effect of glutamate antagonist on pt with acute cerebral infarction = targets NMDA receptor
decreases calcium entry into neurons = decreased excitotoxicity = promotes recovery from acute cerebral infarction.
oTugh ioqne.ust
lalceR ttha neaMitmne hearemzs'li( dgur) is a MAND tecpeoRr tAaotsgnni ahtt hlspe rnevtep tteoyocxitixc by lkniBcgo C2a+ entyr. sTt'ha ohw I rebermme itsh.
a picture for better understanding https://2e.mindsmachine.com/asf04.02.html
^ link is dead :( (they published a 3/e) but here is the re-route to the new site if anyone wants to dig in https://learninglink.oup.com/access/watson3e-student-resources
MADN tsecreorp in shit ecsa rae bgnei esud for ognl etrm onintiapetot wihtin het bairn nda out of lal of ether icoeshc noly itsh pcreerto suse Ca+
I dkcpie NADM bueeacs ’tsi ysat,otimrul tbu is erhte nay preede soearn rfo ?ihts
oYu nac wenasr by cpesros fo onii.atimeln timCpotv"eie rtc"itonineas amkse uoy itkhn aumsyttliro N.T ssCro tuo BAGA adn cg.eynli In the eoxrtc so tlam.tgaeu pcMoattbeori duwlo enma hsetre' eodsnc nsmsesgere livoevdn nad teh oecterrp doulw not starnmit ilm.cacu eHecn NDM.A
dsue ni gnlo mert ntiopaotiten n(,galgeau ,moyemr) ayM lsao aypl a loer in enge ratiriotpnnsc in ornunes
)1 NMDA si a ealtumatG ecerropt pysetu2)b APAM si a esbtypu of DANM thta si iylainilt tidveacat yb agamluett e ls3eaer) DMNA sprerctoe era nufod rnae AAPM retrsopec utb ear not aaeditvtc by lwo velesl fo agaltemut seealre due to a gM noi kcgbnlio’‘ teh )nca nleh4 erequntF noAcit natpietlo ;t—&g isaimntotlu of PAMA g—t&; aoirdlezsep opst ytacispn norune —;> olagtev tepddneen Mg kclob fo DNAM pocerrte vedomer 5) lxiufn of Ca hgturho MDAN ;g&t— cesaus even omre AMPA proetecrs ot eb sditener itno het bnaemmer OEN:T( MAPA si srpeeoisnv to Ca nda teu mtaa)l6)g sBueeca erteh rae rome toepesrcr ot eorspnd to i,t hte elcl si rmeo eesrsopvin to umlgeatta
lla hte thoers a ctemntponioeiv inecs teyh have tpecyieii(cpifcifscs g)i,dnasl DAMN is the yoln oeiee(esncnlnhvcte vttceipieom eocrp,ert) has a agidnl etis dan ac , an dan hgmen..c.e emtvicepito
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$279$49 65% OFF,oS for msoe r,snoea onemsaustrenrrtti is hegitsnom vIe' WSAYLA utgdrgles .w.hti. pyrbolba ebescau I a'twsn guhatt ti lelw so vener yrlela dnelera it, jstu adeenlr hegoun rfo wahveetr .maex I just dfonu shti obo hutgroh CNBI and ist CFAST!AINT 'stI omrf 0201 os mtghi eb d,lo tbu ti saw ga.rte You acn arcshe tgohhur eth ookb dan nfdi hte easprch.t I tytepr uhcm tujs wtne hrgohtu all of eth ttmersteariunron cte.rpha bw9ss.tmo0tBknip/.nw7:ol/N9wg./hh/1v./Kicobn
My anmi ae-y:saa Galuemawttkt = jrmoa eaorxtyitc nsrntt.tiroeaerum wTo eystp of r)ote :rs1epc tpbooai,cmert omst of hhwic era patpinrescy Gi hchwi aleds to eadrsecde NDAM rprceeto tiyiavtc nad iksr fo ,tocxxiieoyctiti ro toypcpstsani Gq oesrprcet ttha lade to cisneera a,N+ ,K+ and eededasrc tautlgame uecass loondaepzritai and erndaicse +gM+ lacsnmedpeit dan MDNA trreoecp cvttiiay dan srki fo ytxtie,tioxcioc dan )2 niirtpoooc hnncalse udinlgcni MNAD dna enPMaaAtki/A haelcsnn, ihchw lla lolwa nfeipcocisn oitnca fi,lxnu ubt yoln NMDA swloal +aC+ inxluf adn( onyl in a vgleato endependt emnran tefar tsfcefiinu liaozedarionpt hsa lepcaisdd eht nohriitib Mg++ ion in eht nlh.a)enc
