Quoting Dr Sattar, if an injury or cut is too deep so as the regenerative/stem cells are removed/damaged - then healing can only occur by repair. Thus, in this case, the stem cells of the lung aka Type 2 pneumocytes reside in the basement membrane - so, injury to basement membrane would damage type 2 pneumocytes and would NOT allow restoration of normal lung architecture. That's why maintenance of basement membrane integrity is the most important determining factor to distinguish whether tissue will heal by regeneration (restore normal architecture) or repair (fibrosis/scarring). Same concept can be applied to skin (basal cells) and intestines (crypt cells).
uoY avhe to thkin atobu it itsh wya: teh semenbat nermeamb si eth ”sgfofnl“caid no chhiw vr[rset]iatoe ngeahil ocr.suc So, se,y esmt slcel ye(tp II motcpenesu)y oduwl be elvinovd ni ttha ignhlae rssoecp but they dulctno’ eoestrr hte rlonam ehttuacecrri o(n“ tliia”bmaoe)snr toitwhu eth ken‘’eslot fo eth bnaseemt nmemrbea itgelln temh reehw ot ,og ni awht ctieornid ot go,wr hwchi ayw si ”p“u, e.tc If eht abneetms bmmaener si dretsedy,o yuo can litls tge eahg,lin tbu ti to’wn eb ozianegrd haenlgi -- llt’i eb soizddrineag ,ielangh ihwhc eosd otn paepar as lnmrao etss.iu zoriginsDad(e gleanih is tebtre nhat no ,niehlga ubt hiowtut a B,M teh reianegentrg llces to’nd veha nay oicidre“n”t and teoeerrfh ntc’a srteroe the lonmra ituhrertc).cae
I lduwo ikhnt lnsroiuote lsevoivn the emts lcesl p(eyt II tcmun)espoy.e Is eht tncait tebmnase emmnraeb eth anwser bcasuee it lmtsii dpear?s
anc oanney lpnxiae hwy ()D paeimsaalt is ?oetncrirc
submitted by ∗bubbles(79)
It can be re-accessed by making a purchase.
Purchase your membership here
$279$49 65% OFFmteasnBe mbrnaeme retgyniti si eht itadremnnet of lulf gnul evcoerry gnliolwfo ynplaorum tulin.s
ySmaur:m
)(1 slso fo mbntaees meabnmre rgtnyetii is iticarlc in einiendrgtm het o“tinp fo on utner”,r nad trtnbeiosuc ot the ilnabityi to ssbhlrteiea monlra nglu actietcrheur tiwh tmopronoi of osisri;fb
()2 loss fo eleliipath llcse, ehdlliatneo esc,ll dan stmebean enemrbam ntgtriiey in usaul tirienaitlst opnnauemi essiaactdo twih itaihdcpoi lpaonmryu ofsirbsi edsal to deoyetrsd gunl ccereaurthit adn peuapretl sf;iribso
)3( gstamnnfirro hgrotw cβat-rof si cesr,yeasn tbu ton tyneeril ii,fefsntcu to repomot npemenrat bs;orfisi
)4( iesespnrtt neuyta/jgnrirnin/ittira si riclacti fro eth nrapoipoagt of ibssi;ofr
5() tapdoihcii orlanpmyu fsborsii si an elxmpae of a orsspec eaedtlr ot eht enisrtepesc of an “n”i(g)tea,sn nrcoich ntlaiafion,mm and iisosf;rb adn
()6 uiequn slcel rae ciltairc erulclal arlpsye in eth tlnouigaer fo bssfiiro.
:aici nttowlbctth/2mmMwh1/inwi4/nrse.p.p..vn6lts//2:gi4c5oPCa/c
$279$49 65% OFF