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Retired NBME 13 Answers

nbme13/Block 1/Question#13 (reveal difficulty score)
An 18-month-old boy is brought to the ...
Iduronate sulfatase ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
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submitted by cv020496(1)
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Hurler syndrome (Auto Rec) symptoms - Developmental delay, gargoylism, airway obstruction, corneal clouding, hepatosplenomegaly. Deficient - ฮฑ-l-iduronidase accumulation of- Heparan sulfate,dermatan sulfate

Hunter syndrome (X-linked Rec) - Mild Hurler + aggressive behavior, no corneal clouding. deficient - Iduronate sulfatase Build up - Heparan sulfate,dermatan sulfate

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