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NBME 20 Answers

nbme20/Block 2/Question#6 (reveal difficulty score)
An 18-year-old boy has just been diagnosed ...
50% ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ

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submitted by โˆ—mcl(659),
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sihT gmeia is reyv uhlf.ple

submitted by โˆ—celeste(91),
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hileW teh metifeil iksr ni het elgerna tinpoaulpo si tujs woelb 1,% it is %65. ni e-siderfgrte tsalreevi of sniatpte dna it rsies to more ntah 40% in ngioooztmyc snwit fo edtaffce .pepeol Alnnyzgai iaccsls iesutds of eht eicsteng fo orespicnzhiah eodn as eylra as in s903,1 rhFiecs lucoecnds htat a caonrncoecd eatr rfo sspisyoch fo obaut 05% ni zoomotyncgi nwtsi eessm ot be a istiecarl ,semetati hhicw is cglsifyniinta ehgrih nath htat in gdyiziotc tniws of otbau 109%โ€“1 (is6n/go/i.i3tMcC5.3h/prrPac4/v6lmb2n9e#ne.fcml)

imnotarobotbut  Hwo is one osdeupps to wkno shit brfeeo ignvha erda hits ctralie? +36  
imgdoc  hiTs siunteoq salfl druen eht eehrti uoy nokw ti or uyo odnt tg.eracoy It stni ni FA ro Uwrdlo +2  
jaxx  oS hwy lwodu eeths Al-ohes put it no htree sa if pgnppeir for siht xmea in'ts lteusfsrs oguehn -:| +9  
doodimoodi  Llo tsuj hyw lrysoiuse +3  
champagnesupernova3  Tish was mntioneed ni hte nlKapa aolihervba edsvio +  
usmlecrasher  nda 'terehs os hucm ulsennrsecaiy BS itdenas of aler neqoistsu +3  
j44n  mI' sutj glad 'weer gsinee htis gaeabrg onw nesaitd fo gaivnh na euymrsan in eht rrimtcoep erecnt +8  
feanor  shTi Qnuseito is a ptrefce exapmel of wrhee you tujs upmj ffo yrou seat ot eanmdd a rnufed or oyu ddciee ot og aiiAtolncs ioDesdrr no uory ecproutm r.ecnse +  
olddoc  I tdon' hinkt ti ash to do thwi ayn txaer .foin hTe xd is FAP n(motuiat in CAP g)ene ciwhh is etdniireh ni an SAOAUTMOL IMTADNON aonsihf (""A si het attnmu llaele nad "a" is het aomnrl eo.n ehT ilgr in eht oqetnius etms TUSM eb etozyeehotgr A,""a etnggti teh mnattu "A" fmor her isck trafeh nda a"" ofmr hre aythhle htemor. mgAuinss hes aermris a lheayht uanhsbd )a(a s(tih si a mrlano ouistnsapm in nsteegci itesnuo),qs rihte dki iwll be aA et(h eoppeynht atht ilwl %001 eusrlt in RCC) by a bayipotrlbi fo .05% lcaRel htta PFA lwil 001% srrspgeo ot CCR is ton cyoacpiptllylahr eov.dmer +4  
olddoc  FA 2901 Page 831 +  
conniea168  tI usksc bsuecea ni ythasycrpi aontirot as S3M yuo may mceo cssroa tihs fcat ahtt reta is 0~5% ni acitnedil ,iwnst btu terho hatn thta its' anifru fro pSet 1 :/ +  

submitted by โˆ—peachespeaches(1),

Don't need to know this is FAP to get it right.

Father and Grandfather had it, so can assume an AD mutation in this patient. Assuming her partner is homozygous without the mutation, the risk of her AD train going to her child is 50%

peachespeaches  *AD trait +  
jonobauer  Wrong question +  
jonobauer  Wrong question +  

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