NBME 24 Scar formation (NBME Answers)

NBME 24 Answers

nbme24/Block 3/Question#35 (reveal difficulty score)
A 4-year-old girl has a history of multiple ...
Scar formation 🔍 / 📺 / 🌳 / 📖
tags:

+67 upvote downvote
submitted by ∗atstillisafraud(217)

get full access to all content ⋅ pick a username

Thank you NBME for the high quality pictures. It makes these exams stress free and enjoyable.

get full access to all content ⋅ pick a username

sympathetikey Feels bad man. +3

zoggybiscuits Those Sclera sure look blue. wow. +21

yotsubato the same girl shows up on so many NBME exams its not even funny. Its just like that poor kidney that's cut in half that shows up in all kidney questions. +15

aneurysmclip I turned my brightness up and down 2 times to make sure it wasn't my brightness messing with the sclera. I'm declaring it, NBME stands for "Naturally Bad at Making Exams" . +6

peqmd $60 a pop and no competitors...That's what happen when there's a monopoly. +9

peqmd Actually they used their best software to generate images. You might have heard it before, it's called MS Paint. Quite legendary. +9

feochromocytoma It feels like they cranked up the contrast and saturation on a normal eye to make it look "blue"... +6

rockodude everyone hates on nbme, but they're showing you a picture zoomed in of her eyes and she has a history of multiple fractures/bad wound healing at the age of 4, I feel like OI should at least be a consideration based on the overall clinical picture +1

feochromocytoma Yeah I got it right, it's just funny that they don't use higher quality pictures for the exam +1

djeffs1 that is clearly a malar rash... oh wait nvm just pixellation +4

+20 upvote downvote
submitted by ∗itsdrgoodwood(20)

get full access to all content ⋅ pick a username

The diagnosis is Osteogenesis Imperfecta. Disease causes a defect in Type 1 Collagen that leads to “brittle bones”, meaning the patients have frequent fractures with little trauma. Type 1 collagen is also a major component of the sclera -> this is what the picture was hinting at (i think?) and it causes “blue sclera”. The sclera are thin/translucent so they look blue due to underlying choroidal veins.

Finally, patients have poor wound healing. Wound repair with granulation tissue involves type 3 collage which is then converted to type 1 collagen during scar formation. Defects in type 1 collagen obviously don’t allow this process to take place.

get full access to all content ⋅ pick a username

+9 upvote downvote
submitted by ∗misterdoctor69(70)

get full access to all content ⋅ pick a username

Damn everyone out here looking at the eyes when my dumbass was thinking the girl was missing a nasal bridge or something lol fml

get full access to all content ⋅ pick a username

peridot That is straight up what I wrote: "low nasal bridge???" I was like is this part of some congenital defect +

mkayman lmfao +

+3 upvote downvote
submitted by ∗adisdiadochokinetic(89)

get full access to all content ⋅ pick a username

It really looks to me like her sclera have been photoshopped, anyone else notice that? xD

get full access to all content ⋅ pick a username

+2 upvote downvote
submitted by ∗gainsgutsglory(38)

get full access to all content ⋅ pick a username

She has Osteogenesis Imperfecta. Aka “Brittle Bone Dz” aka Collagen Type I deficiency. U need collagen type I to make scars (granulation tissue is type III and then metalloproteases and zinc cofactors help digest into the firm type I collagen).

get full access to all content ⋅ pick a username

wowo FA 2019 p51 +

+2 upvote downvote
submitted by ∗syoung07(58)

get full access to all content ⋅ pick a username

fam I had almost convinced myself I was looking at some epicanthal folds

get full access to all content ⋅ pick a username

+1 upvote downvote
submitted by ∗sweetmed(157)

get full access to all content ⋅ pick a username

I legit thought her oversized pupils were the problem. What genius decided to use this photo.

get full access to all content ⋅ pick a username

-1 upvote downvote
submitted by ∗j44n(141)

get full access to all content ⋅ pick a username

Just another piss poor government institution cutting corners. If you've done NBME 18 and seen the cell diagram figure it is the literal pinnacle

get full access to all content ⋅ pick a username

drdoom the NBME is a private, for-profit corporation. individual U.S. states use its products (i.e., the certification it gives you when you pass their exams) to determine your eligibility to practice in their state. but they are not a government entity. +1

Must-See Comments from nbme24

seagull on Intestinal mucosa
tissue creep on Ask the roommate not to smoke in the apartment
drdoom on Adenosine
seagull on Increased serum testosterone concentration
atstillisafraud on Lamins
niboonsh on Only cookies are independently associated ...
atstillisafraud on Scar formation
lamhtu on Decreased adherence
drachenx on Damage to the rectovaginal septum
drdoom on Intestinal mucosa
azibird on Coronavirus
lsmarshall on Organic acid metabolism disorder
sympathetikey on Inhalant abuse
tea-cats-biscuits on Eosinophils