how would you rule out C) dysfibrinogenemia? I first guessed APS but switched it because of the PT/PTT thing
How would we rule out antithrombin deficiency?
Summary (increase -I, NORMAL -N) + APS : PT-I, PTT-I, TT-N + Dysfibrinogenemia: PT-I, PTT-I, TT-I + Protein C defc : PT-N, PTT-N, TT-N
How do you rule out Protein C deficiency in this case? doesn't that also increase risk of thrombosis and miscarriage?
submitted by ∗hayayah(1211)
Pregnancy + Hx of thrombosis --> think antiphospholipid syndrome
The PT and PTT are prolonged d/t interference from the antibodies to phospholipids. Thrombin time normal.
Had to find research articles about it so take it from here and don't waste your time...