-year-old woman comes to the physician because her menstrual p
The neural plate is present, but the neural tube is not yet complete

Block/Question (2.0 difficulty score)
A 30-year-old nulligravid woman comes to the physician because
Estrogen in adipose tissue

Block/Question (1.4 difficulty score)
A 23-year-old nulligravid woman comes to the physician because she
Blockage of both fallopian tubes

Block/Question (2.2 difficulty score)
A 50-year-old man comes to the physician because of a 2-week histo
Stenosis of the right coronary artery

Block/Question (1.2 difficulty score)
A 43-year-old woman is admitted to the hospital 40 minutes
Hippocampus

Block/Question (1.2 difficulty score)
A 45-year-old man with an ulcer in the anterior superior portion
Diaphragm

Block/Question (1.2 difficulty score)
A previously healthy 25-year-old woman comes to the physician for
Germ cells

Block/Question (1.1 difficulty score)
The vaccine against diphtheria confers protective immunity
Purified inactivated toxin

Block/Question (1.0 difficulty score)
A 3-year-old girl is brought to the physician because of fever and
Dynein

Block/Question (1.1 difficulty score)
A 22-year-old man comes to the emergency department 30 minutes
Median

Block/Question (1.5 difficulty score)
A 70-year-old man has a 4-month history of weight loss, abdominal
Pancreatic enzymes

Block/Question (1.4 difficulty score)
A 50-year-old man is brought to the physician because of progressi
"D" label in the image

Block/Question (1.3 difficulty score)
A 60-year-old man is brought to the emergency department
Reversible, dose-dependent

Block/Question (1.2 difficulty score)
A 32-year-old man is brought to the emergency department in a coma
pH 7.28, PO2(mmHg) 50, PCO2(mmHg) 60, HCO3-(mEq/L) 27

Block/Question (0.9 difficulty score)
A 54-year-old woman comes to the physician because of a 2-week his
This patient's medication has an agonist effect on endometrial estrogen receptors

Block/Question (1.0 difficulty score)
A 45-year-old man with chronic renal failure is admitted
25-hydroxycholecalciferol

Block/Question (1.0 difficulty score)
A 66-year-old woman with ovarian cancer comes to the emergency dep
Increased tubular hydrostatic pressure

Block/Question (1.3 difficulty score)
An 82-year-old woman with alcohol dependence is admitted to the
Inadequate hydroxylation of collagen polypeptides

Block/Question (1.3 difficulty score)
A 60-year-old woman develops a secreting adenoma of the
Calcium concentration in feces

Block/Question (1.5 difficulty score)
A 2-month old male infant with a ventricular septal defect is brou
Left ventricular pressure increased, right ventricular pressure decreased, left atrial pressure decreased

Block/Question (0.9 difficulty score)
A 13-year-old girl is brought to the physician by her mother
Transcription

Block/Question (0.9 difficulty score)
A 23-year-old primigravid woman develops fever and chills 2 days
Listeria monocytogenes

Block/Question (1.4 difficulty score)
A male newborn has multiple congenital anomalies resulting from
Absence of adrenal medulla

Block/Question (1.0 difficulty score)
The lymphoproliferative properties of the gammaherpesviruses
Nasopharyngeal carcinoma

Block/Question (1.3 difficulty score)
A 30-year-old woman comes to the physician because of a 6-month hi
Serotonin

Block/Question (1.5 difficulty score)
A 3-year-old boy with chronic otitis media is scheduled to undergo
Low blood solubility

Block/Question (1.4 difficulty score)
A previously healthy 35-year-old woman develops hypoxemia 35 min
PO2 50, PCO2 80, (A-a)O2 10

Block/Question (1.5 difficulty score)
A 45-year-old man has a 2-day history of severe abdominal pain
Action of pancreatic enzymes on adipose

Block/Question (0.9 difficulty score)
During an experiment of muscle contraction, intracellular calcium
Myosin bonding sites on actin remain covered by troponin C

