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Comments ...

 +0  (nbme24#10)

hope this helps everyone, even the ones that just "like" everything

 +1  (nbme24#17)

so, the Key words that no one is mentioning : communicating hydrocephalus

the pathophys goes like this :

an inflammatory setting (i.e., subarachnoid hemorrhage) yield fibrosis / scarring of the arachnoid granulations => impaired CSF drainage

the key points / concepts they are trying to test here : 1. do you know what communicating hydrocephalus (without them telling you those words) 2. do you know what's the pathophysiology (of communicating hydrocephalus) is ?

 +0  (nbme22#32)

Wallerian Degeneration : axonal degeneration distal to site of transection + proximal axonal retraction

Axotomy (axonal tran-section) of peripheral nerves results in, Schwann cells : a. breaking down myelin into small fragments and englufs it b. recruiting macrophages to dispose of axonal debri c. producing growth factors to promote regeneration of axons

 +0  (nbme22#43)

Posterior cord Lesions are called: Radial Plus Palsy.

Cuz Posterior cord has BOTH Radial Nerve & Axillary nerve & cuz they are the 2 terminal branches that come off the posterior cord, so Sx include: triceps & wrist weakness, limitations finger extension indicate injury to radial nerve is located above innervation of triceps Injury of radial nerve occurs in axilla / above weakness of wrist, finger extension Axillary N. injury : weakness of abduction (paralysis of deltoid muscle), sensory shoulder loss. Axillary nerve also innervate teres minor muscle.

Hope this helps

 +0  (nbme22#28)

Hemochromatosis (Auto Recessive HFE Gene on Ch.6) Labs :

↑↑ Serum Iron & Ferritin & Transferrin saturation


 +0  (nbme22#3)

Injection = ONLY IgG
Vs Oral = IgG & IgA

Cholera is transmitted via GI (oral) route , so you'd need the IgA protection, since it's mostly IgA that protects from GIT pathogens

 +0  (nbme22#1)

i kinda of feel "odd" asking this question : but the patient had an MI 6 months ago, so why would it be unlikely that he was told to "restrict salt, restrict fluids (water) " ??

Guess what i'm asking is : what makes choice E such an unlikely choice (JVD, bi-basilar crackles, peripheral edema) ?

& @meningitis : his bp is 135/82 mmHg ... why is that "HIGH" ??

Subcomments ...

submitted by keycompany(111),

Image shows Crescent Sign, a common finding in Abdominal Aortic Aneurysms due to mural thrombus occlusion.

happysingh  crescent sign is a finding on radiographs that is associated with avascular necrosis, NOT aneurysms !!! what you're seeing is Calcification of wall of the aortic aneurysm +  

submitted by whoissaad(10),

Artery of ductus deferens is a branch of infeior vesical artery. So why is B wrong?

happysingh  the question is asking about "adequate arterial supply" +  

Some other endocrine like cells and disorders for reference:

  1. Salt-and-pepper chromatin (fine granular cytoplasm) in Endocrine tumors:

  2. Medullary thyroid carcinoma

  3. neuroendocrine tumors and pheochromocytoma
  4. Carcinoid Tumor (serotonin) --- (also has sheets of uniform cells)
  5. Small Cell Carcinoma of lungs = Small, blue cells with scant cytoplasm and granular chromatin) = flat, oval-shaped cells with scant cytoplasm and hyperchromatic nuclei

  6. Small Blue Cells

  7. Ewing sarcoma (anaplastic malignant tumor)
  8. SCC of lungs
  9. flat, oval-shaped cells with scant cytoplasm and hyperchromatic nuclei
happysingh  i've never heard of " 6. Small Blue Cells" cancer / tumor / carcinoma .... +1  
niboonsh  might want to look at fa pg 665 +  

Good fact to commit to memory: you lose bicarb in the stool (hence why diarrhea causes nonanion gap metabolic acidosis), and especially lose potassium with laxative abuse (as mentioned in the question stem).

sbryant6  I'm going to go take a big bicarbonate poop now. +4  
happysingh  i would suggest that you look into it a bit more. Why ? Had an nbme question (which confused the shit out of me) cuz, Bluemic Pt. who was abusing Laxatives (had the up & down arrows) and this is what it gave : Laxative Abuse — Metabolic Alkalosis :   ↓K+     ↑Cl-                   ↑pH    ↓HCO3- so one of the points of distinction IS the increase in Cl- with laxative abuse (vs. vomiting, which was a knee-jerk reaction when i hear bulimia) +