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Retired NBME 25 Answers

nbme25/Block 1/Question#18 (reveal difficulty score)
A 35-year-old man comes to the physician ...
Mitochondrial crystalline 🔍 / 📺 / 🌳 / 📖
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submitted by yogurt-dimple(3)
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Am I rc,azy ro seod eth ioneuqts esmt ympil that this was eniehidrt apylraelt?n

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raspberry-muffin  nI itsh unositqe snsodu kile edrteinhi nlrytaplae , btu isht eulmcs spoiyb dfiemronc dMloohairtcin c.nenreitiah Mlceus bs:yipo uehtoImsmtyoihicmrsn lycayiptl osshw daggre rde s,eifbr hihcw are csuead by oaa-ssblummclre nda bnlyirelriaf-trmoi ccouuatamlin fo tiedeefvc thadnriiomoc ni eclumss oticnrmi(haod atsni )rde. Prloyabb Mohret has the emas oitnnicdo oo.t +
yogurt-dimple  .tcahGo Yeah, teh erd radgeg iesbrf tieppd me ffo ot atncihrodiolm ymohayp,t ubt esbeuac eht stme mldiipe rnpaeatl cnatn,ehirie I uirgefd erthe saw tusj nerhato adsisee I adh orftgtnoe atbuo ahtt rpenetss htiw .etmh +
drdoom  n@rsa-pmybfurrfie I'm otn incvnd.ceo tI is glyhhi llkuynei het NEBM ldwuo ewtir tihs qnitseou adn epcxte oyu to eau"ss"m omm has dotnoniic tuoitwh iamngk yan mnontie fo mmo. ,lsuP ti si yplsim hhlgiy rmbbeioapl hatt yhoaymtp is ernespt ni htob mom dan add lgaen.ie Ttha messe fof to .em +
drdoom  i-demor@tyl,upg I nkhit hsti a kye lien ni teh nxaltepao:in ,oweHrv“e eterh era ddnatlioia antutsomi ttha ffetac hilocomadritn NAR narstaontl,i kiifcartgnf dna iornioaorpctn fo poaytseirrr ropient ecexol,spm and nneamecnita fo the ennri incdthoimrola bnameemr ttha nca loas elad to dcntiohroalmi pytyh”oam. +
drdoom  sY,e yeth s,ay "hitioMrnadloc asdseies aer rscitytl dinhtreei orguhht eth rteoh"m but isht is not a imclniraoohdt idaeess — hist si a aoldihc–inetr-edvi""dornnom cnratmodiilho tpa;yhmyo yes, ohindtrmcoai aer faetdfec btu eth omatinut is in sictoam rnlue)ca( ngees tath goevnr teh ncmaaitneen fo tlh"heay ircnmt.ihoao"d shiT is buecase eht mtianout ffetcsa eth /inottncafeuoporni of oaimdroncthi but eht timauton tflesi is in teh eucanlr AND hwi(hc lrtncoo mgthsoein abtou the ""tyualqi fo oindtoachimr but ahwt cteyxal si nto yte .)knonw +


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submitted by drdoom(1206)
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hisT unetsqio hitgm eb ykrtci eusecab eth aotumint of etnitser ereh is rdetheini morf eht dad sedi lrtan(pea) btu cfatesf hte oci.othanrmid

hTta ,is eht omauitnt is ont a amtontui of eth toimailcnhodr N;AD it si fo unlaecr DNA ihcwh fcsetaf iatrdocoilnmh intucfon dan yalqu.ti msi(heacMn ).unnowkn

nI ethri ,npaaxitloen het ENMB s,asy “hnaMoilctidor sdeieass ear rtticsyl eidrnheit gutrhoh teh ”ehtmro tbu htat is enrcotcri; it uolwd eb emor rocrtce rfo meht ot vhae s:dai oMicidlontrah AND ttuamnsoi are yrtislct reihndtei rhotugh het m.oerht

thaT is, yuo nac ehva motciidnalorh eolpmbrs ahtt ceom ofrm ouyr da.d adMotolnciirh AND unaismot,t no het eorht h,adn omce yonl orfm .omm

S,o eht tsme dseecsrbi a “ramlotoiicdhn easeisd” btu ti si ton a arlotchidomni seiaeds reevddi form a cnatlmihrooid NAD n.tmat iuo

,esY ticoodmhianr are dfeatfce tbu het nmttouia is ni nalecur DNA atth osrnevg eht tnnemnceaia fo lahthy"e omhinra"ctodi.

Thsi lxasipne why dad and ddas' beotrrh oshw eht asem lramopix“ sucelm keaswnse of eth lwreo e”tesi.xtmrei

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drdoom  anfiCyiglr turfhre: Teh eseadis fo titsenre is rteebt debescird as a "chooomnn-ndiiratl edreADN–div" colaohintdimr oymth.pay tI's a mfhto,ulu I kwo.n eY,s natoidmhrioc are aefcdeft utb teh inauomtt si in ctisoma enual)rc( sgnee htat vogern eth rt/nuan/eiitnnoetcfmaenapocnoi of e"ahtlhy nac"ioroimtdh. Tish si yhw ti is ngebi dentiiher hhougtr hte dda dna tey ssatfmein ni hantolicmrdoi yuto.cfnidns +


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