Block/Question (0.6 difficulty score)
A 14-year-old boy has fatigue, intermittent right lower
Vitamin B12 (cobalmin)

Block/Question (1.0 difficulty score)
A 21-year-old woman at 30 weeks' gestation is admitted to the hos
Cyclooxygenase

Block/Question (1.5 difficulty score)
A 56-year-old woman is brought to the emergency department because
1000

Block/Question (1.1 difficulty score)
A 32-year-old woman comes to the physician because of a 6-month
Collecting duct

Block/Question (1.1 difficulty score)
A 48-year-old woman comes to the physician because of a 2-month
Autoantibody (IgM) reactive with IgG

Block/Question (1.2 difficulty score)
A 32-year-old woman comes to the physician for a follow-up exam
Internal iliac

Block/Question (1.0 difficulty score)
A 53-year-old man develops a fever and hypotension while being
Clostridium perfringens

Block/Question (0.9 difficulty score)
A 4-year-old boy has respiratory tract colonization with Pseudomon
Autosomal recessive

Block/Question (1.1 difficulty score)
A previously healthy 27-year-old woman is brought to the emergency
Superantigen activation of T lymphocytes

Block/Question (1.0 difficulty score)
A 50-year-old woman comes to the physician because of progressive
Endothelin

Block/Question (1.8 difficulty score)
A 55-year-old man comes to the physician because of a 2-month hist
Motor fibers from the vagus nerve

Block/Question (1.1 difficulty score)
An 18-year-old man comes to the physician because of 1-year
Prolactin

Block/Question (1.0 difficulty score)
A 69-year-old woman is brought to the physician by her son because
Normal pressure hydrocephalus

Block/Question (0.9 difficulty score)
A 7-month-old girl is brought to the physician for a well-child ex
Coarctation of the aorta

Block/Question (1.0 difficulty score)
A 71-year-old woman is brought to the emergency department 1 hour
Temporal arteritis

Block/Question (1.0 difficulty score)
A 10-year-old girl with sickle cell disease is brought to the
Salmonella

Block/Question (0.9 difficulty score)
A 62-year-old woman comes to the physician because of a 3-week
Multiple myeloma

Block/Question (1.6 difficulty score)
A 75-year-old woman comes to the physician because of 3-month hist
Lentigo maligna

Block/Question (1.3 difficulty score)
A 27-year-old woman comes to the physician because of 1-month
Dilated cardiomyopathy

Block/Question (1.4 difficulty score)
A 72-year-old man with poorly controlled hypertension is brought t
Decreased femoral pulses

Block/Question (1.2 difficulty score)
A 17-year-old boy comes to the physician because of a 4-month hist
Tuberculosis abscess of the spine

Block/Question (1.3 difficulty score)
A food handler has a fresh furuncle on his face. He prepares
Vomiting

Block/Question (1.2 difficulty score)
A 15-year-old is brought to the physician because of right wrist
Avascular necrosis of the proximal scaphoid bone

Block/Question (1.8 difficulty score)
An investigator who wishes to test the hypothesis that a number
Immunohistochemistry

Block/Question (1.6 difficulty score)
A 67-year-old man comes to the physician because of a 2-month
Burning

Block/Question (1.5 difficulty score)
A 54-year-old man comes to the physician because of increasing
Major depressive disorder

Block/Question (1.0 difficulty score)
A 23-year-old woman is brought to the emergency department by her
Heroin

Block/Question (1.2 difficulty score)
A 43-year-old man comes to the physician because of progressive
Inherited protease deficiency

Block/Question (0.9 difficulty score)
An 8-year-old boy with moderate mental retardation is brought
Prader-Willi syndrome

Block/Question (1.2 difficulty score)
A 3-year-old girl is brought to the physician because of a 1-month
Thyroid follicles

Block/Question (1.2 difficulty score)
A 25-year-old primigravid woman at 12 weeks' gestation comes to th
Partial hyatidiform mole

Block/Question (1.2 difficulty score)
A 42-year-old woman comes to the physician for an exam
Beta-thalassemia minor

