NBME 21 Hyperplasia (NBME Answers)

need help with your account or subscription? click here to email us (or see the contact page)

NBME 21 Answers

nbme21/Block 1/Question#42 (reveal difficulty score)
A 36-year-old woman undergoes a total ...
Hyperplasia 🔍 / 📺 / 🌳 / 📖
tags:

+8 upvote downvote
submitted by ∗nor16(70)

get full access to all content ⋅ pick a username

Gonadotrophs are the FSH/LH producing pituitary cells. No ovaries, no hormones, no feedback inhibition.

get full access to all content ⋅ pick a username

lovebug THX for great explanation. When I first saw this question, I mistook the gonadotrophs for endometrial cell. so I Choose atrophy. (even that pt undergoes a total hysterectomy) critical mistake... +5

+3 upvote downvote
submitted by ∗paperbackwriter(161)

get full access to all content ⋅ pick a username

This can be analogized to menopause. Lack of estrogen ––> no negative feedback to anterior pituitary ––> increased levels of FSH and LH

get full access to all content ⋅ pick a username

+2 upvote downvote
submitted by ∗beeip(141)

get full access to all content ⋅ pick a username

[moved to subcomment]

get full access to all content ⋅ pick a username

+1 upvote downvote
submitted by halux(14)

get full access to all content ⋅ pick a username

can some one please explain why is the hyperplasia?

get full access to all content ⋅ pick a username

beeip Loss of negative feedback from resected ovaries leads to gonadotroph hyperplasia. +2

halux so, the explanation is that in the absence of Estrogen negative feedback inhibition to LH and FSH, this leads to Gonadotrophs Hyperplasia at the Pituitary resulting in elevated LH and FSH secretion levels? I get busted by this one :/ Thanks in advance! +14

nala_ula @halux exactly, there's no negative feedback telling them there is an increase in the hormones (since there are no ovaries) so gonadotrophs work in overdrive to keep stimulating the gonads via FSH and LH. +1

+1 upvote downvote
submitted by ∗blue4415(4)

get full access to all content ⋅ pick a username

can Gonadotrophs “hyperplasia” rather than hypertrophy?

get full access to all content ⋅ pick a username

kevinsinghkang wondering the same +

escherichia95 Hormonal stimulation will lead to production of new cells from stem cells i.e. hyperplasia. Hypertrophy is gene activation, protein synthesis and production of organelles. +

-1 upvote downvote
submitted by halux(14)

get full access to all content ⋅ pick a username

[moved to subcomment]

get full access to all content ⋅ pick a username

Must-See Comments from nbme21

nosancuck on Absorption atelectasis
assoplasty on Free T4
seagull on GM2
lnsetick on Apocrine
niboonsh on NMDA receptors are blocked by Mg2+ at the ...
drdoom on Deletion of a hydrophobic amino acid ...
hayayah on HCO3− transported in the plasma
mcl on Aortic
notadoctor on Usual interstitial pneumonitis
madojo on Genital herpes
hungrybox on Obstruction of the bile duct
jambo2222 on Lung
hungrybox on Mismatch repair
hungrybox on Hydrochlorothiazide