to snoo-finity ... and beyond!
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in the question stem, they are asking about a constant region. VDJ rearrangement is for the variable. It doesn't make sense :(
pg. 47 on FA got the good visuals!
COPII* proteins are needed to coat vesicles from the RER to Golgi. "Two(COPII) steps forward; one(COPI) step back."
Anterograde goes RER -> Golgi -> Lysosomes/Secretory Vesicles -> Plasma membrane
why not small lysosomes?
and I thought large lysosomes due to lack of enzymes to degrade