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Retired NBME 30 Answers

nbme30/Block 1/Question#31 (reveal difficulty score)
Optimal diagnostic cut point for the results ...
B on the curve. ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
tags: biostats repeat

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submitted by โˆ—namesthegame22(13)
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The cut point of a test should be set to optimize sensitivity, specificity, or both depending on the clinical utility of the test.

A more sensitive test should be employed when ruling out a significantly mortal or morbid diagnosis.

There is overlap between the two, suggesting that some patients will test equivalently on the test but may or may not have the disease. Setting the cut point to point B would permit all patients within the area under the infected curve to be identified as positive, which maximizes sensitivity, while minimizing the number of false positives, and therefore optimizing specificity while prioritizing sensitivity.

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maximus  The way I think about sensitivity is that sensitivity is only concerned with sick people (true positives divided by the sum of true positives + false negatives). Sensitivity doesn't rule out anything: it is only a measure of how well you identity the disease (in those that HAVE the disease). https://upload.wikimedia.org/wikipedia/commons/thumb/5/5a/Sensitivity_and_specificity_1.01.svg/341px-Sensitivity_and_specificity_1.01.svg.png +



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