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NBME 30 Answers

nbme30/Block 1/Question#39 (reveal difficulty score)
Graph shows the mean steady-state plasma ...
Greater volume of distribution ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
tags: pharm

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submitted by โˆ—namesthegame22(11)

The volume of distribution is a theoretical volume in which a drug exists based on its plasma concentration.

It is altered by changes in volume of the intravascular, interstitial, and intracellular compartments.

Increases in volume of distribution are exhibited by a slower rate of increase in plasma drug concentration and a prolonged period before reaching steady-state concentration. (slower to reach the plateau)

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