Urinary incontinence drugs
Muscarinic antagonists (oxybutynin) downregulate the M3 receptor leading to relaxation of detrusor smooth muscle and decreased detrusor overactivity.
In general, oxybutynin, solifenacin, and tolterodine reduce bladder spams and urge incontiencen.
Sympathomimetics (mirabegron) upregulate the ร3 receptor and relax the detrusor smooth muscle and increase bladder capacity.
submitted by โshak360(19)
Urinary incontinence drugs
Muscarinic antagonists (oxybutynin) downregulate the M3 receptor leading to relaxation of detrusor smooth muscle and decreased detrusor overactivity.
In general, oxybutynin, solifenacin, and tolterodine reduce bladder spams and urge incontiencen.
Sympathomimetics (mirabegron) upregulate the ร3 receptor and relax the detrusor smooth muscle and increase bladder capacity.