to snoo-finity ... and beyond!
Welcome to joha961's page.
Contributor score: 30
So do we just have to memorize this...
@yotsubato Not necessarily. I can't remember a formula to save my life. The Css is the amount you want in the blood. The clearance is the fraction removed per unit time. Since we want to maintain a steady state, we only need to replace what is removed.
Thus, maintenance dose = amount present * fraction removed.
Same question. How could you determine between the specific nerve roots (C7 vs. C8)?
Someone I was talking to (and post below) was saying that first aid mentions triceps is C7, so that's what should've been the big thing for us.
From a random paper I found, “Arguably p53’s most important function is to act as a transcription factor that directly regulates perhaps several hundred of the cell’s RNA polymerase II (RNAP II)-transcribed genes.” So normally it increases RNA pol binding; a mutation would decrease it.
The TATA box is part of the promoter region site where RNA polymerase II and other transcription factors bind to DNA. A defect would therefore decrease binding of RNA polymerase.
Also you can reason it out (I got this wrong because you have to be really meticulous) since we know that loss of p53 = cancer. Cancer = want more cell division = don’t want inhibitory gene = less transcription of said gene.