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 +0  (nbme21#43)
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sI thsi sujt nd-mrea dyesmrno? ectiD r acetls-ml nlaneatuogdir aduces yb and.ocayi.vcn..nm olas onemrp?hi

drschmoctor  Yes, this is red man syndrome. Mast-cell degranulation directly due to Vancomycin: +

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submitted by yotsubato(968),
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nI lbogoyi, hapse vtnioaria si a tmdeho fro ligaden ihwt yiaplrd niavygr moetrisennvn wutthoi quneirigr madnor o.ntimtua tI svloneiv the iovinraat of eirtnop n,pxeseiros neequfltry in an n-ffoo hniof,as itihnw etrdneffi tsrpa of a ebtrlacia uptlapi.oon As shcu eth pnpohyete acn wctsih ta funieqerces ttah ear hmcu erhigh toemsisme( ;gt)&1% atnh lsaslccia otnutmai taers. Pehsa oairaivtn ertncotbsui to eecuvrnil by eragientgn hnteeot.eryeig luhgAhot ti ash eenb smot onmmcoly sueitdd ni hte ttenxco of eimmnu ,oveisna ti si oesbderv ni myan ehort aarse as wlle nda si dleepmoy by vsrioau pstey of itbcreaa, nldgcniiu Snamalelol scesp.ei


whoissaad  is it the same thing as antigenic variation? +8  
dorsomedial_nucleus  No, antigenic variation involves genomic rearrangement Phase variation can be thought of as MORE or LESS of something. An on/off switch. No DNA is being rearranged, just under or overexpressed in response to the environment. +4  
makinallkindzofgainz  This isn't in Zanki, Lightyear, or First Aid, and I don't remember ever learning about this in class. Thanks NBME! :D +18  
jurrutia  You wouldn't expect the difference in phenotype of a given organism in a given patient to change because of mutations. It has to be something other than mutation. Phase variation is the only option that sounded like non-mutation. +