Pregnancy + Hx of thrombosis --> think antiphospholipid syndrome
The PT and PTT are prolonged d/t interference from the antibodies to phospholipids. Thrombin time normal.
Had to find research articles about it so take it from here and don't waste your time...
monolocoyeah, i’ve never heard of antiphospholipids increasing PT time ...+32019-06-01T22:20:36Z
goldenwakosuNot sure if that little detail was to throw us off. I think the point of the question was to ID antiphospholipid syndrome based on the clinical criteria (spontaneous abortion + thrombosis)+12019-06-01T22:22:29Z
johnthurtjrI actually went down a rabbit hole with this one recently - essentially in vitro findings =/= in vivo findings, clot-wise with anti-phospholipid antibodies. +12019-06-03T04:48:59Z
link981No mention of lupus anticoagulant, anticardiolipin, or anti Beta 2 antibodies. FA mentios prolonged PTT but nothing on PT. What a piece of shit question. But thanks to the dudes above who explained it+22019-07-03T00:58:23Z
yb_26UWorld mentioned "prolong aPTT (and sometimes PT)" in APS+12019-07-10T15:03:10Z
to snoo-finity ... and beyond!
submitted by hayayah(349), 2019-05-29T01:05:45Z
Pregnancy + Hx of thrombosis --> think antiphospholipid syndrome
The PT and PTT are prolonged d/t interference from the antibodies to phospholipids. Thrombin time normal.
Had to find research articles about it so take it from here and don't waste your time...