NBME 23 Area under the curve (NBME Answers)

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NBME 23 Answers

nbme23/Block 3/Question#10 (reveal difficulty score)
An investigator is studying two drugs, Drugs ...
Area under the curve 🔍 / 📺 / 🌳 / 📖
tags: pharm_calc

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submitted by ∗mcl(670)

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This is a nice quick refresher of what AUC is.

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focus https://step1.medbullets.com/pharmacology/107002/pharmacokinetics +2

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submitted by rossiememe(6)

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DOSE x F = AUC x CL

(F= Bioavailability)

If dose is constant and F is increased for Drug X then AUC would increase.

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melanoma and the cl? +2

cassdawg Clearance is independent of bioavailability as it is determined by the rate of elimination (affected by liver and kidney "clearance" of the drug, not the "absorbability" that is essentially bioavailability) +1

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