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Retired NBME 13 Answers

nbme13/Block 2/Question#5 (reveal difficulty score)
A 4-year-old girl has had "puffy" eyes for ...
Loss of negative glomerular charge ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
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submitted by โˆ—tinacolada(4)
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This child has minimal change disease, the most common cause of nephrotic syndrome in children. It is often primary (idiopathic) and may be triggered by a recent infection, immunization, or other immune stimulus. Histologically, there is a loss of negative glomerular charge and selectively loses albumin which is why this child also presents with proteinuria. Source: FA19 p584.1

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