NBME Answers : water's page

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submitted by medstruggle(7),

Why is it not ovarian follicle cells? I thought the female analog of Sertoli and Leydig is theca/granulosa cells.

colonelred_ Females can get sertoli-leydig cell tumors, which are notorious for producing lots of androgen. +3

brethren_md Females can get sertoli-leydig cell tumors, which are notorious for producing lots of androgen +2

sympathetikey Females can get sertoli-leydig cell tumors, which are notorious for producing lots of androgen +2

s1q3t3 Females can get sertoli-leydig cell tumors, which are notorious for producing lots of androgen +2

masonkingcobra Females can get sertoli-leydig cell tumors, which are notorious for producing lots of androgen +1

mcl Wait, but did anyone mention that females can get sertoli-leydig cell tumors, which are notorious for producing lots of androgen??? +11

mcl But seriously though, pathology outlines says sertoli-leydig tumor "may be suspected clinically in a young patient presenting with a combination of virilization, elevated testosterone levels and ovarian / pelvic mass on imaging studies." As for follicle cell tumors, granulosa cell tumors usually occur in adults and would cause elevated levels of estrogens. Theca cell tumor would also primarily produce estrogens. Putting the links at the end since idk if they're gonna turn out right lol Link pathology outlines for sertoli leydig granulosa cell tumor theca cell tumor +6

bigjimbo LOL +

fallenistand Females can get sertoli-leydig cell tumors, which are notorious for producing lots of androgen. +3

medpsychosis So after doing some intense research, UPtoDate, PubMed, an intense literature review on the topic I have come to the final conclusion that...... ...... ...... ...... Wait for it.... ..... ..... Females can get sertoli-leydig cell tumors, which are notorious for producing lots of androgen. +4

charcot_bouchard Hello, i just want to add that Females can get sertoli-leydig cell tumors, which are notorious for producing lots of androgen +1

giggidy Hold up, so I'm confused - I read all the posts above but I still am unsure - are sertoli-leydig cells notorious for producing androgen? +1

subclaviansteele Hold the phone.....Females can get sertoli leydig cell tumors which are notorious for producing androgen? TIL TL;DR - Females can get sertoli leydig cell tumors = high androgens +

cinnapie I just found a recent study on PubMed saying "Females can get sertoli-leydig cell tumors, which are notorious for producing lots of androgen" +1

youssefa Hahahahaha ya'll just bored +2

water Bored? you wouldn't think so if you knew that females can get sertoli-leydig cell tumors, which are notorious for producing lots of androgen +1

nbmehelp I dont get it +

redvelvet how don't you get it that females can get Sertoli Leydig cell tumors, which are notorious for producing lots of androgen? +

drmomo what if this means..... females can get Sertoli Leydig cell tumors, which are notorious for producing lots of androgen +

sunshinesweetheart hahahaha this made my day #futurephysicians #lowkeyidiots +

sunshinesweetheart @medstruggle look up placental aromatase deficiency (p. 625 FA 2019), it would have a different presentation +

deathbystep1 i am sure i would ace STEP 1 if i only knew that females can get sertoli-leydig cell tumors, which are notorious for producing lots of androgen +1

noplanb Wait... I might actually never forget this now lol +

drmohandes Females can get sertoli-leydig cell tumors, which are notorious for producing lots of androgen. +1

lilmonkey Don't forget that females can get Sertoli-Leydig cell tumors, which are notorious for producing lots of androgens! You're welcome! +

submitted by mousie(88),

is this subacute endocarditis associated Membrano-proliferative GN?

jus2234 The question describes how he had a strep infection 15 days ago, and now this is poststreptococcal glomeruloneprhitis, which can also be described as proliferative glomerulonephritis +7

seagull The question would be too fair if it just said PSGN. Instead we need to smell our own farts first. +29

yotsubato And they used terminology NOT found in FA +5

water who said they were limited to FA? +1

nbmehelp FA uses the common nomenclature and the fact most of our other resources use the same nomenclature for this, I think we can agree that is is the accepted terms. If they're gonna decide not to use the nomenclature that most medical students are taught then they should provide their own study materials at that point for us to use. The test shouldn't be this convoluted for no reason. +1

submitted by medstruggle(7),

Can someone explain why does this patient have hypokalemia?

colonelred_ Catecholamines activate the Na/K pump, which will drive K inside. +5

trazabone Read online that catachelamines are released following tonic clonic seizures. Besides that, BP of 180/100 could indicate that catecholamines are circulating. +1

fulminant_life This mechanism is why giving albuterol for hyperkalemia works +4

nbmehelp Why does this guy have increased catecholamines tho +

johnson His SNS activity is seriously increased --> increased catecholamines. +

nbmehelp Why is his SNS activity increased? Is the BP literally the only hint? +

youssefa Alcohol withdrawal creates a hyper- catecholaminergic state + Seizures do that as well. +1

water My best guess is that withdrawal puts the body in a state of stress (same for seizures) and with stress you have release of catecholamine which we'll see in the BP and the hypokalemia. +