Block/Question (1.2 difficulty score)
A 19-year-old woman is brought to the physician by her parents
Olanzapine

Block/Question (1.1 difficulty score)
A 51-year-old woman undergoes dilation and curettage for dysfuncti
Succinylcholine

Block/Question (1.4 difficulty score)
A 35-year-old metal worker collapses after exposure to an unknown
Amyl nitrite

Block/Question (1.4 difficulty score)
A 69-year-old man with benign prostatic hyperplasia develops
Bethanechol

Block/Question (1.2 difficulty score)
A 34-year-old woman who is a scientist is brought to the
Potassium iodide

Block/Question (1.0 difficulty score)
A 19-year-old woman comes to the physician for a follow-up examina
Doxycycline

Block/Question (1.0 difficulty score)
A study is conducted to assess a new prenatal test for Down syndro
99%

Block/Question (1.1 difficulty score)
A study is conducted of patients with restrictive airway disease
Increased body fat is associated with lower lung capacity

Block/Question (1.2 difficulty score)
Vision screening is performed on 4000 people who are older than 65
Unable to calculate due to insufficient data

Block/Question (1.0 difficulty score)
An 18-year-old woman is brought to the emergency department 2 hour
Bleeding time

Block/Question (1.0 difficulty score)
A 28-year-old woman is brought to the hospital by her boyfriend be
Determine the C-peptide concentration in the latest blood specimen drawn

Block/Question (1.4 difficulty score)
A 32-year-old man has a 3-month history of episodic epigastric
Decreased smoking

Block/Question (0.8 difficulty score)
A 55 year old woman with colon cancer and a healthy ..
Apoptosis

Block/Question (0.3 difficulty score)
A 26 year old woman comes to the physician because of vaginal irri
oral metronidazole

Block/Question (0.3 difficulty score)
a 4-year-old boy with asthma is brought to the emergency departmen
Binding to its cytoplasmic receptor, translocation to the nucleus, and activation of transcription of target genes

Block/Question (0.2 difficulty score)
A 24-year-old woman is admitted to the hospital because of acute p
Ectopic pregnancy

NBME 13

Block/Question (20.1 difficulty score)
A 77-year-old woman dies in the hospital after a long ...
Interleukin-1 (IL-1)

Block/Question (6.5 difficulty score)
An 18-month-old boy is brought to the physician because of ...
Iduronate sulfatase

Block/Question (5.7 difficulty score)
A 22-year-old woman comes to the physician 3 months after she ...
Anterior to the sternocleidomastoid muscle

Block/Question (4.6 difficulty score)
A 3-year-old girl is found to have a grade 4/6, loud, harsh, ...
Ventricular septal defect

Block/Question (4.5 difficulty score)
A 32-year-old woman comes to the physician because of a ...
Myasthenia gravis

Block/Question (4.4 difficulty score)
A 4-year-old boy is brought to the emergency department ...
Reaction step labeled by the letter 'E'

Block/Question (3.4 difficulty score)
A 12-year-old African American girl is brought to the ...
Polymerization of hemoglobin with hypoxic conditions due to amino acid substitution in the β chain

Block/Question (3.3 difficulty score)
A 43-year-old woman with metastatic colon cancer has ...
The agent being a humanized antibody

Block/Question (4.3 difficulty score)
A 43-year-old man comes to the physician for a routine health ...
Low-calorie

Block/Question (3.8 difficulty score)
A 20-year-old man has cramping periumbilical pain. After ...
Interleukin-1 (IL-1)

Block/Question (3.2 difficulty score)
An 18-year-old man has had temperatures to 38.3°C (101°F), a ...
T lymphocytes

Block/Question (3.4 difficulty score)
A male newborn at 34 weeks' gestation is delivered vaginally. ...
Endothelium

Block/Question (3.3 difficulty score)
A 15-year-old boy is brought to the physician by his mother ...
Type I (immediate) hypersensitivity

Block/Question (3.5 difficulty score)
A female newborn is delivered at 34 weeks' gestation in an ...
Nitric oxide

