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 +1  (nbme20#19)

This patient presents with a mitochondrial myopathy since the disorder is inherited from the mother. Mitochondrial myopathies show “ragged red fibers” on muscle biopsy due to the accumulation of diseased mitochondria in the subsarcolemma of the muscle fiber.

katsu  Mitochondrial myopathies—rare disorders; often present with myopathy, lactic acidosis, and CNS disease, eg, MELAS syndrome (mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes). 2° to failure in oxidative phosphorylation. Muscle biopsy often shows “ragged red fibers” (due to accumulation of diseased mitochondria).

 +0  (nbme20#17)

Schizoid personality disorder is characterized by voluntary social withdrawal, limited emotional expression and social isolation.

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