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 +0  (nbme18#35)

I believe this man has cachexia (from his hx of cancer)--which is mainly due to increased proinflammatory cytokines

santal  Weight loss, muscle atrophy and fatigue that occur in chronic disease (eg AIDS, heart failure, COPD) -- > Cachexia. Mediated by TNF alpha, IFN gamma, IL-1 and IL-6 (These stimulate the ubiquitin proteasome pathway to degrade skeletal muscle proteins) Courtesy: FA 2019 Pg. 228 + uworld

 +0  (nbme18#37)

Berylliosis, Hypersensitivity pneumonitis and Sarcoidosis all have granuloma formation. Also eliminated cryptogenic organizing pneumonia b/c the pt didn't have any chronic diseases/meds. So, I was left with Idiopathic pulmonary fibrosis as the choice.

pathogen7  Also "fibroblastic foci" is a big buzzword for IPF, I believe.




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