eTh etnqious is renrfgrei to het samxohiene wayhtap.

yalraobmC toeppahsh and rnagiien era nodvlvie ni het auer yccle. oS is nt-ugyamcaatlelet AGN)( rule(sateg tornduiopc of olmraycba hh)etpaops.

I tried to use logic to answer this question (I did not know about the hexosamine pathway). Here is my attempt--this is probably wrong somewhere.

I figured that if you want to make glucosamine, you need to combine glucose + an amine group

(A) Arginine I knew was involved in donating nitrogen, but it is in the urea cycle, so I figured this was probably not the answer but it had potential. I figured that the major way this compound removes its nitrogen is through urea, though.

(B) ATP. Since F6P already has the phosphate group, I figured ATP is probably not necessary as the compound in question already has a PO4 group.

(C) Carbamoyl phosphate. I knew this was involved in both the urea cycle and nucleoside synthesis, so this was less likely. It also is the product of a NH3 and CO2 so that means that I wouldn't expect it to donate an amine group

(D) Glutamine I figured has an amine group attached to it ready for donation. I also know that transamination reactions are common with amino acids and alpha-ketoacids (e.g. alpha ketoglutarate with alanine can get you glutamate and a pyruvate via ALT) thus it made sense that an amino acid could donate an amine group.

(E) The only thing I knew about NAG was that it was used in the urea cycle as an allosteric activator of CPS, so I didn't think that it was useful as a donator of nitrogen since its function is to help aid nitrogen excretion.

So then I was stuck between A and D, but based on transamination reactions, I picked D.

you need to add an amine (nitrogen) and most biochem processes from sugar --> amine requires glutamine

If uyo tnaw to take a kolo for eth licinlca etanocipmr fo hte ixnmoehsea hyptaaw ;m&ap tprc:soud ei/a/wcw/hpxnosei/urehtcsmcodteceiciomc.:orsn/inptw.seteenscs

rcssoPe of eionmiialtn no this .neo

• I taediimenl alobyCrm shh,tpaeop renAiign ude to areu yc.cel
• I eeaindmitl PTA baucsee ATP nlaoe 'duntlwo echagn P6F noti ncesuimlgoa
• AGN I ogt clkuy dna I eadlienmti ti eud to tis ues ni CME dna gnollcae so I dtnd'i nhtik it saw ealvtnre nad I nkid of edrmebmere it iebng ni uear c.ylce