hTe tceconp si a euolvndtco awy of snkaig if uyo wken woh JVD inomoictbearn skrow, hhciw is tath ti is tlluacya an mpxeela fo atilengr hte AND fo hte /BT mlhyypoct.e

theuornS tlbo cqute:iehn So hnwe tyhe ues a ebpro gsatian osme ,oenigr and pitgttuuon a zeis fo 15. bk or 6 k,b siht si lgetlni uyo het szei fo eht NAD engfamrt ni cahe ecll tn’e(ods rmatet fi yhte ays J eoprb or csontatn ogiren roeb,p eyetrh’ ustj gaiyns e’rteyh etrnggtai msoe uldeinoetc eceseunq fnuod in the Ig CR/Touslc baet acihn clous ievlystrepec rfo BT/ lce)l.s

I inkht hte incfgunso ptra dcluo be nwodeigrn who oyu knwo wthrehe ’eyuor trlpya hthurgo targenmneerra wn(aers sechoci B hrtu )D ro fi it ah’nts dccreoru at all yte ccr(teor rae.ns)w ,eHre eht encctop si taht B csell erdugon (D)VJ gmetneraarenr ni het oben m,rroaw iwelh T leslc do it ni eht tu,hmsy and it lla phnasep ta ceo.n oS a palmas lcle in eth lodbo eilk in elltuiMp omyMlea dulwo ehav fluly rudoeegnn tnioaobenc,rmi liehw a T lcel in hte lbodo could rhteie eb lluyf edtdceau dan( vhae indeishf VJD mo)enaoibtcirn ro muaeirtm hn(t’sa tdeatrs DJ.V)

neiSc eht T elcl eegn swa 6 kb dna tyednieifl iegbgr hnta the .51 bk nge,e eth T lelc hsn’ta doneerung ninrcaobomite yt.e

rShto awes:rn lAl sngee rae tensrpe in othb B nad T s,lecl utb htey ergernaar and rsexpes ocepstrer that ear scficeip to treih lgi.anee Theri rea tdinpeneend DVJ ensroig orf B ecll ocpterre nntgieareo dan T clel torpreec rionen!tage This kwii rectlai ssehd lihtg no i:ths

b_tnto/t.redreio/(awnic)pDeew#imJ/lk.eTinpVokios/echrtcipgrs_l_:ia

I oot rligayalct edsmis htsi.. tub it si latucaly os pmseil atht we era nmiisgs the esrfto torhhgu teh rseet i Wl--eh hotb B nad T escll ngoedru DJV rgea,erenarnmt het V, ,D and J eegsn rae FINFDTERE EGSNE spiteed nebgi nagderzio and ehtrfeoer adeilisscf ni a lsmiair naosfih ued ot itehr aershd deen ot naeetegr evdsrei ctrstsreuu. oT kema tmtrase moer cio,nsgfnu thob sste fo VJD gsnee rae on coshmmooer 1.4

hisT si wyh eth BNME isfeecdpi ttha heyt era tanggig THE MESA J OIRNGE chhiw is ahtt of the B lecl trroecpe gene J ei,gnor nto teh T ecll eporcrte ngee tJeb-a ogiren e(se ikiw cal)rei.t Teh B lcel etroerpc egen si tno rreegnaard in a T l,lce if it ,asw T clsel dwlou aehv !sienaoibdt

hTe ayw I tuhgoht atubo siht utsoqine aws htta in MM erhet si a TON fo oisabtdein ngebi a,dme os eth JVD nestemg si nbieg bkorne cees/tedgrpeurlanear/d myan mseti nad has bnee esonhretd to 5kb.1. As rof hte T l,sCle atth rigoen stn’i negbi udes scne(i hteer is on olanlc pnnxioesa or sloeiecn)t os sti’ isllt tgo teh lufl bk6 genhlt nuthdoec.u

hWlie T lelcs od eus eht DJV boatnnocmeir,i het T ellc ecorerpt sacnhi aer rednftief eesgn mrfo het B cls'le ayhev nad light i.casnh enciS eyht edsu a B lecl roign-eJ b,roep het T cel'ls nabd liwl eb mchu lraegr sa htsi aera fo tis DAN e(ht B ecll ayhev or thgli nihca ge)esn vahe not nbee nargrdaeer -- eisndat sit T elcl reerctpo seeng evha eneb rer.adgenar

_nrqrainp/s_osz2/xsp7.so_4rht1e/nitmicn/idbmweoepol/etb/_2pntetmleqa:tuuoc_nebss.h/prmtetd/eelww_