A 14-year-old girl is brought to the physician for ...
Li-Fraunemi syndrome = SBLA (sarcoma, breast, leukemia, adrenal gland syndrome) and occurs because of an autosomal dominant inherited mutation of p53
APC: linked to FAP (colorectal cancer)
RET: linked to papillary thyroid cancer, MEN 2A, MEN 2B
The thing that threw me off was that the only connection in her FH to the above SBLA reference was the mention of a paternal cousin with adrenocortical carcinoma. The other two mentioned had brain cancers, which seem completely outside the scope of the above mnemonic. Then again, as mentioned elsewhere, I suppose the best policy on these is just to rule out the absolute wrong answers.
I swear, the NBME is lying when they tell us to choose the "best" answer on some of these. What they actually mean in practice is for us to choose the least shitty.
^ this guy cracked the code. nbme ur doomed.
@privatejoker: I feel the pain. Quick FYI: UW includes brain in the associated tumors.
we can just make her thing SBBLA and hopefully never get this wrong again