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Retired NBME 27 Answers

nbme27/Block 4/Question#8 (reveal difficulty score)
An 86-year-old man is brought to the ...
Inadequate hydroxylation of procollagen ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
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submitted by โˆ—shak360(19)
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Swollen gums, mucosal bleeding, poor wound healing, petechiae - Scurvy (vitamin C deficiency: can't hydroxylate proline/lysine for collagen synthesis)


Scurvy โ€” swollen gums, easy bruising, petechiae, hemarthrosis, anemia, poor wound healing, perifollicular and subperiosteal hemorrhages, โ€œcorkscrewโ€ hair. Weakened immune response.

Vitamin C deficiency causes sCurvy due to a Collagen synthesis defect.

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