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 +0  (nbme21#8)

So I must have misunderstood - the arcuate arteries are in the cortex which is why I picked cortex - but we're saying the renin will always be highest in the cortex? - p. 564 FA

Subcomments ...

submitted by hayayah(884),

Cysteine-cysteine chemokine receptor 5 (CCR5) is a protein found on the surface of CD4 cells.

yotsubato  Note, this is NOT in FA +  
sbryant6  It is in UWorld. +2  
almondbreeze  it's in FA2019 pg.110 +1  
almondbreeze  but missing the full name for CCR5 +4  
demihesmisome  CXCR4 is also a chemokine receptor. +  

submitted by hayayah(884),

HELLP syndrome: Hemolysis Elevated Liver enzymes Low Platelets.

A manifestation of severe preeclampsia. Blood smear shows schistocytes. Can lead to DIC and hepatic subcapsular hematomas Ž rupture Ž severe hypotension.

mambaforstep  FA 2019 pg 629 +1  
qball  One thing I find odd with this question is HELLP is a manifestation of severe preeclampsia but she has had an otherwise unremarkable pregnancy. Shouldn't she have hypertension/edema in regards to her pregnancy beforehand? +  
demihesmisome  Pre-eclampsia, if not severe, can be entirely asymptomatic. +1  

submitted by apurva(19),

The real thing is TSH, T3, T4 and thyroglobulin cannot cross placenta. TRH, Iodine, TSI can cross. If mother has high TSH (considering primary hypothyroidism) —> Poor brain development If mother has TSI (Hashimoto) —> cross the placental barrier —Increase in thyroid gland (May present with stridor at birth.

demihesmisome  Ahhhhh Thank you. This was what I was trying to understand. +  
apurva  please note that free t4 can cross the placenta +1  

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