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Then why the choice D, “Inability of leukocytes to ingest microorganisms“, is incorrect？Moreover, Staphylococcus aureus is not an intracellular microorganism. Thank you for your help!
Because in CGD, the macrophages are capable of taking in bacteria but aren't able to do the oxidative burst required to actually kill them. So the macrophages just house live bacteria which leads to granulomas full of walled-off but not dead bacteria. And S. aureus isn't intracellular as part of its normal life cycle, but being eaten by a macrophage isn't part of its normal life cycle. Whether an organism gets eaten by a macrophage isn't part of the consideration of whether it's intracellular.
Ilioingual covers part of the medial thigh, base of penis and anterior scrotum
Posterior scrotal nerves are a branch of pudendal and cover said area
Doral nerves cover the dorsum of the penis which are also from the pudendal
I thought it was the Genitofemoral nerve because the genital branch supplies the cremaster and scrotal skin, but I looked it up and: The genital branch passes through the *deep inguinal ring* and enters the inguinal canal; also, Ilioinguinal wraps around the spermatic cord just like the question stem says.
"The structures which pass through the canals differ between males and females:
in males: the spermatic cord and its coverings + the ilioinguinal nerve." from wiki "Inguinal canal", which means the ilioinguinal nerve lies on the external surface of spermatic cord. https://en.wikipedia.org/wiki/Inguinal_canal
The contents of spermatic cord includes, "nerve to cremaster (genital branch of the genitofemoral nerve) and testicular nerves (sympathetic nerves). It is worth noting that the ilio-inguinal nerve is not actually located inside the spermatic cord, but runs along the outside of it, in the inguinal canal." from wiki spermatic cord.
Exactly!! it's an autosomal dominate disease!
Autosomal dominant diseases are variably expressive. Still, I think this was a badly written question (should have given us some family history).
Also, FA says that fractures may occur during the birthing process, which is what I believe they were going for. I don't believe these findings would be seen at birth with any of the other choices.
Yeah I thought I outsmarted NBME by selecting Rickets bc it said no family history ... guess I got played lol.
Could it be a sporadic cases? Spontaneous Mutation
This is a change in a gene that occurs without an obvious cause, in a family where there is no history of the particular gene mutation. OI is inherited as an autosomal dominant trait. Approximately 35% of cases have no family history and are called "sporadic" cases. In sporadic cases, OI is believed to result from a spontaneous new mutation.
That's so infuriating I stared at this question for 20 minutes thinking I did something wrong
lol..my math never worked either. I also just chose the closest number. also, screw this question author for doing that.
this is why you never waste 7 minutes on a question.... because of shit like this
Why the FUCK did they not just give us a clearance of 0.1 if they're going to fuckin round it anyways...
in ur maths, why did u put 24h/1day and not 1day/24h? if the given Cl was 0.09L/hr/kg. I know it just is a math question, but i´d appreciate if someone could explain it.
LMAO games NBME plays
magic math!!!!! how TF r we supposed to know when they round and when they don't like wtf im so pissed someone please tell me step isn't like this...with such precise decimal answers and a calculator fxn you would assume they wanted an actual answer!
OMG, I've got the 25.92 mg/kg/day, which isn't any of the answer choices listed. So I chose the D 51.8, because 51.8 is double of 25.9......I thought I must have make a mistake during the calculation ......
They purposely did that so if you made a mistake with your conversion like I did, you might end up with 2.5 which was one of the answer choices. SMH
I did well, but I thought that my mistake was something to do with the conversion and end up choosing 2.5 because it is similar to 25.92