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NBME 24 Answers

nbme24/Block 3/Question#45 (reveal difficulty score)
A 59-year-old woman has a 10-year history of ...
Neural crest cells ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
tags: neuro

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 +14  upvote downvote
submitted by โˆ—neonem(629)
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Cerebellopontine angle mass = Vestibular schwannoma (AKA acoustic neuroma). Derived from Schwann cells, which are of neural crest origin.

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yotsubato  Ugh. Of course they dont put schwann cells as a choice. So I pick oligodendrocytes like a dumbass +41
subclaviansteele  Same^ +1
madojo  Schwann cells = PNS Oligodendrocytes = CNS +3
suckitnbme  NBME loves their neural crest cells +4
wrongcareer69  How much do they pay these testwriters anyway? I can use a thesaurus too +2
osteopathnproud  @suckitnbme they do love their neural crest cells, I have chosen neural crest cells for every single answer choice I see it in and I believe I gotten 90% of them correct, if something doesn't click or you don't know, I would keep neural crest cells as a very possible answer lol +1
faus305  AMERICA EXPLAIN +
failingnbme  I know this was Schwann but my brain fart and chose oligodendrocytes! +



 +2  upvote downvote
submitted by โˆ—abhishek021196(119)
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COPS: CNS = Oligodendrocytes, PNS = Schwann cells.

Neuroepithelia in neural tubeโ€”CNS neurons, ependymal cells (inner lining of ventricles, make CSF), oligodendrocytes, astrocytes. Neural crestโ€”PNS neurons, Schwann cells, glia, melanocytes, adrenal medulla.

In CNS (including CN II), myelin is synthesized by oligodendrocytes; in PNS (including CN III-XII), myelin is synthesized by Schwann cells.

Since CP angle mass is a vestibular schwannoma, it arose from Neural Crest cells.

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 +0  upvote downvote
submitted by โˆ—madojo(212)
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Going over other choices (FA 19 514): Oligodendrocytes are part of the CNS so a tumor there would be an oligodendroglioma which is relatively rare, and in frontal lobes. On histology you would see fried egg appearance with chicken wire capillaries. Glioblast tumor would be a glioblastoma multiforme which is common and has a 1 year survival, its the one with the butterfly glioma crossing the corpus callosum.

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overa  GBM comes is an adult astrocyte tumor +
overa  ^ this guy doesn't know how to speak English +
cienfuegos  ^made sense to me. English is challenging and you're doing just fine. Keep pushing! +1



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