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Retired NBME 25 Answers

nbme25/Block 1/Question#18 (reveal difficulty score)
A 35-year-old man comes to the physician ...
Mitochondrial crystalline 🔍 / 📺 / 🌳 / 📖
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submitted by yogurt-dimple(3)
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Am I yaz,cr ro dseo eht sqnoiuet etms iplmy tath ihst was ehrtneidi lnaeaprt?yl

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raspberry-muffin  nI tshi qonutise udsosn leki iithnered nlptrlaaey , utb ihst ueclms sboiyp odminerfc iornlahtdMoci cietnhinar.e esMluc poisby: huiemtossrmoIhyncimt atlciyply hossw ggdrea dre sf,brei iwhch era cseadu by uslmlaae-bomscr dna -nlbioyraietrfrmil luactamuocin of cifdeevet irinmhtcadoo ni cesmslu n(doiirmhctoa tnais dr)e. Pybralob eotrhM sha the sema tioniondc ot.o +
yogurt-dimple  Gatoc.h h,eaY teh rde aggder sfierb peptid em ffo ot dtilnochraimo ,tmoyyaph tbu cbaseeu hte emst pmldiie aertlnpa ncaiirt,neeh I gferiud etreh aws sjut tonhaer iessead I hda nfrtooegt batou htat sterneps whit emh.t +
drdoom  fmrpabernsi-fr@yu 'Im ton vci.deonnc It is hhygil ylnikleu hte NEBM uwdlo tirwe this inotuqes nad epectx uyo ot mause"s" omm ash niiocdnto ihuotwt kamgin ayn ntmoeni fo o.mm ,ulPs it si pilmsy yighhl rpobbmaile tath mtaoyyhp is nsperte in boht mmo dna dad inel.gae Ttha emses off to em. +
drdoom  uym-ild@re,ogpt I ithnk shti a key lnie in the ploxaan:neit ev,“rHweo heter are noaiddtial tsutonaim atth aetfcf chinlaroimotd RNA atoinsnar,lt gtfriniackf adn torproinoainc fo iryerorspta topreni seoclexp,m dna timnananece of hte rinen tmlcroindihao mreneabm tath nac also aled to irdchlimotnoa ap”.tymhyo +
drdoom  eY,s yhet ,asy "inhoaMdrictlo sseaiesd aer crsltyti entehirid ohhugtr the mroteh" utb htsi si ton a ancolmrihtodi idseeas — ihst is a omhirvtiad"inc"nlden–or-ode rnctiiaomodlh thpayymo; ys,e cihortmoandi era adetefcf btu hte tuotmina si in omctsai la(cen)ur esgen hatt renogv the ntmeinaaenc of thyh"lea m.o"dnhoraicti sihT si sueaecb hte tmiuonat tcseaff the unoiintnotcrf/oepa of rncitidhooma ubt eth otntaimu itfesl si in eth aenurlc NAD hwihc( ortncol htgisenom aotub eth la"ut"yiq of dtoacmoirnhi but wath celyxat si not tye n)nko.w +


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submitted by drdoom(1206)
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ihTs oestuniq himtg be tcyrik sueecba eht antumiot fo eetntsri eerh si rediehtni morf teh add ised aprea(tln) ubt ceasftf the mroia.chodtni

Tath i,s het tamtinuo si tno a utiamnot fo het ndtclohimoria N;AD ti is of acleunr AND ihcwh casfetf hnomirtacldoi tuiofncn adn yqat.liu eim(ahsncM nwu)nkon.

In trieh xpointaaeln, het NEMB ,asys “oMiilndhtarco issedsea rea riylctts tdireehin ogthurh eht r”otehm tub htat is troe;rcnci it dlwuo eb oemr ocrtcer rfo hmte to ehva ad:is dioinclratMho DAN uttmosian aer crlsttyi ithneired thohrug het hr.omet

thaT ,si uyo cna eahv ahlconromiitd rbeomspl ttah emco mrof rouy d.da inrdMclhotaio NAD asn,uoitmt on teh oreth n,dha cmeo lyno rfom mm.o

,oS eth mtse eesdisrbc a “lhranodicomti eesisad” btu ti is ont a nmioiartldoch iseesad ieevdrd omrf a moctdnihriaol NAD oatimntu .

,eYs ntcohdarmoii are faedtcef tub teh tunamoti si in nulcrea DAN ttah ovrseng het ncaneimtena of leaty"hh .oiirctmhnado"

ishT leaxnisp wyh add dna 'dsda thbrreo shwo het seam ioxlrp“ma lescmu nwesskea fo the lwreo eeix”ittmers.

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drdoom  yCagilnifr trhr:fue heT sesidea fo netriest si brette erdbcsdei as a datcnnli"rnihom-oo eiANd–Dderv" odamrnohilitc myyh.oapt 'Its a fulmuhto, I o.nwk ,esY nmitihoarcod rae tdfceefa utb teh nattouim si in oicmsat rula)(nec egnes htat gnevro het amaiiupeontftninn/ronc/cneteoa of lhtah"ey oirtoimn"ach.d siTh is yhw it si igebn hterinied hgrhotu hte add dan eyt santmsfie in riatloocidhmn ydoncsf.inut +


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