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Azithromycin is a macrolide, not an aminoglycoside FYI, and its use in HIV is primarily as prophylaxis at very low CD4 counts for, among other things, the mycobacterium avium complex.
How would we have known to choose Zidovudine over Lamivudine tho
@nbmehelp the sketchy with Princess Izolde (Zidovudine) eating bone marrow was my only tip off
you have ero bone marrow if you take idovudine
the z's were supposed to be bold idk what happened.
you have Zero bone marrow if you take Zidovudine
So probenecid is the best answer here because they only specified acetylsalicylic acid, not the dosage, and low-dose acetylsalicylic acid has the opposite effect.
Another reason not to use TCAs (or alprazolam or haloperidol for that matter) is that the Beers criteria state to avoid the use of all of those drugs in patients over the age of 65.
What is the clue that this is not pulmonary fibrosis? How do I decide between Doxorubicin and Bleomycin?
Also both bleomycin and methotrexate cause pulmonary fibrosis, so that helped me rule both those out and focus on the HF instead of the pulmonary symptoms
The S3 gallop and enlarged heart together are very strong evidence for heart failure. It's much more likely for heart failure to cause interstitial edema than for pulmonary fibrosis to directly cause heart failure.
You are not crazy. I got this question wrong for the same reason but here's why I think NBME was going with fibrates. You can use the Friedewald equation to calculate LDL cholesterol from the values they give. This equation is LDL= Total Cholesterol-HDL Cholesterol-(Triglycerides/5). The Triglycerides/5 term is an estimate for VLDL. If you calculate it in this case you get an LDL of 120 which is firmly normal and thus the patient would ostensibly not benefit from statin therapy.
omg when the hell am I going to remember this equation? Jesuusssssss, this kind of details makes me want to give up on STEP