https://jamanetwork.com/journals/jama/fullarticle/2775792

^ Important read, if you have the time.

Tacrolimus has the same MOA as cyclosporine

This question is describing what is literally called "Head Out Water Immersion." The pressure that the water exerts on the body is greater than the pressure that air exerts on the body. This hydrostatic pressure pushes the water in the limbs up into the central cavity (the rib cage protects from this hydrostatic pressure). Because there's more blood in the central cavity, the heart experiences an increase in volume. This is why you often need to pee more often when standing in the pool.

In summation: water pushes blood into center cavity -> increased blood volume in central cavity -> blood stretches heart -> increase in ANP

The owners are a bunch of assholes they just took everyones descriptions and are now trying to make money off of it you guys are useless

The owners are a bunch of assholes they just took everyones descriptions and are now trying to make money off of it you guys are useless

"clear-fluid-filled, tense blisters" and "subepthelial blister" with "autoantibodies" scream bullous pemphigoid, but I thought BP blisters were itchy>>painful. Contrast with pemphigus vulgaris in which pain>>itch.

Pt shows classical signs of lack of platelet ADHESION. ADHESION is mediated by vWF. Platelet AGGREGATION studies test for AGGREGATION, which is mediated by fibrinogen, thus they have normal results on lab testing as they are not testing a pathway that uses vWF (very miniscule detail I know, very annoying).

Because it is a straight downward slope, you can also tell that Y and X are bound in similar ways by antibodies. What differentiates the two, then, isn't epitope binding capability, but the concentration. All else equal with binding sites, more Y with an unchanging amount of X will lead to less X bound, in a 1:1 manner.

Don't need to know this is FAP to get it right.

Father and Grandfather had it, so can assume an AD mutation in this patient. Assuming her partner is homozygous without the mutation, the risk of her AD train going to her child is 50%

RIPE: Rifampin, Isoniazid (INH), Pyrazinamide, Ethanbutol.

RIPE treats TB.

Side Effects:

• Rifampin: Red-orange metabolites. Skin/fluids can become red-orange. 'R'ifampin makes you 'R'ed
• INH: Drug-induced lupus (DLE), iron accumulation in mitochondria (can lead to sideroblastic anemia), neuritis, and hepatitis. Give B6 for neuritis and SB anemia. INH has 3 letters like DLE
• Pyrazinamide: Hyperuricemia (gout). pURICinamide
• Ethanbutol: Effects eyes. Decreased visual acuity, red-green colorblindness. EYEthanbutol

Compression of the C5/C6 spinal nerves would mean the axillary nerve is compressed.

(Use the mnemonic: 5 Muskateers Assassinated 5 Rats 5 Mice, and 2 Unicorns; assassinated would be C5/C6 and axillary sounds like assassinated)

The axillary nerve innervates the deltoid muscle which abducts the upper extremity.

Bacterial vaginosis is also very common in women/people with vaginas who have sex with women/people with vaginas, and more common in that population vs gen pop.

One 2005 study of 12K vagina-owners found 45% prevalence in folx who'd had at least one partner with a vagina, vs 29% rest of study population.

(Sorry no link, just sharing from "Lesbian Health" by Dibble & Robertson.)

Hydronephrosis causes tubular atrophy from compression of the tubules by urine. Two common causes of hydronephrosis in infants and young children include pelvic-urethral obstruction and vesicourethral reflux.

Reflex erection--> somatic tactile stimuli to penis Can still happen if a spinal-cord transection occurs cranial to T10/T12.

verses

Sympathetic--> psychogenetic erection Males with cord transections above T9 are unable to achieve psychogenic erections.