Many objects on histology have a distinctive "fried egg" appearance, or cells that have a somewhat clear cytoplasm with central dark nuclei with distinct borders:

• Mycoplasma pneumonia colonies on Eaton agar
• Oligodendroglioma cells
• Seminoma and Dysgerminoma cells (large cells with clear cytoplasm, distinct borders)
• Parietal cells of the stomach due to their large size, central and round nucleus, and intensely acidophilic cytoplasm (in the middle region of the gastric gland)
• Plasma cells in Multiple Myeloma (more commonly associated with clock face or cartwheel chromatin pattern in the nucleus)
• Malassezia furfur (Tinea versicolor) (more commonly associated with a "spaghetti and meatballs" or :flying spaghetti monster" appearance on microscopy)