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 +2  (nbme21#18)

In bullous pemphigoid, autoantibodies are made against BPAg1 and BPAg2 found on hemidesmosomes.

 +10  (nbme21#28)

Mixed venous oxygen tension is the amount of oxygen bound to hemoglobin as it returns to the right side of the heart after traveling to the tissues.

Decreased oxygen delivery to the tissues due to decreased cardiac output leads to the tissues extracting more oxygen from the passing RBCs than they normally would, which decreases the overall mixed venous oxygen tension.

pparalpha  A helpful equation is CO=rate of O2 consumption/(arterial O2 content-venous O2 content): Fick principle If CO is decreased, then the difference between arterial O2 content and venous O2 content is increased

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