to snoo-finity ... and beyond!
Welcome to pparalpha's page.
Contributor score: 23
Glygocen stores are depleted within 24h. This person has signs and symptoms of longterm nutritional deficiences.
Atypical lymphocytes are CD8+ T cells, not CD4+. Remember that.
According to Sketchy and Amboss: dextromethorphan is a weak opioid receptor AGONIST and NMDA receptor ANTAGONIST (it's not an agonist).
Li-Fraunemi syndrome = SBLA (sarcoma, breast, leukemia, adrenal gland syndrome) and occurs because of an autosomal dominant inherited mutation of p53
APC: linked to FAP (colorectal cancer)
RET: linked to papillary thyroid cancer, MEN 2A, MEN 2B
The thing that threw me off was that the only connection in her FH to the above SBLA reference was the mention of a paternal cousin with adrenocortical carcinoma. The other two mentioned had brain cancers, which seem completely outside the scope of the above mnemonic. Then again, as mentioned elsewhere, I suppose the best policy on these is just to rule out the absolute wrong answers.
I swear, the NBME is lying when they tell us to choose the "best" answer on some of these. What they actually mean in practice is for us to choose the least shitty.
^ this guy cracked the code. nbme ur doomed.
@privatejoker: I feel the pain. Quick FYI: UW includes brain in the associated tumors.
we can just make her thing SBBLA and hopefully never get this wrong again
@privatejoker: according to UW, Li Fraumeni includes SABBB(sarcoma/adrenocortical/breast/brain/blood(leukemia))
Thanks! Good mnemonic
A helpful equation is CO=rate of O2 consumption/(arterial O2 content-venous O2 content): Fick principle
If CO is decreased, then the difference between arterial O2 content and venous O2 content is increased
Hyotension will lead to decreased arterial pressure and DECREASED stretch. This leads to decreased afferent barcreceptor firing (carotid sinus and aortic arch). This leads to an increase in efferent sympathetic firing and decreased efferent PNS stimulation. This leads to vasoconstriction, increased HR and increased BP.
The way I remember this, carotid massage slows the heart. So baroreceptor stimulation (more impulses) increases parasympathetic output.
FA 2018 pg 291 has helpful image/description