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Welcome to kaf’s page.
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Comments ...

 +0  (nbme15#39)

also interferon beta is clue she has MS.





Subcomments ...

submitted by ergogenic22(303),
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bbr  Isn't is just motor symptoms, thats why its Partial? Maybe Im conflating things here. But complex partial decoded would be: Complex (lose consciousness) and partial (just 1 area of the brain, just motor). +6  
euchromatin69  simple seizure wont have altered cociousness....alt. concious = complex or generaliised +  
i_hate_it_here  What's the difference between a complex partial and an absence seizure? +  
kaf  Absence - they just gaze off as if they're daydreaming. +1  


submitted by cassdawg(957),

I don't like this question for many reasons, but basically he has sarcoidosis (noncaseating granulomas with no pathogen found on biopsy) which according to First Aid is more common in African-American females. Since he is African-American that is his risk factor (FA2020 p676).

cheesetouch  FA2018 p658 +  
i_hate_it_here  Questions like this let me know that the ideals of racism have never left the medical system. Ok, so he's "African-American", is he of actual African descent? Is sarcoidosis just increased in american found black people, or is it black people of African descent, what about Jamaican? Afro-Latino, Europeans?? I hate that they teach us things like this and we're suppose to take it at face value. +1  
kaf  agree...medicine is full of racism, sexism and so on. Some meds work differently and diseases present differently etc...for ex., ACE inhibs in AA vs white...or MI presentation in women vs men. +  


submitted by cassdawg(957),

The -navirs are protease inhibitors, so a mutation in protein processing would cause resistance.

radzio1  in FA p203 it literally says Protease Inhibitors act by inhibiting maturation and assembly. So thats what I picked. Why is protein processing more appropriate? +2  
radzio1  in FA p203 it literally says Protease Inhibitors act by inhibiting maturation and assembly. So thats what I picked. Why is protein processing more appropriate? +  
kaf  maybe packaging means sending out of the cell? +  
pakimd  on pg 203 of first aid it says protease inhibitors inhibit HIV-1 protease which cleaves polypeptide products of HIV mRNA into their functional parts; proteases are responsible for cleaving and processing proteins made from HIV RNA transcript into functional parts and protease inhibits this process by inhibiting proteases responsible for processing proteins that are made from HIV mRNA +  
pakimd  on pg 203 of first aid it says protease inhibitors inhibit HIV-1 protease which cleaves polypeptide products of HIV mRNA into their functional parts; proteases are responsible for cleaving and processing proteins made from HIV RNA transcript into functional parts and protease inhibits this process by inhibiting proteases responsible for processing proteins that are made from HIV mRNA +  
pakimd  protease inhibitors* inhibit proteases +  
pakimd  and then those functional proteins are assembled and packaged into virions to be released and infect other T cells +  
pakimd  if you look at the illustration on pg 201 of FA youll see that they say that protease inhibitors inhibit proteolytic processing +1  
cheesetouch  in a UW question I did, it said that protease inhibitors inhibit gag-pol cleavage, which would probably be considered a form of processing. gag -> p24 capsid and p17 matrix proteins pol -> reverse txase, aspartate protease, integrase pakimd makes a great point above about the img on 201. I think this is just kind of a crappy question LOL +  
whk123  [Check here the image says that, sketchy pharma mentioned regarding pol gene too in regard of navirs] (https://basicmedicalkey.com/wp-content/uploads/2017/02/image01621.jpeg) => Here it comes +