need help with your account or subscription? click here to email us (or see the contact page)
join telegramNEW! discord
jump to exam page:
search for anything ⋅ score predictor (โ€œpredict me!โ€)

NBME 20 Answers

nbme20/Block 1/Question#47 (reveal difficulty score)
A 60-year-old woman with type 2 diabetes ...
Rupture of a papillary muscle ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
tags:

 Login (or register) to see more


 +6  upvote downvote
submitted by โˆ—hayayah(1212)
get full access to all contentpick a username

The two most important MI complications that occur within a 2-5 day span are papillary muscle rupture and interventricular septum ruture.

Papillary muscle rupture leads to severe mitral regurgitation, heard as a systolic murmur at the apex.

get full access to all contentpick a username
dulxy071  I disagree. any sort of rupture is usually the result of the action of macrophages (to eat away dead, necrotic tissue) which come in on day 3. This was merely a word game to get the time line right. They said "TWO DAYS LATER" (keeping in mind our time line starts 16 hours after the first symptoms appeared in this stem) which actually turns out to be day 3 +6
leaf_house  Wouldn't necrosis of the interventricular septum create a VSD, which would also produce a loud, (holo)systolic apical murmur? I don't get how we're supposed to differentiate, here. +1
mangotango  A VSD produces a holosytolic, harsh-sounding murmur loudest at the tricuspid area, not the mitral (apex) area -- FA, pg. 288, 289. +5



 +0  upvote downvote
submitted by โˆ—queenofhearts(18)
get full access to all contentpick a username

This patient has some characteristics of myocardial infarction including a sudden onset of severe โ€œcrushingโ€ substernal chest pain that radiates to the left arm, shortness of breath, and jugular venous distention (JVD). Complications of myocardial infarction include cardiac rupture which is seen in this patient. The effects vary with the site of rupture; from the patientโ€™s mitral insufficiency {i.e. systolic murmur at the apex} we can see that this is a rupture at the papillary muscle.

Resource Kaplan Pathology Page 94-95

get full access to all contentpick a username



Must-See Comments from nbme20

amorah on Cytomegalovirus infection
masonkingcobra on Contact with parakeets
hayayah on Capillary hydrostatic: increased; ...
hayayah on X chromosome-linked isoenzymes
medbitch94 on Mannose 6-phosphate
hello on Capillary hydrostatic: increased; ...
hayayah on Osteoblasts
imgdoc on Hypophosphatemia
hayayah on Missense
celeste on 50%
justgettinby on Omeprazole
andrewk1 on Cold, dry air
yotsubato on Jugular venous pressure of 12 mm Hg
strugglebus on Drug effect

search for anything NEW!