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Comments ...

 +1  (nbme24#50)
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hWy nto iicllanc ralit? Tyhe culdo trepor a arre vresade fcetfe ni aspeh 4 alnlcici lrita g?ithr

sunshinesweetheart  there's no control group. it's just a case study. x3 +2
sunshinesweetheart  plus clinical trials at that stage would have had tons and tons of participants (and, most importantly to rule out all the answers, control group) +
servage  I totally thought it was phase 4 of a clinical trial as part of post-market surveillance. Smh. +
loaloagubba  For phase 4 they report to the said findinds and adverse to the FDA via a portal not to a journal. +




Subcomments ...

submitted by haliburton(214),
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sThi si ewrat xnioiiatctno. pnht:u.hv//w7twbo5cwie8dn7ni/mb91s./m.l.gp7

thisisfine   Agreed! It's along the lines of those marathon runners who collapse questions. Nothing but water for 24 hours = getting rid of too much sodium. +1  
temmy  are we just going to ignore the diarrhea for 3 days? what is its significance +4  
kard  Temmy, We aint Ignoring the Diarrhea, Actually the most likely electrolytes to get lost with it is sodium> chloride> potassium> bicarbonate... Plus the Water intoxication -> HYPONATREMIA +1  
bronchophony  why not hypoglycemia? +1  
saulgoodman  Because glucose is not an electrolyte, it does not conduct electricity in solution. The question is asking "Which of the following electrolyte abnormalities". +4  


submitted by sweetmed(144),
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bronchophony  Why not complement activation? +1  
joyceeepan  the way i though about it was: you need antibodies (IgG/IgM) to activate the complement system. But there's no such a thing as an anti-gout antibody. (and it is not an infection neither) +1  
an_improved_me  Thats not exactly true for a couple reasons. I saw a UWorld question that said something along the lines of an ApoProtein being useful b/c it binds the urate crystals, and makes it less likely for the crystals to be opsinized/recognized by neutrophils. Therefore, Abs do play a role. Secondly, you can have activation of coplement via the alternative pathway, which does not require ABs. +