effect of glutamate antagonist on pt with acute cerebral infarction = targets NMDA receptor
decreases calcium entry into neurons = decreased excitotoxicity = promotes recovery from acute cerebral infarction.
Tish noe asw tyrcik tbu I khint you uvdeoclโ dnoe hist eon iuhttow oldnkweeg fo AMDN erscper.ot Stem odtl uoy atht ttgmuaale tvasictae htbo n-AoNDMn dna ANMD rsopertec but ti vaettacid lony ND-AMnon etrcroeps in eht ylrae sap.he aTht aesnm NMDA soreprcte ticaavet reatf nDnMNAo- oes.ecprtr Ttah nemas nomgteshi aws galnediy MAND peroetrc caiganttiv nad eht nylo rweans ttha eadm sseen sa teh Mg ihgnbiiitn NDMA ta intsgre eianotl.pt enOc eth ecll si lidoezdrpea by AD-oNMnn ospctee,rr DMAN oecersprt anc eb c.tetvdaai
tA trisegn eabermnm ltotpeian hte NDAM rteocpesr are kceblod by .g+M2 ehT vatlego eenenddtp +2Mg okclb si eeevirld uonp ioortznpliaaed of the sysntpoa-cpti meabenmr . Teh gainld pdeedntne ciatvaonti of eht MDAN rcrpeteo esrrieuq oo-cavctaitni by tow ignsld,a mnyela gumtatlae nad elycgni.
An ttpomanir raeletd acclinil noipptlacia si rgm:einebrem vOnraia mteraoat nad eithr ansoisscoait wti:h -DtANMiAn prcreoet .nteiclaeihsp isTh pessrtne s:a icactishrPy ecbdarnt,sui yemorm tice,sfid iueerssz, kssiyesandi, omutcnoia liia,yttnsib gnleaagu .yfsuoctndin
A:F 0220; pg 282
o'ndt ftrego auobt hte gM kocb!l . . . . . .
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