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Welcome to staygoodpupper’s page.
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submitted by medstudied(1),
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acn oenosme xpainle woh mnhreiop is gearddde itno actevi otmeeibtlsa thta cmaacu?etul I oudtnc'l nidf nay scorues htat ttase this s'tIn ti miozleebdta horgtuh het 05P4 ysstme and reextdce ni er?inu

staygoodpupper  Morphine mostly undergoes phase II metabolism and is then excreted renally. Some of the metabolites are metabolically active, and her creatinine was a little elevated, so renal clearance could have been impaired. +10  
celedkin the diagram in this article is useful to follow the metabolism of morphine +1  

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pug_sheen  I think they are talking about the GHRH receptor on somatotrophs, which works through the cAMP pathway. +  
staygoodpupper  I don’t know how it relates to GH/IGF-1 in particular, but the question said there was a mutation in the alpha subunit of Gs, which activates adenylyl cyclase. +3  
kash1f  I agree the patient does have Acromegaly, but in the question it talked about how the patient had a mutation that prevented the GTPase activity of Gas. So Gs would be overactive --> excess adenylyl cyclase +27  
hyperfukus  ugh i was so excited too bc i thought i remembered jak stat epicfail +3