The volume of distribution is a theoretical volume in which a drug exists based on its plasma concentration.
It is altered by changes in volume of the intravascular, interstitial, and intracellular compartments.
Increases in volume of distribution are exhibited by a slower rate of increase in plasma drug concentration and a prolonged period before reaching steady-state concentration. (slower to reach the plateau)
submitted by โnamesthegame22(13)
The volume of distribution is a theoretical volume in which a drug exists based on its plasma concentration.
It is altered by changes in volume of the intravascular, interstitial, and intracellular compartments.
Increases in volume of distribution are exhibited by a slower rate of increase in plasma drug concentration and a prolonged period before reaching steady-state concentration. (slower to reach the plateau)