Recall that red infarcts happen not only when there is venous occlusion and ischemia in organs with multiple blood supplies (such as the liver, lung, intestine, and testes) BUT ALSO WHEN there is reperfusion injury, mainly after angioplasty. Reperfusion injury is due to the production of free radicals and peroxides. Reperfusion injury can also happen after thrombolytic therapy. This is also seen in the first 0-24 hrs of myocardial infarction where reperfusion injury can cause free radicals and increased Calcium influx.
So why then is E) Protease inactivation by cytoplasmic free calcium ions incorrect? Although altered membrane permeability as a result of oxidative damage leads to changes in calcium flux and a rise in intracellular calcium, this intracellular calcium leads to ACTIVATION, rather than inactivation.
submitted by โshak360(19)
Recall that red infarcts happen not only when there is venous occlusion and ischemia in organs with multiple blood supplies (such as the liver, lung, intestine, and testes) BUT ALSO WHEN there is reperfusion injury, mainly after angioplasty. Reperfusion injury is due to the production of free radicals and peroxides. Reperfusion injury can also happen after thrombolytic therapy. This is also seen in the first 0-24 hrs of myocardial infarction where reperfusion injury can cause free radicals and increased Calcium influx.
So why then is
E) Protease inactivation by cytoplasmic free calcium ionsincorrect? Although altered membrane permeability as a result of oxidative damage leads to changes in calcium flux and a rise in intracellular calcium, this intracellular calcium leads to ACTIVATION, rather than inactivation.