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aren't retinal cells a type of somatic cell? Why not is the mutation not considered in the somatic cell of the child?
Although this mutation would be considered somatic, I believe the question is just asking you to be specific as to which cells. If you answered "somatic cells of the child," that's quite broad and could apply to almost anything.
There is a Uworld qx that explain this in detail> ID: 863
I read the answer options too fast so got this wrong. It is a somatic cell type, but somatic in general implies a higher risk for developing other cancers. The hint here is that the physician stated he is unlikely to develop any other neoplasms, so it is a specific double hit mutation in the retina.
wouldn't she have any possibility of developing osteosarcoma as well? :(
did some reading and it seems like osteosarcoma only occurs in familial retinoblastoma with RB mutation