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nrgeyaPnc + xH of irbomsosht ;t-&g- thkni tpdloisohpahinpi nsordyme
hTe TP adn TTP rea rdgoplneo /td etecnnfreeir orfm hte atnbdoiise to iopls.hoidshpp obhiTnmr emti rlanm.o
adH ot fdni rsaherce treasilc autob it so ekat ti ofmr rhee nad to'nd atswe rouy ei.m.t.
monolocoyeah, iβve never heard of antiphospholipids increasing PT time ...+222019-06-01T22:20:36Z
goldenwakosuNot sure if that little detail was to throw us off. I think the point of the question was to ID antiphospholipid syndrome based on the clinical criteria (spontaneous abortion + thrombosis)+42019-06-01T22:22:29Z
johnthurtjrI actually went down a rabbit hole with this one recently - essentially in vitro findings =/= in vivo findings, clot-wise with anti-phospholipid antibodies. +32019-06-03T04:48:59Z
link981No mention of lupus anticoagulant, anticardiolipin, or anti Beta 2 antibodies. FA mentios prolonged PTT but nothing on PT. What a piece of shit question. But thanks to the dudes above who explained it+82019-07-03T00:58:23Z
yb_26UWorld mentioned "prolong aPTT (and sometimes PT)" in APS+32019-07-10T15:03:10Z
oslerweberrendu@yb_26 Can u please tell the QID because the one I have seen it says, "Although patients often have prolonged ptt (because the antiphospholipid interferes with ptt test), pt is normal."
QID: 1298+2019-11-06T02:31:07Z
kevinjust to clarify, lupus anticoag is in antiphospholipid and presents with paradoxical increased ptt +/- pt despite increase risk thrombosis+12020-05-17T03:16:42Z
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owh dwulo uyo leur uot )C fdaeisinnigoye?mrb I ftsri deuegss SPA utb dhwitsec it buacsee of eht TTTPP/ ihtng
suckitnbmeYou should be able to rule it out by the normal Thrombin time. Abnormal fibrinogen would have increased PT/PTT but also increased Thrombin time because the entire pathway is compromised by the inability of fibrinogen to be cleaved to functioning fibrin.+52020-01-11T18:01:24Z
How do you rule out Protein C deficiency in this case? doesn't that also increase risk of thrombosis and miscarriage?
suckitnbme@rainlad Protein C deficiency doesn't cause elevated PT and aPTT. I believe they're both normal and assays for the disease measure protein C activity.+42020-01-28T06:07:59Z
drzedProtein C is an anti-coagulant, so if you lack factor C, then you have MORE clotting factors. This means that the PT and PTT would not be prolonged. +32020-02-04T02:22:29Z
submitted by hayayah(1077), 2019-05-29T01:05:45Z
nrgeyaPnc + xH of irbomsosht ;t-&g- thkni tpdloisohpahinpi nsordyme
hTe TP adn TTP rea rdgoplneo /td etecnnfreeir orfm hte atnbdoiise to iopls.hoidshpp obhiTnmr emti rlanm.o
adH ot fdni rsaherce treasilc autob it so ekat ti ofmr rhee nad to'nd atswe rouy ei.m.t.