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NBME 22 Answers
A 35-year-old woman has weakness and fever. When ...
Acute myelocytic leukemia
Additionally, AML is the only answer choice that has multiple blast forms (myeloblasts, promyelocytes, etc.). ALL is characterized by a single blast form (lymphoblasts).
CML has blasts too but they tend to favor mature forms.
You see numerous blast forms == AML, which is characterized by >20% blasts
The answer choices are all of lymphoid origin except for AML and Hodgkin Disease. We know Hodgkin Disease is a lymphoma (not leukemia) and would present with lymphadenoapthy. So the answer must be AML #testtakingstrategies
@atstillisafraud thanks for mentioning the merchlorethamine increasing risk for AML, i was trying to make a connection with the drugs but couldnt. Had to lean on the test taking skills just like key company
Procarbazine is alkylating as well.
thanks for the reminder, often overlooked are the simple demographic hints. helps you make an educated guess
also a key thing to remember in general is a person who undergoes chemo is a big demographic hint to later developing AML regardless of the clues :) and yes the AGE!!!