welcome redditors!to snoo-finity ... and beyond!

NBME 22 Answers

nbme22/Block 4/Question#20

During a study of symptomatic proximal deep venous ...

Open-label clinical trial

Login to comment/vote.

 +1  upvote downvote
submitted by aesalmon(35),

Clinical trial - compares therapeutic benefits of 2+ treatments (warfarin vs. dalteparin) Open-label - both the health providers and the pt are aware of the drug being given





 +1  upvote downvote
submitted by hello(64),

Why isn't this a cohort study?

drdoom  This is a cohort study! (Since it involves splitting people into "groups"; group = cohort.) But the stem asks what "best describes" the design. So, yes, it's a cohort study but a more precise ("more specific") description is Open-label. In other words, "Open-label clinical trial" is a type of cohort study, and, in this case, "Open-label" is a more precise description of what is described in the stem. +1  
drdoom  For a more technical explanation of "Cohort studies", see the definition from the National Library of Medicine: https://meshb.nlm.nih.gov/record/ui?ui=D015331 +  
angelaq11  It is a cohort, just as @drdoom said, but it isn't an "Observational" one. +  




 +0  upvote downvote
submitted by niboonsh(76),

I am confusion. why wouldnt this be a cross over study?

shokay  there is no washout period and the order of drugs given isn't switched +1  




 +0  upvote downvote
submitted by ahmedfuc(0),

cohort is observational study so you just see what is result of exposure in clinical trial we do intervention like giving medicine and comparing its eficacy to control therapy





 +0  upvote downvote
submitted by ahmedfuc(0),

cohort is observational study so you just see what is result of exposure in clinical trial we do intervention like giving medicine and comparing its eficacy to control therapy