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NBME 25 Answers

nbme25/Block 1/Question#49 (reveal difficulty score)
A 50-year-old man with type 2 diabetes ...
Sitagliptin ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
tags: endo

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submitted by โˆ—namesthegame22(13)
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DM drug that promotes the release of endogenous insulin is initiated to improve glucose control=

DPP-4 inhibitors prevent the early breakdown of incretins, which promote endogenous insulin release.

(Sitagliptin is an example of this class of inhibitors.) They are generally used once metformin, diet, exercise, weight loss, or additional medications have failed to appropriately control a patient's blood glucose.

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shak360  See this question in NBME 27. +1
shak360  See this other question in block 2 on the action of glucagon or IV glucose in the treatment of hypoglycemia in DM type I. +



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