5a-Reductase catalyzes the metabolism of testosterone to DHT.
Individuals with 5a-reductase deficiency exhibit decreased concentrations of DHT and impaired virilization of the male urogenital tract.
Individuals with 5a-reductase deficiency appear phenotypically female externally or may have ambiguous external genitalia, with normal male internal genitalia.
submitted by โnamesthegame22(13)
5a-Reductase catalyzes the metabolism of testosterone to DHT.
Individuals with 5a-reductase deficiency exhibit decreased concentrations of DHT and impaired virilization of the male urogenital tract.
Individuals with 5a-reductase deficiency appear phenotypically female externally or may have ambiguous external genitalia, with normal male internal genitalia.