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NBME 25 Answers

nbme25/Block 2/Question#43 (reveal difficulty score)
A previously healthy 43-year-old man comes to ...
Polyarteritis nodosa (PAN) ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ
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submitted by โˆ—shak360(14)

See pages from FA 2020 and other resources.

The moment we see HepB seropositivity, cutaneous eruptions, and different stages of TRANSMURAL INFLAMMATION WITH FIBRINOID NECROSIS, we should be thinking Polyarteritis nodosa (PAN). It is treated with corticosteroids and cyclophosphamide.

This patient had segmental transmural necrotizing arteritis making PAN the best answer.

Recall that for Giant cell arteritis or temporal arteritis, one would see a headache, temporal tenderness, jaw claudication, and fever.




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