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Welcome to jaxxโ€™s page.
Contributor score: 26


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submitted by celeste(96), visit this page
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While the lifetime risk in the general population is just below 1%, it is 6.5% in first-degree relatives of patients and it rises to more than 40% in monozygotic twins of affected people. Analyzing classic studies of the genetics of schizophrenia done as early as in 1930s, Fischer concludes that a concordance rate for psychosis of about 50% in monozygotic twins seems to be a realistic estimate, which is significantly higher than that in dizygotic twins of about 10โ€“19% (ncbi.nlm.nih.gov/pmc/articles/PMC4623659/#ref3)

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imnotarobotbut  How is one supposed to know this before having read this article? +37
imgdoc  This question falls under the either you know it or you dont category. It isnt in FA or Uworld +2
jaxx  So why would these A-holes put it on there as if prepping for this exam isn't stressful enough :-| +9
doodimoodi  Lol just why seriously +3
champagnesupernova3  This was mentioned in the Kaplan behavioral videos +
usmlecrasher  and there's so much unnecessarily BS instead of real questions +3
j44n  I'm just glad we're seeing this garbage now instead of having an aneurysm in the prometric center +9
feanor  This Question is a perfect example of where you just jump off your seat to demand a refund or you decide to go Antisocial Disorder on your computer screen. +
olddoc  I don't think it has to do with any extra info. The dx is FAP (mutation in APC gene) which is inherited in an AUTOSOMAL DOMINANT fashion ("A" is the mutant allele and "a" is the normal one. The girl in the question stem MUST be heterozygote "Aa", getting the mutant "A" from her sick father and "a" from her healthy mother. Assuming she marries a healthy husband (aa) (this is a normal assumption in genetics questions), their kid will be Aa (the phenotype that will 100% result in CRC) by a probability of 50%. Recall that FAP will 100% progress to CRC is not prophylactically removed. +5
olddoc  FA 2019 Page 381 +
conniea168  It sucks because in psychiatry rotation as MS3 you may come across this fact that rate is ~50% in identical twins, but other than that it's unfair for Step 1 :/ +
epiglotitties  @olddoc wrong q +


submitted by kernicterusthefrog(139), visit this page
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"she feels happier and more relaxed" after starting kickboxing: this is a MATURE defense mechanism (classic textbook sublimation, as has been said). This question is just plain wrong. It's not displacement, because it's a healthy, socially acceptable outlet that improves her emotional state; punching bags are meant to be punched (thus it is actually NOT neutral). Displacement to an object would be punching a hole in her wall, or breaking her vase (I just like that imagery). Both of those would be better than punching her family, or breaking their car window, which is why it's displacement (unconscious redirection of an emotion to a safer object). However, kickboxing is LITERALLY an example in several psych textbooks for sublimation. Thank you for coming to my TED Talk.

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jaxx  Meanwhile, I thought everything was wrong so I went with another Mature defense mechanism. +17
happyhib_  What if, just what if. Her taking time to do lessions was actually hurting her children by her having less time to spend with them and in turn not providing good care for them. (less of a mature defense mech now). Trust me I agree completely just not best answer, but given what we are given you could argue beyond that; amboss even says "a mom showing her feelings of anger towards the child instead of the actual problem, the husband". So in a way she is not addressing her actual problem (which she COULD address). +1
kernicteruscandycorn  I support your assertion, fellow kernicterus +2
madamestep  I like to think of Sublimation as Regina George at the end of Mean Girls thriving at field hockey. +1


submitted by pppro(25), visit this page
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Patient has BPH. Give alpha one antagonist to reduce smooth muscle contraction and relieve difficulty urinating.

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d_holles  lol i thought it was some kind of urinary retention problem and put H. +17
sbryant6  How is H wrong? Oxybutinin or tolterodine treat urinary incontinence by blocking M3 muscarinic acetylcholine receptors --> urinary retention. We're just supposed to assume they are talking about BPH here because he is old? +1
jaxx  I agree. I picked "H" for that same logic. Does anyone know where we should have come to the conclusion that this was BPH? +
forerofore  they are telling you he's having "difficulty urinating", one of the clinical criteria for BPH is reduced urinary flow rate. this is not incontinence because they are not telling you he leaks at all, just that he pees "a lot" +13
drzed  Even if he was urinating too much, anticholinergics are contraindicated in the elderly (Beers criteria) +7
pathogen7  @drzed tI mean techinically alpha-1 blockers are on the Criteria too ... +2


submitted by seagull(1933), visit this page
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out of curiosity, how may people knew this? (dont be shy to say you did or didnt?)

My poverty education didn't ingrain this in me.

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johnthurtjr  I did not +3
nlkrueger  i did not lol +
ht3  you're definitely not alone lol +
yotsubato  no idea +
yotsubato  And its not in FA, so fuck it IMO +1
niboonsh  i didnt +
imnotarobotbut  Nope +
epr94  did not +
link981  I guessed it because the names sounded similar :D +18
d_holles  i did not +
yb_26  I also guessed because both words start with "glu"))) +30
impostersyndromel1000  same as person above me. also bc arginine carbamoyl phosphate and nag are all related through urea cycle. +1
jaxx  Not a clue. This was so random. +
ls3076  no way +
hyperfukus  no clue +
mkreamy  this made me feel a lot better. also, no fucking clue +1
amirmullick3  My immediate thought after reading this was "why would i know this and how does this make me a better doctor?" +10
mrglass  Generally speaking Glutamine is often used to aminate things. Think brain nitrogen metabolism. You know that F-6-P isn't an amine, and that Glucosamine is, so Glutamine isn't an unrealistic guess. +6
djtallahassee  yea, I mature 30k anki cards to see this bs +6
taediggity  I literally shouted wtf in quiet library at this question. +2
bend_nbme_over  Lol def didn't know it. Looks like I'm not going to be a competent doctor because I don't know the hexosamine pathway lol +25
drschmoctor  Is it biochemistry? Then I do not know it. +5
snoochi95  hell no brother +1
roro17  I didnโ€™t +
bodanese  I did not +
hatethisshit  nope +
jesusisking  I Ctrl+F'd glucosamine in FA and it's not even there lol +
batmane  i definitely guessed, for some reason got it down to arginine and glutamine +3
waterloo  Nope. +
monique  I did not +
issamd1221  didnt +
baja_blast  Narrowed it down to Arginine and Glutamine figuring the Nitrogen would have to come from one of these two but of course I picked the wrong one. Classic. +2
amy  +1 no idea! +
mumenrider4ever  Had no idea what glucosamine was +
feeeeeever  Ahhh yes the classic Glucosamine from fructose 6-phosphate question....Missed this question harder than the Misoprostol missed swing +1
surfacegomd  no clue +
schep  no idea. i could only safely eliminate carbamoyl phosphate because that's urea cycle +
chediakhigashi  nurp +
kidokick  just adding in to say, nope. +
flvent2120  Lol I didn't either. I think this is just critical thinking though. The amine has to come from somewhere. Glutamine/glutamate is known to transfer amines at the least +1
l0ud_minority  No fucking clue I guessed wrong:( +


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