Block/Question (2.9 difficulty score)
A 5-month-old boy is brought to the physician because of a ...
Thyroglossal duct

Block/Question (2.8 difficulty score)
In order to determine risk factors for death from coronary ...
Observational cohort study

Block/Question (2.9 difficulty score)
A 36-year-old man who is seropositive for HIV has had a ...
Pneumocystis jiroveci (formerly P. carinii)

Block/Question (3.3 difficulty score)
A 47-year-old woman comes to the physician because she wants ...
Activation of nuclear gene transcription

Block/Question (5.2 difficulty score)
A 5-year-old boy is brought to the physician by his mother ...
Ischium

Block/Question (2.9 difficulty score)
A 23-year-old woman comes to the physician because of a ...
Dextromethorphan

Block/Question (3.4 difficulty score)
A 54-year-old man has a squamous cell carcinoma of the right ...
Loss of heterozygosity

Block/Question (3.7 difficulty score)
A previously healthy 42-year-old Asian woman is brought to ...
Induction of cytochrome P450

Block/Question (3.5 difficulty score)
Homologous pairing of chromosomes in prophase I is essential ...
Crossing over

Block/Question (4.9 difficulty score)
A 32-year-old woman comes to the physician because she has ...
Clomiphene

Block/Question (3.2 difficulty score)
A 31-year-old woman is brought to the emergency department by ...
Desensitization of nicotinic receptors

Block/Question (3.1 difficulty score)
A previously healthy 40-year-old man is brought to the ...
Increased protein degradation

Block/Question (4.3 difficulty score)
A 33-year-old woman who is right-handed is brought to the ...
Voltage-gated Na+ channels

Block/Question (4.6 difficulty score)
A study is conducted to evaluate the onset and course of ...
Population-based

Block/Question (5.2 difficulty score)
An autopsy is done on a 46-year-old woman who died of ...
Paraganglioma

Block/Question (3.2 difficulty score)
A cluster of three cases of nosocomial pneumonia caused by a ...
Promote thorough hand cleansing before and after medical personnel visit each patient

Block/Question (3.2 difficulty score)
A 23-year-old woman with type 1 diabetes mellitus is brought ...
Inability to produce hydroxy-halide radicals

Block/Question (2.7 difficulty score)
A 25-year-old woman undergoes a radical mastectomy with ...
Compression sleeve

Block/Question (3.7 difficulty score)
A young adult couple has been unable to conceive for the past ...
Seminal vesicles

Block/Question (3.8 difficulty score)
A 25-year-old man with cystic fibrosis comes to the physician ...
Biofilm formation in the lower respiratory tract

Block/Question (3.5 difficulty score)
An 18-year-old woman with mild mental retardation is brought ...
Apo B

Block/Question (7.0 difficulty score)
A mouse melanoma, B-16, is highly metastatic. A clone of the ...
Homing

Block/Question (3.1 difficulty score)
A 22-year-old woman comes to the physician for a follow-up ...
Antiphospholipid antibody syndrome

Block/Question (6.7 difficulty score)
A previously healthy 32-year-old man is brought to the ...
Alcohol dehydrogenase

Block/Question (3.6 difficulty score)
A 40-year-old woman is brought to the emergency department 30 ...
Vascular malformation

Block/Question (3.3 difficulty score)
A 33-year-old woman comes to the physician because of a 16-kg ...
Cortical hyperplasia

Block/Question (3.1 difficulty score)
A 55-year-old man with hepatic encephalopathy is brought to ...
Lactulose

Block/Question (3.3 difficulty score)
A previously healthy 25-year-old man is admitted to the ...
Alveolar hyaline membrane

Block/Question (3.6 difficulty score)
A 64-year-old woman comes to the physician because of a ...
Esophageal peristalsis: decreased; Lower esophageal sphincter tone: decreased

Block/Question (3.8 difficulty score)
A 62-year-old man is brought to the emergency department ...
Pulmonary edema