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 +0  visit this page (nbme13#1)
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So I think where I got tripped up is that she does, indeed, have multiple myeloma (so there will be increased serum IgG), but the thing that is actually causing her bones to show the osteoclastic lesions shown in the image is IL-1 (osteoclast activating factor). Weird wording. Thanks NBME.

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 +2  visit this page (nbme20#5)
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Could anyone help me on why this couldn't be C (facial portion of the homonculus in the primary motor cortex)? It explicitly mentions motor issues with the face - not just speech. I understand why it would be Broca's - that's what I put originally. But the last sentence mentioning motor disruption caused me to change my answer. Thanks.

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jaeyphf  I didn't even think about the motor part during the question, but it might be related to the homonculus (FA 2020 pg 502). Motor and sensory areas of the lower face generally fall towards the lower half of the brain. Answers B/C/D would probably show some hand or arm involvement. +1
bbr  I know this isnt a great answer, but I was assuming that they wanted us to "play the game" and decide broca/wernicke. It seems set up for us answering that type of question. Going off buzzwords like "fluency", "phrase length", "comphrension". +1
ekraymer  I believe that if it was section C, then the patient would present with something like slurred speech. "Fluency" and "phrase length" wouldn't be affected since it's purely a motor problem in section C. +




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