ACTH-secreting pituitary adenoma (Cushing disease); paraneoplastic ACTH secretion (eg,
small cell lung cancer, bronchial carcinoids)โresult in ACTH, bilateral adrenal hyperPLASIA.
Cushing disease is responsible for the majority of endogenous cases of Cushing syndrome. Cortisol produced in zona fasciculata in cortex.
submitted by cv020496(1)
ACTH-secreting pituitary adenoma (Cushing disease); paraneoplastic ACTH secretion (eg, small cell lung cancer, bronchial carcinoids)โresult in ACTH, bilateral adrenal hyperPLASIA. Cushing disease is responsible for the majority of endogenous cases of Cushing syndrome. Cortisol produced in zona fasciculata in cortex.