NBME 20 Recombinational double-stranded DNA break repair (NBME Answers)

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NBME Answer🗽Explanations

NBME 20 Answers

nbme20/Block 2/Question#37 (reveal difficulty score)
A 28-year-old woman of Eastern European ...
Recombinational double-stranded DNA break repair 🔍 / 📺 / 🌳 / 📖
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submitted by ∗hayayah(1212)

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Defective homologous recombination is seen in breast/ovarian cancers with the BRCA1 gene mutation.

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johnthurtjr Ashkenazi Jews have a higher risk of inheriting the BRCA1 and BRCA 2 gene mutations, just another tip! +3

lebron james BRCA1/BRACA2 are involved in the repair of DNA double stranded breaks +8

samsam3711 Other answers: DNA Mismatch Repair: Lynch Syndrome (MLH1, MSH2) DNA Nucleotide Excision Repair: Xeroderma Pigmentosa +17

lovebug not about this question but... Defective "Non"-homologous end joining is seen in Ataxia-telangiectasia. :) +4

makingstrides DNA Base excision repair removed damaged, or not correct, bases. +

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