AGBA nad licegny = yiintroihb tsrreos.tnritanume )1 AGA-BA adn AGB-CA = tpnrcoioio seanlnch that dlae ot efxlu of C-l, nda itpesed tsih isacngu nter,aidpiazloo eht nronue sllit yasts lobew ntrigse ati.onplte A-AGBA nniidbg ites orf sart,iuatrbeb odrs,ties AAB,G dan cxoipintor = disein orpe of nlc.ehna BAG-AA gnibdin ties of eboedinizpszena = uesdoit fo oper of .cnenhla )2 ycinGle anlnehc si a ryev iiamlrs C-l lxeuf cneanl.h 3) BAA-GB is a ctooarimetpb nhlcnae ttha eavstitca Gi glndeia ot ederdaesc McAP ichhw taisteacv elfufx +K lnsecnah dan ishitibn +Ca+ xlifun lacnnshe ginldae to haopyrzrilpeaint.o
ingcoiBe naiems = olmsnteciaceah ainmpedo inira(docntoo of ydob e,mvteomn r,wraed oaomittnv,i ,etnincoemrr)ef rnoneprpiihene (slepe, sufklne,wase ottaninte, niedgfe a,heirbov heepernpiin twose(l cnitrtcoonnea in S),CN plsu ntesrnioo le(sep, en,suasfwlek nips,redseo nayxte,i u)naaes dna emhiisnat or(,lsuaa taneott,in agll,rye tisesu admgae, and mya efneinulc oldob irban )ofw.l v,bsoyuOil lla fo shit si ni dtaiiond to raengcidre oromnsrnnsuitasei dan ,lghift ftihr,g nda itfhg noper.ses
PTA dna hroet reisnup = ictyxoarte stnn,arioissm eds-ecorael tihw horet ceaull-emlolms trrs.tueinmteanrso nndAoesie ist'n alaicsslcly seeirdcdon a ermenrattosntuir secebau it t'isn eeddel/arstoesr in +a+C enpednedt ae,rnnm tub ieddver mfor APT boefer gnhaiv an cytaiorext p.tnlateoi
leyhlntccieoA = oajmr rttritnesroanmeu onelvivd ni rtrmoassnsneuonii avi mniarucs dan ictcniion .csotprere
deptePi otsntarmneetrursi = lnoyocmm delesare as rieopepdpt erlagr roprecssru ttha rea ledcave yb iseicfpc seneyzm ttah erwe in the amse tmtutaeseornnrir viceesl nuop lsr.eeae Fevi tsyep = /iagnurbt pespt,edi doioip ,dpisetep ryaiputit tp,idesp apaoihtchlym riegnleas o,sohrmen and hoest nto a.cidfelssi xsEeapml = surcerorp atht esgiv srei ot ubsntaesc P ppchpi,(asmuo xoerocn,et nad TIG dan esreedal from llams edeitarm NPS C sbirfe that ramitsnt pnia dna tptrreeameu nanori,ifmto oweufrlp opniv,yhetes niietbdhi by dipooi ies,dptep) irknuoinne A, dpoteerenuip K, nda eoiuterdppne mmgaa, dna ipodoi speidtpe ingdncliu ptlan ldikolasa k(eil mi,)eropnh isctyneth iodoip vvrtee,asidi and ispedn,onrh sn,pnyidorh nad ieplenask.nh In engarle oioidp itedsepp are atdpsessnre .i(.e laeingsaa asihcnm,me) ivonldve in pemxcol bhiosrvea auex(ls antrtotic,a igsmusigv/sbsaseerive vo,hibesra) dna talimcidep thho(gu tno ei)dfintvie in cihyarsiptc ssrd.idoer
,alOelvr trnauossirtertmne = type syept: ll-eaesllmmocu rsaritmtetns dan se,tprpnudeioe wereh oecelsm-slulmal ismtraetrtns aer earsft dna deimeat apdri pyitcnsa nnrsstsiimoa .i.e( aergnond NSS /r/hhlgtitihtfigffg kqcui ese,p)onrs weehr as npepoidtsreue ngola( hwti licgoboi mainse adn moes small oeluemlc atitmes)rtnrs ear swroel dna etdimae ardu,gla onlgdoepr uismnriesnan.rotos
eSom rieu:tpcs p:odnunskwtuhvecatb.eniit/tpi/empem_/dasfe.nttdpwmrh/e/slokorvt_w.u_raeihroeur, p-ew5hGpa8/d1cm/hsrt6.ws12.sbt3eaeeefgnRnrPodbt1-s6lr3cwuAB/cab20tp3u480rlt1id/u64Anr6a70roi/ias-f2-sabeifp9cTgB-eolga1e-gaerpereh4f--3d0//ti:gi0or, dna .a731i0wmx=gbbdrghaUrl-ew#rsgi.digbb5&/ntllpx8e2d/gaae=9eau-odw:61/t/-et-n_0hfe4s-c.ie2wt5eh-;fbl16pn1s3af/et-/a-adf
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